ACE, angiotensin I converting enzyme, 1636

N. diseases: 1082; N. variants: 82
Source: ALL
Disease Type Disease Class Semantic Type N. genes d N. SNPs d Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
CUI: C0242528
Disease: Azotemia
Azotemia 		disease Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases Disease or Syndrome 9 0.010 None < 0.001 1 2000 2000
CUI: C0262395
Disease: Borderline hypertension
Borderline hypertension 		disease Cardiovascular Diseases Disease or Syndrome 3 0.010 None < 0.001 1 1996 1996
CUI: C0262417
Disease: Acute on chronic pancreatitis
Acute on chronic pancreatitis 		disease Digestive System Diseases Disease or Syndrome 18 7 0.010 None < 0.001 1 2009 2009
CUI: C0271084
Disease: Exudative age-related macular degeneration
Exudative age-related macular degeneration 		disease Eye Diseases Disease or Syndrome 158 109 0.010 None < 0.001 1 2019 2019
CUI: C0344911
Disease: Left ventricular dilatation
Left ventricular dilatation 		disease Congenital Abnormality 17 3 0.010 None < 0.001 1 1 1996 1996
CUI: C0410702
Disease: Adolescent idiopathic scoliosis
Adolescent idiopathic scoliosis 		disease Musculoskeletal Diseases Anatomical Abnormality 656 1178 0.010 None < 0.001 1 2016 2016
CUI: C0549622
Disease: Sexual Dysfunction
Sexual Dysfunction 		group Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Mental Disorders; Behavior and Behavior Mechanisms Mental or Behavioral Dysfunction 36 12 0.010 None < 0.001 1 2019 2019
CUI: C0554309
Disease: Prerenal uremia syndrome
Prerenal uremia syndrome 		disease Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases Disease or Syndrome 9 0.010 None < 0.001 1 2000 2000
CUI: C0565599
Disease: Maternal hypertension
Maternal hypertension 		disease Female Urogenital Diseases and Pregnancy Complications; Cardiovascular Diseases Disease or Syndrome 52 22 0.010 None < 0.001 1 2006 2006
CUI: C1265713
Disease: Trephine hole
Trephine hole 		disease Acquired Abnormality 5 0.010 None < 0.001 1 2018 2018
CUI: C1304470
Disease: Generalized vitiligo
Generalized vitiligo 		disease Skin and Connective Tissue Diseases Disease or Syndrome 43 16 0.010 None < 0.001 1 2005 2005
CUI: C1306762
Disease: Aortoiliac occlusive disease
Aortoiliac occlusive disease 		disease Disease or Syndrome 17 2 0.010 None < 0.001 1 2009 2009
CUI: C1836438
Disease: Familial neurocardiogenic syncope
Familial neurocardiogenic syncope 		disease Pathological Conditions, Signs and Symptoms; Nervous System Diseases Disease or Syndrome 16 1 0.010 None < 0.001 1 2005 2005
CUI: C1839839
Disease: MAJOR AFFECTIVE DISORDER 2
MAJOR AFFECTIVE DISORDER 2 		disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Mental Disorders Mental or Behavioral Dysfunction 185 34 0.310 None < 0.001 1 1 2000 2000
CUI: C2733158
Disease: Cerebral Small Vessel Diseases
Cerebral Small Vessel Diseases 		group Nervous System Diseases; Cardiovascular Diseases Disease or Syndrome 62 6 0.010 None < 0.001 1 2015 2015
CUI: C2875367
Disease: Complex regional pain syndrome I, unspecified
Complex regional pain syndrome I, unspecified 		disease Nervous System Diseases Disease or Syndrome 1 0.010 None < 0.001 1 2004 2004
CUI: C4049993
Disease: Aristolochic Acid Nephropathy
Aristolochic Acid Nephropathy 		disease Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases Disease or Syndrome 49 0.010 None < 0.001 1 2011 2011
CUI: C4237343
Disease: Overweight or obesity
Overweight or obesity 		phenotype Disease or Syndrome 35 17 0.010 None < 0.001 1 2009 2009
CUI: C4511452
Disease: Sporadic Parkinson disease
Sporadic Parkinson disease 		disease Nervous System Diseases Disease or Syndrome 179 65 0.010 None < 0.001 1 2009 2009
CUI: C0020651
Disease: Hypotension, Orthostatic
Hypotension, Orthostatic 		phenotype Nervous System Diseases; Cardiovascular Diseases Disease or Syndrome 82 21 0.030 None 0.333 3 1 2002 2009
CUI: C0403396
Disease: Steroid-sensitive nephrotic syndrome
Steroid-sensitive nephrotic syndrome 		disease Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases Disease or Syndrome 36 11 0.030 None 0.333 3 2004 2012
CUI: C0409959
Disease: Osteoarthritis, Knee
Osteoarthritis, Knee 		disease Musculoskeletal Diseases Disease or Syndrome 368 150 0.030 None 0.333 3 2003 2019
CUI: C0751075
Disease: Cancer of Digestive System
Cancer of Digestive System 		disease Digestive System Diseases; Neoplasms Neoplastic Process 71 15 0.030 None 0.333 3 2013 2019
CUI: C1175175
Disease: Severe Acute Respiratory Syndrome
Severe Acute Respiratory Syndrome 		disease Infections; Respiratory Tract Diseases Disease or Syndrome 117 1 0.320 None 0.333 3 2004 2007
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder 		disease Mental Disorders Mental or Behavioral Dysfunction 1183 839 0.570 None 0.500 9 1 2000 2019