Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0149778
Disease: Soft Tissue Infection
Soft Tissue Infection
0.100 GeneticVariation group BEFREE We conducted a study to determine in vitro susceptibility to vancomycin, daptomycin, linezolid and tedizolid in MRSA clinical isolates from adult patients with skin and soft tissue infections. 28432878 2017
CUI: C0149778
Disease: Soft Tissue Infection
Soft Tissue Infection
0.100 GeneticVariation group BEFREE To overcome the increasing difficulties in the clinical management of SSTI due to MRSA, new prophylactic and therapeutic approaches are urgently needed and a preventive vaccine would be welcome. 31299217 2019
CUI: C0149778
Disease: Soft Tissue Infection
Soft Tissue Infection
0.100 Biomarker group BEFREE A survey was performed to detect risk factors for S. aureus infection and for the presence of PVL toxin.S. aureus was isolated from 219 out of 314 (70%) patients with SSTI, of which two (0.9%) patients were MRSA-positive. 21681630 2012
CUI: C0149778
Disease: Soft Tissue Infection
Soft Tissue Infection
0.100 GeneticVariation group BEFREE There were 378 SSTIs from different patients requiring culture, of which 240 (63.5%) were of MRSA and 43 (11.4%) were of MSSA; 84.8% of S. aureus isolates were MRSA. 18685002 2008
CUI: C0149778
Disease: Soft Tissue Infection
Soft Tissue Infection
0.100 Biomarker group BEFREE High rates of CA-MRSA skin and soft tissue infection have been reported from Aboriginal communities. 17021102 2006
CUI: C0149778
Disease: Soft Tissue Infection
Soft Tissue Infection
0.100 Biomarker group BEFREE Tigecycline demonstrated comparable efficacy for treatment of MRSA soft tissue infections regardless of infection type, SCCmec, or PVL status. 24725736 2014
CUI: C0149778
Disease: Soft Tissue Infection
Soft Tissue Infection
0.100 Biomarker group BEFREE We collected MRSA strains isolated from outpatients with skin and soft-tissue infection (SSTI) at 107 medical facilities from 24 prefectures in 2010 and 2012. 25789579 2015
CUI: C0149778
Disease: Soft Tissue Infection
Soft Tissue Infection
0.100 Biomarker group BEFREE Ceftaroline MICs were determined by reference BMD and by Etest for 1242 MSSA and MRSA isolates collected between February and May 2012 from adult patients with community-acquired pneumonia or complicated skin and soft tissue infections; tests were performed across six European laboratories. 27798220 2017
CUI: C0149778
Disease: Soft Tissue Infection
Soft Tissue Infection
0.100 Biomarker group BEFREE Twenty MRSA isolates were detected from CAI, 17 were from skin and soft-tissue infections and 3 from other infections. 23731504 2013
CUI: C0149778
Disease: Soft Tissue Infection
Soft Tissue Infection
0.100 Biomarker group BEFREE Our results suggested intrafamilial transmission of MRSA could be initial phenomenon of wide transmission in a community, therefore CA-MRSA SSTI in children and their family members should be monitored closely in order to notice the spread of highly pathogenic and transmittable strains. 26091885 2015
CUI: C0149778
Disease: Soft Tissue Infection
Soft Tissue Infection
0.100 Biomarker group BEFREE LA-MRSA CC398 caused 24.3 BSIs per 1000 SSTIs among people with no livestock contact, which is similar to the ratio observed for other types of MRSA. 28575216 2017
CUI: C0149778
Disease: Soft Tissue Infection
Soft Tissue Infection
0.100 Biomarker group BEFREE The aim of this study was to characterise 10 PVL-positive MRSA isolates collected during February 2010 to January 2011 from skin and soft-tissue infections in the North Italian Province of Bolzano. 22481056 2012
CUI: C0149778
Disease: Soft Tissue Infection
Soft Tissue Infection
0.100 Biomarker group BEFREE Forty-seven children with CA-MRSA SSTIs were enrolled in this study. 20055778 2010
CUI: C0149778
Disease: Soft Tissue Infection
Soft Tissue Infection
0.100 Biomarker group BEFREE The purpose of this review is to provide a critical analysis of our current knowledge of virulence factors contributing to skin and soft-tissue infections caused by CA-MRSA. 18317037 2008
CUI: C0149778
Disease: Soft Tissue Infection
Soft Tissue Infection
0.100 Biomarker group BEFREE In summary, HIV-infected persons have a high incidence of CA-MRSA skin/soft tissue infections and a high rate of recurrence. 19530952 2009
CUI: C0149778
Disease: Soft Tissue Infection
Soft Tissue Infection
0.100 Biomarker group BEFREE We sequenced the complete genomes of 36 CA-MRSA clinical isolates from the predominant North American community acquired clonal type USA300 (18 SSTI and 18 severe infection-associated isolates). 23009684 2012
CUI: C0149778
Disease: Soft Tissue Infection
Soft Tissue Infection
0.100 Biomarker group BEFREE Meanwhile, case reports, case series and few studies have demonstrated the capability of LA-MRSA to cause all types of infections attributed to S. aureus in general including fatal courses.Human infections observed comprise e.g. bacteremia, pneumonia, osteomyelitis, endocarditis and many manifestations of skin and soft tissue infections. 26644311 2017
CUI: C0149778
Disease: Soft Tissue Infection
Soft Tissue Infection
0.100 Biomarker group BEFREE The predominance of SCCmec type IV or V CA-MRSA in soft tissue infection has also been indicated in Northern Taiwan. 26167865 2015
CUI: C0149778
Disease: Soft Tissue Infection
Soft Tissue Infection
0.100 AlteredExpression group BEFREE To determine whether another antimicrobial agent might enhance the activity of moxifloxacin against CA-MRSA, this study analysed its activity alone and in chequerboard combination with doxycycline, rifampicin, clindamycin, trimethoprim, sulfamethoxazole/trimethoprim (SXT) and vancomycin against recent SSTI clinical isolates, and also characterized the isolates for Panton-Valentine leukocidin (PVL), agr groups, staphylococcal cassette chromosome mec (SSCmec) types and delta-haemolysin production. 18349364 2008
CUI: C0149778
Disease: Soft Tissue Infection
Soft Tissue Infection
0.100 Biomarker group BEFREE Nose and throat carriage of MRSA and PVL-SA was low among recruits, despite a high incidence of SSTIs being reported, particularly cellulitis. 31357012 2020
CUI: C0149778
Disease: Soft Tissue Infection
Soft Tissue Infection
0.100 Biomarker group BEFREE We report an outbreak of 7 cases of skin and soft tissue infections due to a strain of CA-MRSA. 15963273 2005
CUI: C0149778
Disease: Soft Tissue Infection
Soft Tissue Infection
0.100 Biomarker group BEFREE We characterized 45 non-duplicate CA-MRSA strains implicated mainly in skin and soft tissue infections (SSTIs) in a tertiary care hospital in Mysore, South India. 26044198 2015
CUI: C0149778
Disease: Soft Tissue Infection
Soft Tissue Infection
0.100 Biomarker group BEFREE The majority of patients hospitalized with community-associated S. aureus infections were due to MRSA, most of which involved an SSTI. 17070598 2007
CUI: C0149778
Disease: Soft Tissue Infection
Soft Tissue Infection
0.100 Biomarker group BEFREE These infections were chiefly SSTIs, although urinary tract infections were also noted.Incidences of CO-MRSA blood-stream infections and outpatient skin and soft tissue infections have been increasing with time, except in Tasmania. 30805180 2019
CUI: C0149778
Disease: Soft Tissue Infection
Soft Tissue Infection
0.100 Biomarker group BEFREE The S. aureus populations showed a high proportion of PVL-carrying strains, with frequencies ranging up to 70% in MRSA isolated from jail inmate patients and 69% in MRSA from patients receiving surgical treatment at an outpatient clinic specializing in treating SSTIs. 15131173 2004