Cardiomyopathy, Dilated
|
0.320 |
Biomarker
|
group |
HPO |
|
|
|
Cardiomyopathy, Dilated
|
0.320 |
Biomarker
|
group |
MGD |
|
|
|
Myopathy
|
0.110 |
Biomarker
|
group |
HPO |
|
|
|
Sensorineural Hearing Loss (disorder)
|
0.100 |
Biomarker
|
disease |
HPO |
|
|
|
Lipodystrophy
|
0.100 |
Biomarker
|
disease |
HPO |
|
|
|
Creatine phosphokinase serum increased
|
0.100 |
Biomarker
|
phenotype |
HPO |
|
|
|
Neutrophil abnormality
|
0.100 |
Biomarker
|
phenotype |
HPO |
|
|
|
Electromyogram abnormal
|
0.100 |
Biomarker
|
phenotype |
HPO |
|
|
|
Lipoatrophy
|
0.100 |
Biomarker
|
disease |
HPO |
|
|
|
Keratoderma, Palmoplantar
|
0.100 |
Biomarker
|
disease |
HPO |
|
|
|
Liver carcinoma
|
0.330 |
AlteredExpression
|
disease |
BEFREE |
Strongly positive expression of CAP2 was observed in 10 of 16 (63%) poorly, 30 of 68 (44%) moderately, and 2 of 21 (10%) well differentiated HCC.
|
23022774 |
2013 |
Neoplasm Metastasis
|
0.020 |
AlteredExpression
|
phenotype |
BEFREE |
CAP2 expression was significantly associated with tumor size, poor differentiation, portal vein invasion, and intrahepatic metastasis.
|
23022774 |
2013 |
Neoplasms
|
0.020 |
AlteredExpression
|
group |
BEFREE |
CAP2 expression was significantly associated with tumor size, poor differentiation, portal vein invasion, and intrahepatic metastasis.
|
23022774 |
2013 |
Liver carcinoma
|
0.330 |
Biomarker
|
disease |
BEFREE |
These genes not only include known HCC-relevant genes such as MT1X, BMI1, and CAP2, but also include cancer genes that were not found previously to be closely related to HCC, such as TACSTD2.
|
25247452 |
2015 |
Liver carcinoma
|
0.330 |
Biomarker
|
disease |
CTD_human |
Computational Discovery of Niclosamide Ethanolamine, a Repurposed Drug Candidate That Reduces Growth of Hepatocellular Carcinoma Cells In Vitro and in Mice by Inhibiting Cell Division Cycle 37 Signaling.
|
28284560 |
2017 |
Conduction disorder of the heart
|
0.010 |
Biomarker
|
group |
BEFREE |
Finally, of the 42 suggestively associated loci, AJAP1 was suggestively associated with QT in a prior East Asian GWAS; in contrast BVES and CAP2 murine knockouts caused cardiac conduction defects.
|
29213071 |
2017 |
Liver carcinoma
|
0.330 |
AlteredExpression
|
disease |
BEFREE |
Cyclase-associated protein 2 (CAP2) protein is reported to be upregulated in hepatocellular carcinoma (HCC), human breast cancer, and malignant melanoma.
|
30047046 |
2018 |
Neoplasm Metastasis
|
0.020 |
AlteredExpression
|
phenotype |
BEFREE |
For the first time, we found that CAP2 was upregulated in gastic cancer, and was associated with lymph node and distant metastases.
|
30047046 |
2018 |
Neoplasms
|
0.020 |
AlteredExpression
|
group |
BEFREE |
Statistical analysis shows that the expression of CAP2 was correlated with tumor size, Lauren's classification, depth of invasion, lymph node and distant metastases, and regional lymph node stage, TNM stage, but not with age, sex, histology classification, and histologic differentiation.
|
30047046 |
2018 |
Atrial Fibrillation
|
0.010 |
Biomarker
|
disease |
BEFREE |
We studied the device arms of 4 prospective Food and Drug Administration trials: PROTECT-AF (Watchman Left Atrial Appendage System for Embolic Protection in Patients With Atrial Fibrillation) (n=463); PREVAIL (Evaluation of the Watchman LAA Closure Device in Patients With Atrial Fibrillation Versus Long Term Warfarin Therapy) (n=269); CAP (Continued Access to PROTECT AF registry) (n=566); and CAP2 (Continued Access to PREVAIL registry) (n=578).
|
29752398 |
2018 |
Malignant neoplasm of breast
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Cyclase-associated protein 2 (CAP2) protein is reported to be upregulated in hepatocellular carcinoma (HCC), human breast cancer, and malignant melanoma.
|
30047046 |
2018 |
Malignant Neoplasms
|
0.010 |
Biomarker
|
group |
BEFREE |
CAP2 may serve as a prognostic indicator for patients with gastic cancer.
|
30047046 |
2018 |
Malignant neoplasm of stomach
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
However, its expression in gastric cancer remains unknown, this study was to investigate CAP2 expression and its prognostic significance in gastric cancer.
|
30047046 |
2018 |
melanoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Cyclase-associated protein 2 (CAP2) protein is reported to be upregulated in hepatocellular carcinoma (HCC), human breast cancer, and malignant melanoma.
|
30047046 |
2018 |
Breast Carcinoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Cyclase-associated protein 2 (CAP2) protein is reported to be upregulated in hepatocellular carcinoma (HCC), human breast cancer, and malignant melanoma.
|
30047046 |
2018 |