Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Ki-1+ Anaplastic Large Cell Lymphoma
0.010 AlteredExpression disease BEFREE <i>DUSP22-</i>rearranged ALCLs also overexpressed immunogenic cancer-testis antigen (CTA) genes and showed marked DNA hypomethylation by reduced representation bisulfate sequencing and DNA methylation arrays. 30093402 2018
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.010 Biomarker group BEFREE (1) Patients with HIE, who had a history of stroke and hypertension, showed more severe stenosis on CTA and more perfusion abnormalities compared to non-HIE patients (p < 0.05). 28454490 2017
CUI: C0752304
Disease: Hypoxic-Ischemic Encephalopathy
Hypoxic-Ischemic Encephalopathy
0.010 Biomarker disease BEFREE (1) Patients with HIE, who had a history of stroke and hypertension, showed more severe stenosis on CTA and more perfusion abnormalities compared to non-HIE patients (p < 0.05). 28454490 2017
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.050 Biomarker group BEFREE 4D-CTA with a wide scan range and precise injection timing methods facilitated an anatomical approach to tumor-related vascular structures, providing detailed vascular information. 28288528 2017
CUI: C0917996
Disease: Cerebral Aneurysm
Cerebral Aneurysm
0.010 Biomarker disease BEFREE 4D-CTA may be considered as a follow-up imaging tool for hemodynamic assessment of cerebral aneurysms. 31772042 2019
Arteriosclerotic cardiovascular disease, NOS
0.010 GeneticVariation disease BEFREE 6439 low-to-intermediate ASCVD-risk patients (57.9 ± 11.1 years; 44.4% females) who underwent CTA and CCS were enrolled. 31570324 2019
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.100 GeneticVariation disease BEFREE 73 asymptomatic individuals at increased risk of CAD due to peripheral vascular disease (18 women, mean age 63.5 ± 8.2 years) underwent coronary computed tomography angiography (coronary CTA) using first generation dual-source CT. Curvature and tortuosity of the coronary arteries were quantified using semi-automatically generated centerlines. 29486988 2018
CUI: C0085096
Disease: Peripheral Vascular Diseases
Peripheral Vascular Diseases
0.010 Biomarker group BEFREE 73 asymptomatic individuals at increased risk of CAD due to peripheral vascular disease (18 women, mean age 63.5 ± 8.2 years) underwent coronary computed tomography angiography (coronary CTA) using first generation dual-source CT. Curvature and tortuosity of the coronary arteries were quantified using semi-automatically generated centerlines. 29486988 2018
CUI: C1837454
Disease: SPINOCEREBELLAR ATAXIA 8
SPINOCEREBELLAR ATAXIA 8
0.020 Biomarker disease BEFREE Spinocerebellar ataxia type 8 (SCA8) is caused by the expansion of CTA/CTG triplet repeats on 13q21.Cases can be familial or sporadic. 15823478 2005
CUI: C0265101
Disease: Carotid artery occlusion
Carotid artery occlusion
0.040 Biomarker phenotype BEFREE Carotid artery occlusion was defined as 100% cross-sectional occlusion of the vessel lumen as documented on CTA or MRA and confirmed by digital subtraction angiography.RESULTSFour types (A-D) of radiographic COICA were identified. 29775153 2018
Congenital anomaly of coronary artery
0.010 GeneticVariation group BEFREE Coronary artery anomalies are relatively rare (approximately 1% on CTA). 30158328 2018
CUI: C0013362
Disease: Dysarthria
Dysarthria
0.010 Biomarker disease BEFREE Dysarthria and right-sided limb ataxia were newly developed before DWI (after p-CTA). 30593199 2018
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke
0.100 Biomarker disease BEFREE CTA in patients with acute ischemic stroke shows large individual variations of occlusion sites and degrees. 28302611 2017
CUI: C0018817
Disease: Atrial Septal Defects
Atrial Septal Defects
0.010 Biomarker group BEFREE A 3D model printed from the CTA was used to simulate device deployment, demonstrating successful exclusion of the sinus venosus ASD with return of the RUPV to the left atrium (LA). 29897667 2018
CUI: C1510586
Disease: Autism Spectrum Disorders
Autism Spectrum Disorders
0.010 Biomarker disease BEFREE A 3D model printed from the CTA was used to simulate device deployment, demonstrating successful exclusion of the sinus venosus ASD with return of the RUPV to the left atrium (LA). 29897667 2018
CUI: C1862389
Disease: ATRIAL SEPTAL DEFECT 1
ATRIAL SEPTAL DEFECT 1
0.010 Biomarker disease BEFREE A 3D model printed from the CTA was used to simulate device deployment, demonstrating successful exclusion of the sinus venosus ASD with return of the RUPV to the left atrium (LA). 29897667 2018
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.050 Biomarker group BEFREE A CTA # 2E-reactive human single-chain (sc)Fv was selected by panning the larger library on decreasing concentrations of biotinylated tumor-associated antigen in solution. 9853954 1998
CUI: C0003509
Disease: Aortitis
Aortitis
0.010 Biomarker disease BEFREE A CT without contrast showing infiltration around the aorta should, in some context, be promptly followed by Aortic CTA to search for acute aortitis among other less urgent differentials. 29903668 2018
CUI: C0742343
Disease: Acute Chest Syndrome
Acute Chest Syndrome
0.020 Biomarker disease BEFREE A retrospective observational case-control study was performed of 246 ED patients referred to coronary CTA with suspicion of ACS (56.5% male; mean age 53.3 ± 11.6 years) between October 2013 and August 2015.123 consecutive patients were scanned on 3rd generation DSCT, and a cohort of 123 patients matched by age, BMI and heart rate were identified who had undergone 2nd generation DSCT imaging utilizing the same standard clinical protocol. 28506470 2018
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.080 Biomarker group BEFREE A retrospective review of neck CTA studies in young patients with cryptogenic stroke over the past 6 years (<i>n</i> = 33) was performed to determine the prevalence of carotid webs compared with a control group of patients who received neck CTA studies for reasons other than ischemic stroke (<i>n</i> = 63). 28495950 2017
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke
0.100 Biomarker disease BEFREE A series of consecutive patients with a clinical diagnosis of brain death underwent CTA (case group), while the control group comprised patients with acute ischemic stroke in the same period. 31196858 2019
CUI: C1561643
Disease: Chronic Kidney Diseases
Chronic Kidney Diseases
0.010 Biomarker group BEFREE A theoretical insight to understand the molecular mechanism of dual target ligand CTA-018 in the chronic kidney disease pathogenesis. 30286109 2018
CUI: C0162871
Disease: Aortic Aneurysm, Abdominal
Aortic Aneurysm, Abdominal
0.020 Biomarker disease BEFREE A total of 168 patients undergoing successful EVAR for abdominal aortic aneurysms with CTA follow-up of at least 1 year were included. 31250171 2019
CUI: C0752156
Disease: Dural Arteriovenous Fistula
Dural Arteriovenous Fistula
0.020 Biomarker disease BEFREE A transverse-sigmoid dAVF was detected on magnetic resonance angiography (MRA) and three-dimensional-CT angiography (3D-CTA), with no cortical venous reflex. 30227805 2019
CUI: C0023434
Disease: Chronic Lymphocytic Leukemia
Chronic Lymphocytic Leukemia
0.010 Biomarker disease BEFREE Abbreviations: APC/C: Anaphase-Promoting Complex/Cyclosome; BAD: BCL2-Associated agonist of cell Death; BAK1: BCL2 Antagonist Kinase1; BAX: BCL2-Associated X; BCL2: B-cell Chronic Lymphocytic Leukaemia (CLL)/Lymphoma 2; BH: BCL2 Homology Domain; BID: BH3-Interacting domain Death agonist; BIM: BCL2-Interacting Mediator of cell death; BUB: Budding Uninhibited by Benzimidazoles; CDC: Cell Division Cycle; CDH1: Cadherin-1; CDK1: Cyclin-Dependent Kinase 1; CEP55: Centrosomal Protein (55 KDa): CIN: Chromosomal Instability; CTA: Cancer Testis Antigen; EGR1: Early Growth Response protein 1; ERK: Extracellular Signal-Regulated Kinase; ESCRT: Endosomal Sorting Complexes Required for Transport; GIN: Genomic Instability; MAD2: Mitotic Arrest Deficient 2; MCL1: Myeloid Cell Leukemia sequence 1; MPS1: Monopolar Spindle 1 Kinase; MYT1: MYelin Transcription factor 1; PLK1: Polo Like Kinase 1; PUMA: p53-Upregulated Mediator of Apoptosis; SAC: Spindle Assembly Checkpoint; TAA: Tumor-Associated Antigen. 30601084 2019