Influenza
|
0.020 |
Biomarker
|
disease |
BEFREE |
To study the putative function of O-acetyl-GD3, we established stably transfected AbC-1 amelanotic hamster melanoma cells with O-acetylesterase gene from influenza C virus to hydrolyze the O-acetyl group from O-acetyl-GD3.
|
10037466 |
1999 |
Influenza
|
0.020 |
Biomarker
|
disease |
BEFREE |
To elucidate the role of O-acetylated GD3 in tumorigenesis, we transfected F-11 cells with the O-acetylesterase gene from influenza C virus.
|
7547879 |
1995 |
Arteriosclerosis
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
A recently identified locus for coronary artery disease (CAD) tagged by rs8042271 is in a region of tight linkage disequilibrium (LD) between 2 genes (MFGE8, ABHD2) previously linked to atherosclerosis.
|
30861420 |
2019 |
Atherosclerosis
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
A recently identified locus for coronary artery disease (CAD) tagged by rs8042271 is in a region of tight linkage disequilibrium (LD) between 2 genes (MFGE8, ABHD2) previously linked to atherosclerosis.
|
30861420 |
2019 |
Hyperlipidemia
|
0.010 |
Biomarker
|
disease |
BEFREE |
When their expression levels were validated with RT-qPCR, the relative expression levels were lower (HDAC4) and higher (F2RL1, ABHD2, TM4SF1 and FAM13A) in hyperlipidemia than in normal controls (P < 0.05-0.01).
|
30045016 |
2018 |
leukemia
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Transplanted mice induced for expression of the O-acetylesterase in the ALL cells exhibited a reduction of leukemia to minimal cell numbers and significantly increased survival.
|
23478187 |
2013 |
Chronic Obstructive Airway Disease
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Results from the current study suggest that ABHD2 gene polymorphisms contribute to COPD susceptibility in the Chinese Han population.
|
25880496 |
2015 |
Neoplasms
|
0.010 |
AlteredExpression
|
group |
BEFREE |
Immunohistochemical analysis of ABHD2 expression in tumour specimens showed a positive correlation of ABHD2 immunoreactivity with high Gleason score and pathological N stage.
|
26854828 |
2016 |
Pulmonary Emphysema
|
0.010 |
Biomarker
|
disease |
BEFREE |
The human α/β hydrolase domain-containing protein 2 gene (ABHD2) plays a critical role in pulmonary emphysema, a major subset of the clinical entity known as chronic obstructive pulmonary disease (COPD).
|
25880496 |
2015 |
Malignant neoplasm of prostate
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
ABHD2 expression was examined in clinical samples of prostate cancer by immunohistochemistry.
|
26854828 |
2016 |
Prostate carcinoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
ABHD2 expression was examined in clinical samples of prostate cancer by immunohistochemistry.
|
26854828 |
2016 |
ovarian neoplasm
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
In clinical serous ovarian cancer specimens, low expression of ABHD2 was associated with platinum resistance and poor prognosis (p<0.05, respectively).
|
27323405 |
2016 |
Malignant neoplasm of ovary
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
In clinical serous ovarian cancer specimens, low expression of ABHD2 was associated with platinum resistance and poor prognosis (p<0.05, respectively).
|
27323405 |
2016 |
Childhood Leukemia
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Transplanted mice induced for expression of the O-acetylesterase in the ALL cells exhibited a reduction of leukemia to minimal cell numbers and significantly increased survival.
|
23478187 |
2013 |
Coronary Artery Disease
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
A recently identified locus for coronary artery disease (CAD) tagged by rs8042271 is in a region of tight linkage disequilibrium (LD) between 2 genes (MFGE8, ABHD2) previously linked to atherosclerosis.
|
30861420 |
2019 |
Carcinoma, Ovarian Epithelial
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
In clinical serous ovarian cancer specimens, low expression of ABHD2 was associated with platinum resistance and poor prognosis (p<0.05, respectively).
|
27323405 |
2016 |
Age related macular degeneration
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Joint Analysis of Nuclear and Mitochondrial Variants in Age-Related Macular Degeneration Identifies Novel Loci TRPM1 and ABHD2/RLBP1.
|
28813576 |
2017 |
Cerebrovascular accident
|
0.100 |
GeneticVariation
|
group |
GWASDB |
Genome-wide association analysis of ischemic stroke in young adults.
|
22384361 |
2011 |