Asthma
|
0.440 |
GeneticVariation
|
disease |
BEFREE |
The KIF3A rs12186803 risk allele interacted with food sensitization to increase asthma risk in children with eczema (P = 0.02).
|
30830718 |
2019 |
Asthma
|
0.440 |
GeneticVariation
|
disease |
GWASCAT |
Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.
|
31619474 |
2019 |
Asthma
|
0.440 |
GeneticVariation
|
disease |
GWASCAT |
Shared and distinct genetic risk factors for childhood-onset and adult-onset asthma: genome-wide and transcriptome-wide studies.
|
31036433 |
2019 |
Asthma
|
0.440 |
GeneticVariation
|
disease |
GWASCAT |
A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases.
|
29785011 |
2018 |
Asthma
|
0.440 |
Biomarker
|
disease |
BEFREE |
This work aimed to investigate the role of KIF3A in epithelium apoptosis and bronchial inflammation in asthma.
|
29156524 |
2018 |
Asthma
|
0.440 |
Biomarker
|
disease |
CTD_human |
The association between KIF3A rs7737031 and asthma was validated in 3 independent populations, further substantiating the validity of our gene selection approach.
|
21912604 |
2011 |
Asthma
|
0.440 |
GeneticVariation
|
disease |
BEFREE |
The association between KIF3A rs7737031 and asthma was validated in 3 independent populations, further substantiating the validity of our gene selection approach.
|
21912604 |
2011 |
Asthma
|
0.440 |
GeneticVariation
|
disease |
BEFREE |
Our findings suggest that the KIF3A gene and/or its polymorphisms might have a susceptibility effect on AIA, providing a new step toward controlling aspirin intolerance in asthmatics.
|
20922562 |
2011 |
Gastrointestinal Stromal Tumors
|
0.300 |
Biomarker
|
group |
CTD_human |
Hedgehog pathway dysregulation contributes to the pathogenesis of human gastrointestinal stromal tumors via GLI-mediated activation of KIT expression.
|
27793025 |
2016 |
Gastrointestinal Stromal Sarcoma
|
0.300 |
Biomarker
|
disease |
CTD_human |
Hedgehog pathway dysregulation contributes to the pathogenesis of human gastrointestinal stromal tumors via GLI-mediated activation of KIT expression.
|
27793025 |
2016 |
Bone Diseases, Developmental
|
0.300 |
Biomarker
|
group |
CTD_human |
Kinesin-2 controls development and patterning of the vertebrate skeleton by Hedgehog- and Gli3-dependent mechanisms.
|
17698054 |
2007 |
Polydactyly
|
0.300 |
Biomarker
|
disease |
CTD_human |
Here we demonstrate that conditional inactivation of the Kif3a subunit of the kinesin-2 intraflagellar transport motor in mesenchymal skeletal progenitor cells results in severe patterning defects in the craniofacial area, the formation of split sternum and the development of polydactyly.
|
17698054 |
2007 |
Craniofacial Abnormalities
|
0.300 |
Biomarker
|
group |
CTD_human |
Kinesin-2 controls development and patterning of the vertebrate skeleton by Hedgehog- and Gli3-dependent mechanisms.
|
17698054 |
2007 |
Dysostoses
|
0.200 |
Biomarker
|
disease |
MGD |
|
|
|
Polycystic Kidney, Autosomal Dominant
|
0.200 |
Biomarker
|
disease |
MGD |
|
|
|
POLYCYSTIC KIDNEY DISEASE 1
|
0.200 |
Biomarker
|
disease |
MGD |
|
|
|
Dermatitis, Atopic
|
0.130 |
Biomarker
|
disease |
BEFREE |
Our study indicates that KIF3A and OVOL1 are involved in the development of AD in the Chinese pediatric population.
|
26127003 |
2015 |
Dermatitis, Atopic
|
0.130 |
GeneticVariation
|
disease |
GWASCAT |
Meta-analysis identifies seven susceptibility loci involved in the atopic march.
|
26542096 |
2015 |
Dermatitis, Atopic
|
0.130 |
GeneticVariation
|
disease |
GWASCAT |
Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis.
|
26482879 |
2015 |
Dermatitis, Atopic
|
0.130 |
GeneticVariation
|
disease |
BEFREE |
To verify the association, between AE and rs479844, rs2164983, and rs2897442, target for OVOLI (11q13), ACTL9 (19p13.2), and in KIF3A (5q31) genes in the Italian population.
|
23278845 |
2013 |
Dermatitis, Atopic
|
0.130 |
GeneticVariation
|
disease |
BEFREE |
We also replicated the associations of the FLG, C11orf30, TMEM232-SLC25A46, TNFRSF6B-ZGPAT, OVOL1, ACTL9 and KIF3A-IL13 loci that were previously reported in GWAS of European and Chinese individuals and a meta-analysis of GWAS for atopic dermatitis.
|
23042114 |
2012 |
Dermatitis, Atopic
|
0.130 |
GeneticVariation
|
disease |
GWASCAT |
Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis.
|
22197932 |
2011 |
Dermatitis, Atopic
|
0.130 |
GeneticVariation
|
disease |
GWASDB |
Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis.
|
22197932 |
2011 |
Childhood asthma
|
0.110 |
GeneticVariation
|
disease |
GWASCAT |
Shared and distinct genetic risk factors for childhood-onset and adult-onset asthma: genome-wide and transcriptome-wide studies.
|
31036433 |
2019 |
Childhood asthma
|
0.110 |
GeneticVariation
|
disease |
GWASCAT |
Meta-analysis identifies seven susceptibility loci involved in the atopic march.
|
26542096 |
2015 |