CHEK2, checkpoint kinase 2, 11200

N. diseases: 297; N. variants: 261
Disease: Colorectal Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.700 GeneticVariation disease BEFREE To further our knowledge about the contribution of CHEK2 1100delC to cancer incidence we have analysed a series of 149 patients with multiple colorectal adenomas some of whom developed colorectal cancer. 14568168 2003
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.700 Biomarker disease CTD_human The CHEK2 1100delC mutation was, however, not the major predisposing factor for the HBCC phenotype but appeared to act in synergy with another, as-yet-unknown susceptibility gene(s). 12690581 2003
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.700 Biomarker disease GENOMICS_ENGLAND
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.700 GeneticVariation disease CLINVAR