|
Malignant tumor of colon
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
CNN3 showed positive expression in 6/8 breast and 9/11 colon cancer lines and in HeLa cells.
|
31798778 |
2019 |
|
Malignant neoplasm of stomach
|
0.010 |
Biomarker
|
disease |
BEFREE |
Calponin 3 Regulates Cell Invasion and Doxorubicin Resistance in Gastric Cancer.
|
30911294 |
2019 |
|
Neoplasms
|
0.010 |
Biomarker
|
group |
BEFREE |
PGK1 and CNN3 autoantibodies were identified as EFP/RLP-specific biomarkers, potentially suitable for further discriminating tumors with different malignant potential (PGK1: 7/22 (32%) patients with non-invasive EFP/RLP tumors vs 0/38 (p = 0.00044) and 0/20 (p = 0.0092) patients with other tumors and healthy controls, respectively; СNN3: 9/29 (31%) patients with malignant and borderline EFP/RLP tumors vs 0/31 (p = 0.00068) and 0/20 (p = 0.0067) patients with other tumors and healthy controls, respectively).
|
31326556 |
2019 |
|
Carcinogenesis
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
To dissect the role of CNN3 in carcinogenesis with a focus on colon cancer.
|
31798778 |
2019 |
|
Secondary malignant neoplasm of lymph node
|
0.010 |
Biomarker
|
disease |
BEFREE |
These results show the involvement of CNN3 in lymph node metastasis and resistance to chemotherapy in colon cancer and suggest that significant oncogenic pathways are involved in these CNN3-related actions.
|
31798778 |
2019 |
|
Colon Carcinoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
CNN3 showed positive expression in 6/8 breast and 9/11 colon cancer lines and in HeLa cells.
|
31798778 |
2019 |
|
Stomach Carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Calponin 3 Regulates Cell Invasion and Doxorubicin Resistance in Gastric Cancer.
|
30911294 |
2019 |
|
Congenital Abnormality
|
0.010 |
Biomarker
|
group |
BEFREE |
Embryos lacking Cnn3 exhibited massive malformation of the developing brain including exoencephaly, closure defects at the rostral neural tube, and strong enlargement of brain tissue.
|
29151265 |
2018 |
|
Colorectal Carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
We suggest that CNN3 takes part in cell projection and movement, and the detection and distribution of CNN3 may render prognostic information for predicting peritoneal seeding metastasis from primary colorectal cancer.
|
30114595 |
2018 |
|
Lupus Erythematosus, Systemic
|
0.010 |
Biomarker
|
disease |
BEFREE |
Anti-calponin 3 antibodies were evaluated in sera from patients with primary SS (n = 209), patients with systemic lupus erythematosus (SLE; n = 138), patients with myositis (n = 138), patients with multiple sclerosis (MS; n = 44), and healthy controls (n = 46) by enzyme-linked immunosorbent assay.
|
29749720 |
2018 |
|
Multiple Sclerosis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Anti-calponin 3 antibodies were evaluated in sera from patients with primary SS (n = 209), patients with systemic lupus erythematosus (SLE; n = 138), patients with myositis (n = 138), patients with multiple sclerosis (MS; n = 44), and healthy controls (n = 46) by enzyme-linked immunosorbent assay.
|
29749720 |
2018 |
|
Myositis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Anti-calponin 3 antibodies were evaluated in sera from patients with primary SS (n = 209), patients with systemic lupus erythematosus (SLE; n = 138), patients with myositis (n = 138), patients with multiple sclerosis (MS; n = 44), and healthy controls (n = 46) by enzyme-linked immunosorbent assay.
|
29749720 |
2018 |
|
Neoplasm Metastasis
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
We suggest that CNN3 takes part in cell projection and movement, and the detection and distribution of CNN3 may render prognostic information for predicting peritoneal seeding metastasis from primary colorectal cancer.
|
30114595 |
2018 |
|
Deformity
|
0.010 |
Biomarker
|
group |
BEFREE |
Embryos lacking Cnn3 exhibited massive malformation of the developing brain including exoencephaly, closure defects at the rostral neural tube, and strong enlargement of brain tissue.
|
29151265 |
2018 |
|
Neuropathy
|
0.010 |
Biomarker
|
group |
BEFREE |
Calponin 3 is a novel autoantigen.Antibodies against this protein are found in SS and associate with the subset of patients experiencing neuropathies.
|
29749720 |
2018 |
|
Sjogren's Syndrome
|
0.010 |
Biomarker
|
disease |
BEFREE |
Anti-calponin 3 antibodies were evaluated in sera from patients with primary SS (n = 209), patients with systemic lupus erythematosus (SLE; n = 138), patients with myositis (n = 138), patients with multiple sclerosis (MS; n = 44), and healthy controls (n = 46) by enzyme-linked immunosorbent assay.
|
29749720 |
2018 |
|
Malignant neoplasm of colon and/or rectum
|
0.010 |
Biomarker
|
disease |
BEFREE |
We suggest that CNN3 takes part in cell projection and movement, and the detection and distribution of CNN3 may render prognostic information for predicting peritoneal seeding metastasis from primary colorectal cancer.
|
30114595 |
2018 |
|
Epilepsy
|
0.010 |
Biomarker
|
disease |
BEFREE |
The elevated calponin-3 suggests that deregulation of actin filament dynamics in axonal and dendritic outgrowth and synaptic rearrangement may contribute to pathophysiology of epilepsy.
|
22119193 |
2012 |
|
Drug Resistant Epilepsy
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Our previous microarray scan has found an up-regulation of calponin-3 gene CNN3 in the temporal lobe of patients with drug-resistant epilepsy.
|
22119193 |
2012 |
|
Mucosa-Associated Lymphoid Tissue Lymphoma
|
0.010 |
GeneticVariation
|
disease |
LHGDN |
Mucosa-associated lymphoid tissue lymphoma: novel translocations including rearrangements of ODZ2, JMJD2C, and CNN3.
|
18927281 |
2008 |
|
Tumor Cell Invasion
|
0.030 |
Biomarker
|
phenotype |
BEFREE |
CNN3-silenced SW620 cells showed a reduction in collagen invasion and loss of mesenchymal markers.
|
31798778 |
2019 |
|
Tumor Cell Invasion
|
0.030 |
Biomarker
|
phenotype |
BEFREE |
We demonstrate that CNN3 contributes to cell invasion and resistance to doxorubicin in gastric cancer.
|
30911294 |
2019 |
|
Tumor Cell Invasion
|
0.030 |
AlteredExpression
|
phenotype |
BEFREE |
We further speculated that CNN3 expression might be altered in human placentas derived from pregnancies complicated by IUGR and preeclampsia, since these placental disorders have been described to go along with impaired trophoblast invasion.
|
25050546 |
2014 |
|
Phospholipid measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASDB |
Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.
|
23362303 |
2013 |
|
Fatty acid measurement
|
0.100 |
GeneticVariation
|
group |
GWASCAT |
Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.
|
23362303 |
2013 |