UHMK1, U2AF homology motif kinase 1, 127933

N. diseases: 31; N. variants: 2
Disease: Childhood Diffuse Large Cell Lymphoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0278840
Disease: Childhood Diffuse Large Cell Lymphoma
Childhood Diffuse Large Cell Lymphoma 		0.030 GeneticVariation disease BEFREE When compared with six other DLCL cell lines lacking t(9;14)(p13;q32), the KIS-1 cell line showed an 11-fold overexpression of PAX-5 mRNA and a significantly reduced expression of the p53 gene, which is normally regulated by PAX-5. 8943844 1996
CUI: C0278840
Disease: Childhood Diffuse Large Cell Lymphoma
Childhood Diffuse Large Cell Lymphoma 		0.030 Biomarker disease BEFREE KIS-1 cell line was established from a patient with diffuse large cell lymphoma of B-cell type carrying t(9;14). 9722295 1998
CUI: C0278840
Disease: Childhood Diffuse Large Cell Lymphoma
Childhood Diffuse Large Cell Lymphoma 		0.030 Biomarker disease BEFREE KIS-1 is the only known B-cell line derived from Ki-1-positive diffuse large cell lymphoma, and should be useful for defining the biological implications of Ki-1 antigen. 2852183 1988