|
Diffuse Large B-Cell Lymphoma
|
0.030 |
Biomarker
|
disease |
BEFREE |
KIS-1 is the only known B-cell line derived from Ki-1-positive diffuse large cell lymphoma, and should be useful for defining the biological implications of Ki-1 antigen.
|
2852183 |
1988 |
|
Adult Diffuse Large Cell Lymphoma
|
0.030 |
Biomarker
|
disease |
BEFREE |
KIS-1 is the only known B-cell line derived from Ki-1-positive diffuse large cell lymphoma, and should be useful for defining the biological implications of Ki-1 antigen.
|
2852183 |
1988 |
|
Childhood Diffuse Large Cell Lymphoma
|
0.030 |
Biomarker
|
disease |
BEFREE |
KIS-1 is the only known B-cell line derived from Ki-1-positive diffuse large cell lymphoma, and should be useful for defining the biological implications of Ki-1 antigen.
|
2852183 |
1988 |
|
Diffuse Large B-Cell Lymphoma
|
0.030 |
GeneticVariation
|
disease |
BEFREE |
When compared with six other DLCL cell lines lacking t(9;14)(p13;q32), the KIS-1 cell line showed an 11-fold overexpression of PAX-5 mRNA and a significantly reduced expression of the p53 gene, which is normally regulated by PAX-5.
|
8943844 |
1996 |
|
Adult Diffuse Large Cell Lymphoma
|
0.030 |
GeneticVariation
|
disease |
BEFREE |
When compared with six other DLCL cell lines lacking t(9;14)(p13;q32), the KIS-1 cell line showed an 11-fold overexpression of PAX-5 mRNA and a significantly reduced expression of the p53 gene, which is normally regulated by PAX-5.
|
8943844 |
1996 |
|
Childhood Diffuse Large Cell Lymphoma
|
0.030 |
GeneticVariation
|
disease |
BEFREE |
When compared with six other DLCL cell lines lacking t(9;14)(p13;q32), the KIS-1 cell line showed an 11-fold overexpression of PAX-5 mRNA and a significantly reduced expression of the p53 gene, which is normally regulated by PAX-5.
|
8943844 |
1996 |
|
Diffuse Large B-Cell Lymphoma
|
0.030 |
Biomarker
|
disease |
BEFREE |
KIS-1 cell line was established from a patient with diffuse large cell lymphoma of B-cell type carrying t(9;14).
|
9722295 |
1998 |
|
Adult Diffuse Large Cell Lymphoma
|
0.030 |
Biomarker
|
disease |
BEFREE |
KIS-1 cell line was established from a patient with diffuse large cell lymphoma of B-cell type carrying t(9;14).
|
9722295 |
1998 |
|
Childhood Diffuse Large Cell Lymphoma
|
0.030 |
Biomarker
|
disease |
BEFREE |
KIS-1 cell line was established from a patient with diffuse large cell lymphoma of B-cell type carrying t(9;14).
|
9722295 |
1998 |
|
Congenital chromosomal disease
|
0.010 |
Biomarker
|
group |
BEFREE |
We analysed PAX5/BSAP expression by Northern and Western blotting in a panel of haematological tumour cell lines with other chromosome abnormalities in comparison with that of KIS-1.
|
9722295 |
1998 |
|
Neoplasms
|
0.030 |
AlteredExpression
|
group |
BEFREE |
For comparison we have analyzed PAX-5 expression in another B-cell lymphoma, KIS-1, indicating that transcription from the distal PAX-5 promoter was increased in this tumor in agreement with the previously characterized translocation of the immunoglobulin Emicro; enhancer adjacent to PAX-5 exon 1A.
|
9808580 |
1998 |
|
Neoplasms
|
0.030 |
Biomarker
|
group |
BEFREE |
On the other hand, the KIS gene was overexpressed in NF1-associated plexiform neurofibromas and malignant peripheral nerve sheath tumors (MPNSTs) as compared to dermal neurofibroma which suggests a possible implication of KIS in the genesis of NF1-associated tumors.
|
12782393 |
2003 |
|
Nerve Sheath Tumors
|
0.010 |
AlteredExpression
|
group |
LHGDN |
Quantitative RT-PCR reveals a ubiquitous but preferentially neural expression of the KIS gene in rat and human.
|
12782393 |
2003 |
|
Plexiform Neurofibroma
|
0.010 |
AlteredExpression
|
disease |
LHGDN |
On the other hand, the KIS gene was overexpressed in NF1-associated plexiform neurofibromas and malignant peripheral nerve sheath tumors (MPNSTs) as compared to dermal neurofibroma which suggests a possible implication of KIS in the genesis of NF1-associated tumors.
|
12782393 |
2003 |
|
Malignant Peripheral Nerve Sheath Tumor
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
On the other hand, the KIS gene was overexpressed in NF1-associated plexiform neurofibromas and malignant peripheral nerve sheath tumors (MPNSTs) as compared to dermal neurofibroma which suggests a possible implication of KIS in the genesis of NF1-associated tumors.
|
12782393 |
2003 |
|
Schizophrenia
|
0.350 |
Biomarker
|
disease |
BEFREE |
These results provide preliminary evidence that the UHMK1 gene increases susceptibility to schizophrenia.
|
16978587 |
2007 |
|
Schizophrenia
|
0.350 |
Biomarker
|
disease |
LHGDN |
These results provide preliminary evidence that the UHMK1 gene increases susceptibility to schizophrenia.
|
16978587 |
2007 |
|
Schizophrenia
|
0.350 |
Biomarker
|
disease |
PSYGENET |
These results provide preliminary evidence that the UHMK1 gene increases susceptibility to schizophrenia.
|
16978587 |
2007 |
|
leukemia
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
We showed that KIS mRNA expression was increased in primary leukemia specimens (acute myelogenous leukemia (AML); 37, myelodysplastic syndrome (MDS); 72, acute lymphoblastic leukemia (ALL); 23), and the mean ratios of KIS to G3PDH in AML, MDS and ALL specimens were 3.62+/-0.68, 3.27+/-0.73 and 3.17+/-0.58, respectively.
|
18384876 |
2008 |
|
Acute lymphocytic leukemia
|
0.010 |
Biomarker
|
disease |
BEFREE |
We showed that KIS mRNA expression was increased in primary leukemia specimens (acute myelogenous leukemia (AML); 37, myelodysplastic syndrome (MDS); 72, acute lymphoblastic leukemia (ALL); 23), and the mean ratios of KIS to G3PDH in AML, MDS and ALL specimens were 3.62+/-0.68, 3.27+/-0.73 and 3.17+/-0.58, respectively.
|
18384876 |
2008 |
|
Childhood Acute Lymphoblastic Leukemia
|
0.010 |
Biomarker
|
disease |
BEFREE |
We showed that KIS mRNA expression was increased in primary leukemia specimens (acute myelogenous leukemia (AML); 37, myelodysplastic syndrome (MDS); 72, acute lymphoblastic leukemia (ALL); 23), and the mean ratios of KIS to G3PDH in AML, MDS and ALL specimens were 3.62+/-0.68, 3.27+/-0.73 and 3.17+/-0.58, respectively.
|
18384876 |
2008 |
|
Leukemia, Myelocytic, Acute
|
0.010 |
Biomarker
|
disease |
BEFREE |
We showed that KIS mRNA expression was increased in primary leukemia specimens (acute myelogenous leukemia (AML); 37, myelodysplastic syndrome (MDS); 72, acute lymphoblastic leukemia (ALL); 23), and the mean ratios of KIS to G3PDH in AML, MDS and ALL specimens were 3.62+/-0.68, 3.27+/-0.73 and 3.17+/-0.58, respectively.
|
18384876 |
2008 |
|
Leukemia, Myelocytic, Acute
|
0.010 |
AlteredExpression
|
disease |
LHGDN |
Moreover, we found that KIS protein was overexpressed in all 132 adults cases of various leukemias, including 37 AML (8 M1, 12 M2, 2 M3, 7 M4, 8 M5), 72 MDS (42 RAEB-I, 30 REAB-II) and 23 ALL (23 L2).
|
18384876 |
2008 |
|
Adult Acute Lymphocytic Leukemia
|
0.010 |
Biomarker
|
disease |
BEFREE |
We showed that KIS mRNA expression was increased in primary leukemia specimens (acute myelogenous leukemia (AML); 37, myelodysplastic syndrome (MDS); 72, acute lymphoblastic leukemia (ALL); 23), and the mean ratios of KIS to G3PDH in AML, MDS and ALL specimens were 3.62+/-0.68, 3.27+/-0.73 and 3.17+/-0.58, respectively.
|
18384876 |
2008 |
|
acute myeloid leukemia with multilineage dysplasia following myelodysplastic syndrome
|
0.010 |
Biomarker
|
disease |
BEFREE |
We showed that KIS mRNA expression was increased in primary leukemia specimens (acute myelogenous leukemia (AML); 37, myelodysplastic syndrome (MDS); 72, acute lymphoblastic leukemia (ALL); 23), and the mean ratios of KIS to G3PDH in AML, MDS and ALL specimens were 3.62+/-0.68, 3.27+/-0.73 and 3.17+/-0.58, respectively.
|
18384876 |
2008 |