CRP, C-reactive protein, 1401

N. diseases: 1483; N. variants: 15
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis
0.100 GeneticVariation disease BEFREE The present study aimed to examine the association between CRP gene polymorphism and clinical and laboratory findings in ankylosing spondylitis (AS) patients. 26480896 2016
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis
0.100 GeneticVariation disease BEFREE The observations that CTLA-4 +49A>G genotypes are associated with circulatory CRP levels and significantly less AS subjects carrying CTLA-4 higher-secretor -318 T allele suggest the level and regulation of inflammation in AS subjects may be pre-determined by and associated with CTLA-4 genotypes. 20030788 2010
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis
0.100 GeneticVariation disease BEFREE Functional <i>LILRA3</i> conferred an increased disease activity in AS patients (<i>P</i> < 0.0001 both for CRP and ESR, and <i>P</i> = 0.003 for BASDAI). 31620171 2019
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis
0.100 GeneticVariation disease BEFREE The correlation between STIM1 genetic polymorphisms and AS activity index (BASDAI, BASFI, BAS-G) as well as laboratory parameters of inflammation (erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP)) were tested. 23272049 2012
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis
0.100 GeneticVariation disease BEFREE The relationship between CRP gene polymorphism (rs2794521, rs3091244), ASDAS-CRP and ASDAS-ESR in ankylosing spondylitis. 31267817 2019
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis
0.100 GeneticVariation disease BEFREE There were significant differences of the level of WBC (white blood cell), Platelets, CRP (C-reactive protein) and ESR (erythrocyte sedimentation rate) between AS patients and controls (P<sub>all</sub><0.05). 29278768 2018
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis
0.100 GeneticVariation disease BEFREE Moreover, M694V is significantly associated with a higher level of erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) in AS patients. 25036284 2014
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis
0.100 Biomarker disease BEFREE C1M, C3M, and C4M2 were associated with ASDAS-CRP in AS and nr-axSpA after adjustment for age, gender, and disease duration. 31375691 2019
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis
0.100 Biomarker disease BEFREE Exercise habits and C-reactive protein may predict development of spinal immobility in patients with ankylosing spondylitis. 30022369 2018
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis
0.100 Biomarker disease BEFREE PBMCs (p=0.047) and T cells (p=0.035) SOCS1 decreased significantly in the AS subgroup with lower CRP than controls. 26812031 2016
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis
0.100 Biomarker disease BEFREE Baseline characteristics were similar regarding C-reactive protein, but differed for other variables, including the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) (range 3.5-6.3) and Ankylosing Spondylitis Disease Activity Score (ASDAS) (2.7-3.8) (both p < 0.0001). 30070923 2018
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis
0.100 Biomarker disease BEFREE To assess the validity of Assessment in Spondyloarthritis International Society (ASAS) endorsed Ankylosing Spondylitis Disease Activity Score (ASDAS) C-reactive protein (-CRP) and ASDAS erythrocyte sedimentation rate (-ESR) in axial spondyloarthritis (axSpA) and to estimate the cut-off values for male and female patients with axSpA. 27309497 2017
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis
0.100 Biomarker disease BEFREE Similarly, the strong associations between the cytokines or between IL-12 and ESR or CRP were observed in HLA-B27-positive AS patients. 17459079 2007
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis
0.100 Biomarker disease BEFREE The factors of stages (P = 0.002), HLA-B27 (P = 0.002), ESR (P = 0.001) and C-reactive protein (P = 0.000) were considered to be related to the expression of SP selectin, which indicated that SP-selectin might be involved in the development of AS. 26261626 2015
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis
0.100 Biomarker disease BEFREE Bath Ankylosing Spondylitis Disease Activity Index, Bath Ankylosing Spondylitis Metrology Index, Bath Ankylosing Spondylitis Functional Index scores, erythrocyte sedimentation rate, C-reactive protein, glycemia, total cholesterol, and triglyceride levels were also recorded.Patients with AS showed significantly lower values of mean and maximum IMT at the level of the common carotid (P = .02 and .04, respectively) and the carotid bulb (P = .0006 and .0005, respectively) compared to those of healthy controls. 29979389 2018
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis
0.100 Biomarker disease BEFREE There were no significant differences in BMD between AS patients with elevated CRP and the patients with normal CRP and PLT. 31851643 2019
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis
0.100 Biomarker disease BEFREE We describe three mother-daughter couples concordant for AS and HLA-B27, both treated with TNF-α inhibitors, for whom the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), Bath Ankylosing Spondylitis Functional Index (BASFI), and Ankylosing Spondylitis Disease Activity Score (ASDAS)-CRP were evaluated during a follow-up of 24 months. 25962691 2015
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis
0.100 Biomarker disease BEFREE The Bath AS Function Index and Bath AS Disease Activity Index were assessed in AS patients and levels of erythrocyte sedimentation rate and C-reactive protein were measured in AS and healthy groups. 29067128 2017
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis
0.100 Biomarker disease BEFREE To analyze the alteration of lipid profile and inflammatory markers in the serum of patients with gouty arthritis (GA), the levels of serum lipid profile, C-reactive protein (CRP), and erythrocyte sedimentation rates (ESRs) were measured in the serum of 69 gout patients, 35 patients with rheumatoid arthritis (RA), 23 patients with ankylosing spondylitis (AS)/spondyloarthropathy (SpA), and 25 patients with osteoarthritis (OA). 28445313 2017
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis
0.100 Biomarker disease BEFREE Compared with the carriers of G/G genotype, remarkably elevated erythrocyte sedimentation rate and serum C-reactive protein were observed in AS patients with G/A variant (87.06±49.40 vs. 55.53±42.99mm/h, P=.0126; 54.95±27.77 vs. 34.36±36.13mg/dl, P=.0116, respectively), and they always presented with inflammatory spinal pain (70.00% vs. 43.33%, P=0.0214) and suffered relatively mild sacroiliitis (65.00% vs. 41.67%, P=0.0431). 28610765 2017
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis
0.100 Biomarker disease BEFREE Serum retinol levels did not correlate with indices of disease activity defined serologically (C-reactive protein, erythrocyte sedimentation rate) or clinically (Bath AS Disease Activity Index, Bath AS Functional Index). 18050373 2007
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis
0.100 Biomarker disease BEFREE To find out whether disease activity and B27 status were associated with serum concentrations of IgA, C reactive protein (CRP), and haptoglobin in ankylosing spondylitis (AS) multivariate analysis of variance was used to study 101 patients with AS whose disease was clinically classified as active or inactive, and who were HLA-B27 typed. 2015008 1991
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis
0.100 Biomarker disease BEFREE Erythrocyte sedimentation rate, C-reactive protein, and ASDAS correlated with MRI inflammatory scores in nr-axSpA but not in AS. sCTX-I correlated with MRI-determined SIJ inflammatory scores in AS only. 27974096 2017
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis
0.100 Biomarker disease BEFREE Soluble TNFRI levels correlate with ESR and CRP in AS. 20595269 2010
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis
0.100 Biomarker disease BEFREE Demographic, clinical, disease activity (Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), Bath Ankylosing Spondylitis Functional Index (BASFI), erythrocyte sedimentation rate (ESR), and C-reactive protein (CRP)), and radiographic data (Bath Ankylosing Spondylitis Radiology Index (BASRI) score) were compared regarding HLA-B27 status. 30285828 2018