|
Sepsis
|
0.300 |
Biomarker
|
disease |
BEFREE |
CSF protein levels were 0.89 g/l (SD 0.37) in neonates without fever or elevated CRP (n = 26) and not significantly different from neonates with possible sepsis (n = 218) with 0.92 g/l (SD 0.40).
|
29540199 |
2018 |
|
Sepsis
|
0.300 |
Biomarker
|
disease |
BEFREE |
Between 2012 and 2015, PCT use among sepsis discharges increased six-fold while lactate and CRP use remained unchanged.
|
30332466 |
2018 |
|
Sepsis
|
0.300 |
Biomarker
|
disease |
BEFREE |
Presepsin and resistin had similar performance as CRP and PCT for the diagnosis of infection (best cut-off of 1444 pg/ml and 20 ng/ml, respectively) and sepsis.
|
31221548 |
2019 |
|
Sepsis
|
0.300 |
Biomarker
|
disease |
BEFREE |
In these patients, median (interquartile range) LBP (41.8 [41.1] µg/dL vs. 26.2 [25] µg/dL), CRP (240 [205] mg/L vs. 160 [148] mg/dL) and PCT (5.19 [13.68] µg/L vs. 0.39 [1.09] µg/L) were significantly higher than in patients classified as not having sepsis ( P < 0.001 for all three biomarkers).
|
28135842 |
2018 |
|
Sepsis
|
0.300 |
AlteredExpression
|
disease |
BEFREE |
To evaluate the PCT and CRP levels in 72 h at the onset of sepsis in GN and GP bacteremia.
|
27139197 |
2017 |
|
Sepsis
|
0.300 |
Biomarker
|
disease |
BEFREE |
The aims of the present meta-analysis were to assess the overall diagnostic accuracy of presepsin in pediatric sepsis and compare it to those for C-reactive protein (CRP) and procalcitonin (PCT).
|
31470804 |
2019 |
|
Sepsis
|
0.300 |
Biomarker
|
disease |
RGD |
A model of experimental acute hematogenous pyelonephritis in the rat.
|
21797109 |
2011 |
|
Sepsis
|
0.300 |
AlteredExpression
|
disease |
BEFREE |
Serum sCD18 levels partitioned sepsis non-survivors into one group of 'high' sCD18 and low CRP and another group with 'low' sCD18 and high C-reactive protein.
|
28714582 |
2017 |
|
Sepsis
|
0.300 |
Biomarker
|
disease |
BEFREE |
Positive post-test probability for any combinations of simultaneously analyzed CRP, PCT and CD64 showed improved diagnostic accuracy for sepsis.
|
28898742 |
2018 |
|
Sepsis
|
0.300 |
Biomarker
|
disease |
BEFREE |
Several serum-based biomarkers such as C-reactive protein, lactate, presepsin, and cytokines, such as interleukin-1 (IL-1), and IL-6 have been evaluated as early indicators of sepsis but none have been proven sensitive and/or specific enough to make a definitive diagnosis.
|
31323346 |
2019 |
|
Sepsis
|
0.300 |
Biomarker
|
disease |
BEFREE |
Circulating concentrations of the sensitive inflammatory marker C-reactive protein (CRP) predict future cardiovascular events, and CRP is elevated during sepsis and inflammation, when vascular reactivity may be modulated.
|
15795363 |
2005 |
|
Sepsis
|
0.300 |
Biomarker
|
disease |
BEFREE |
The results of this study suggest that IL-6 is better than PCT and CRP in predicting the treatment success in predominantly non-surgical sepsis in the first 48-72 h.
|
30760225 |
2019 |
|
Sepsis
|
0.300 |
Biomarker
|
disease |
BEFREE |
Concentrations of these biomarkers in function of sepsis severity (sepsis n = 94 and septic shock n = 21) and outcome (lethal n = 40, recovery n = 75) were tested, as well as correlations with APACHE II and SOFA scores, immunoglobulins, complement, PCT and CRP concentrations.
|
30142533 |
2018 |
|
Sepsis
|
0.300 |
Biomarker
|
disease |
BEFREE |
The aim of our study is to explore the value of soluble cluster of differentiation 14 subtype (sCD14-ST) in whole blood for differential diagnosis of neonatal hematosepsis at an early stage, and used in evaluation of the severity about sepsis combined with acute physiology and chronic health evaluation II (APACHE-II) score, procalcitonin (PCT), C reactive protein (CRP), and leukocyte (WBC).In our cohort, all cases met the diagnostic criteria for hematosepsis specific for newborns.
|
28471985 |
2017 |
|
Sepsis
|
0.300 |
Biomarker
|
disease |
BEFREE |
Several lines of evidences suggest that PSP has a higher diagnostic performance for the identification of sepsis than procalcitonin and C-reactive protein, and a strong prognostic value to predict unfavorable outcome at admission to intensive care unit.
|
30672312 |
2019 |
|
Sepsis
|
0.300 |
GeneticVariation
|
disease |
BEFREE |
Death was the primary outcome in only one study and a survival benefit was not observed in the subset specified as sepsis (10 RCTs; RR, 0.94; 95% CI, 0.85-1.03; I<sup>2</sup> = 0%), those without industry sponsorship (nine RCTs; RR, 0.98; 95% CI, 0.87-1.10; I<sup>2</sup> = 0%), high PCT-guided algorithm adherence (five RCTs; RR, 0.93; 95% CI, 0.71-1.22; I<sup>2</sup> = 0%), and PCT-guided algorithms without C-reactive protein (eight RCTs; RR, 0.96; 95% CI, 0.87-1.06; I<sup>2</sup> = 0%).
|
30772386 |
2019 |
|
Sepsis
|
0.300 |
AlteredExpression
|
disease |
BEFREE |
<b>Conclusion</b> The CRP levels and heart rate both decreased, while the pH and base excess parameters of the blood gas analysis changed positively after pentoxifylline treatment in VLBW preterm neonates with nosocomial sepsis.
|
28196391 |
2017 |
|
Sepsis
|
0.300 |
Biomarker
|
disease |
BEFREE |
The prognostic value of bioscore and SOFA was similar for predicting 90-day mortality.<b>Conclusions:</b> The new bioscore formed by combination of CRP, PCT and SOFA score may be useful in early diagnosis of sepsis.
|
31687850 |
2019 |
|
Sepsis
|
0.300 |
AlteredExpression
|
disease |
BEFREE |
Mechanical ventilation, white blood cell (WBC) counts, C-reactive protein (CRP) and lactate levels, maximum 24-h APACHE-II scores, and AGP concentrations were significantly higher upon admission in patients with sepsis who died.
|
31309103 |
2019 |
|
Sepsis
|
0.300 |
Biomarker
|
disease |
BEFREE |
In both CKD1-4 and CKD5 patients, the predictive value of PCT for local infection is not as good as that of CRP, while it has a significant advantage in predicting sepsis.
|
28956241 |
2017 |
|
Sepsis
|
0.300 |
Biomarker
|
disease |
BEFREE |
Toward Early Diagnosis of Late-Onset Sepsis in Preterm Neonates: Dual Magnetoimmunosensor for Simultaneous Procalcitonin and C-Reactive Protein Determination in Diagnosed Clinical Samples.
|
31305070 |
2019 |
|
Sepsis
|
0.300 |
GeneticVariation
|
disease |
BEFREE |
We evaluated the impact of an automatic stop order (ASO) and C-reactive protein (CRP) on the duration of antibiotics and level of intervention in infants screened for early-onset sepsis who had negative cultures.
|
28155332 |
2018 |
|
Sepsis
|
0.300 |
Biomarker
|
disease |
BEFREE |
Significant differences in NLCR values were observed between sepsis and non-sepsis patients (15.3 [10.8-38.2] (median [interquartile range] vs. 9.3 [6.2-14.5]; P<0.001), as well as for CRP level, PCT level and lymphocyte count.
|
30811475 |
2019 |
|
Sepsis
|
0.300 |
Biomarker
|
disease |
BEFREE |
Based on the results of our meta-analysis, presepsin is a promising marker for diagnosis of sepsis as PCT or CRP, but its results should be interpreted more carefully and cautiously since too few studies were included and those studies had high heterogeneity between them.
|
28875483 |
2017 |
|
Sepsis
|
0.300 |
Biomarker
|
disease |
BEFREE |
The application of PCT to predict local infection in patients with T2DM was identified to be inferior to CRP, but its ability to predict sepsis was concluded to be the best when compared with CRP, white blood cell count and neutrophil percent.
|
31258707 |
2019 |