|
Sepsis
|
0.300 |
Biomarker
|
disease |
BEFREE |
Nevertheless, combination of low CD64 index with low CRP concentrations on day 1 ruled out sepsis except in three patients.
|
27648690 |
2017 |
|
Sepsis
|
0.300 |
AlteredExpression
|
disease |
BEFREE |
To compute diagnostic test properties of C-reactive protein (CRP) and serum procalcitonin (PCT) levels in bloodstream infections in children with cancer and suspected sepsis, in comparison with blood culture as the gold standard.
|
28504925 |
2017 |
|
Sepsis
|
0.300 |
Biomarker
|
disease |
BEFREE |
IDO and kynurenine showed a strong positive correlation with markers of infection (procalcitonin) and inflammation (C-reactive protein) as well as sepsis and CAP severity scores.
|
28076309 |
2017 |
|
Sepsis
|
0.300 |
GeneticVariation
|
disease |
BEFREE |
The rs1764390 G allele is associated with increased susceptibility to sepsis, which may be involved in the process of sepsis via mediating the plasma levels of NO, IL-6 and CRP.
|
27939333 |
2017 |
|
Sepsis
|
0.300 |
Biomarker
|
disease |
BEFREE |
Comparison of procalcitonin and high-sensitivity C-reactive protein for the diagnosis of sepsis and septic shock in the oldest old patients.
|
28764651 |
2017 |
|
Sepsis
|
0.300 |
Biomarker
|
disease |
BEFREE |
Procalcitonin (PCT), neutrophil-lymphocyte count ratio (NLCR), C-reactive protein (CRP), and lactate were determined in a total of 1,572 episodes of adult patients admitted to the emergency department on suspicion of sepsis.
|
28727802 |
2017 |
|
Sepsis
|
0.300 |
Biomarker
|
disease |
BEFREE |
The severity of sepsis (tachycardia and CRP ≥150 mg/mL) and of imaging signs (pneumoperitoneum ≥5 mm and peritoneal fluid in the pouch of Douglas) were risk factors for medical treatment failure of PDwAP requiring special supervision so as not to lose time in undertaking surgical management.
|
28258453 |
2017 |
|
Sepsis
|
0.300 |
AlteredExpression
|
disease |
BEFREE |
Median CRP, PCT and presepsin levels were significantly higher in patients with infection and sepsis.
|
27823951 |
2017 |
|
Sepsis
|
0.300 |
Biomarker
|
disease |
BEFREE |
We concluded that CRP dosage at hospital admission is helpful to detect acute infection, and particularly sepsis, in geriatric patients, and that CRP elevation may provide valuable short-term prognostic information.
|
27594414 |
2017 |
|
Sepsis
|
0.300 |
Biomarker
|
disease |
BEFREE |
Biomarker (procalcitonin, white blood cells and platelet countings, prothrombinemia, D-dimers, C-reactive protein, blood lactate and temperature) values were available for 48 patients without sepsis (2767 timepoints) and 102 patients with sepsis (652 timepoints).
|
28454850 |
2017 |
|
Sepsis
|
0.300 |
Biomarker
|
disease |
BEFREE |
In a logistic regression analysis including TRX, C-reactive protein, injury severity, massive transfusion, and admission blood pressure, TRX was the only variable independently associated with post-injury sepsis.
|
28087409 |
2017 |
|
Sepsis
|
0.300 |
Biomarker
|
disease |
BEFREE |
The levels of hemoglobin, white blood cell, platelet, lactate, and C-reactive protein were measured in the blood samples drawn from the patients with sepsis at diagnosis, at the 48th hour, and on day 7.
|
28167245 |
2017 |
|
Sepsis
|
0.300 |
AlteredExpression
|
disease |
BEFREE |
Serum levels of calprotectin and C-reactive protein were significantly higher in patients with melioidosis and nonmelioidosis sepsis than in healthy controls.
|
28179407 |
2017 |
|
Sepsis
|
0.300 |
Biomarker
|
disease |
BEFREE |
In this study, we examined the time course changes in the blood levels of HMGB1, C-reactive protein (CRP), procalcitonin (PCT) and serum amyloid A (SAA) in patients with secondary peritonitis who developed SIRS or sepsis.
|
28680349 |
2017 |
|
Sepsis
|
0.300 |
AlteredExpression
|
disease |
BEFREE |
In univariate analyses, higher age (p = 0.04), higher levels of C-reactive protein (p < 0.001), etiology of PRES (sepsis and chemotherapy; p = 0.02), altered coagulation (p = 0.002), altered mental state at onset (p = 0.03), and subarachnoid hemorrhage (SAH; p = 0.01) were related to in-hospital death.
|
27815684 |
2017 |
|
Sepsis
|
0.300 |
Biomarker
|
disease |
BEFREE |
A high negative predictive value of CRP is also needed to rule out sepsis and bacterial infections in immunocompetent patients.
|
28735154 |
2017 |
|
Sepsis
|
0.300 |
Biomarker
|
disease |
BEFREE |
We show that the sensitivity of sMR to predict mortality [area under curve (AUC) = 0.77] exceeded the sensitivity of procalcitonin (PCT, AUC = 0.63), C-reactive protein (CRP, AUC = 0.61) and the macrophage soluble receptor, CD163 (sCD163, AUC = 0.74), while it was less accurate to predict diagnosis of sepsis [AUC(sMR) = 0.69 vs. AUC(PCT) = 0.79, AUC(CRP) = 0.71 and AUC(sCD163) = 0.66].
|
29383956 |
2018 |
|
Sepsis
|
0.300 |
Biomarker
|
disease |
BEFREE |
We specified PCT and CRP cut-off values with high PPV and NPV for revealing the presence of bacterial infection and sepsis in HD patients.
|
29717808 |
2018 |
|
Sepsis
|
0.300 |
GeneticVariation
|
disease |
BEFREE |
CONCLUSIONS Our study suggests that rs1205 genetic variability in the CRP gene determines the CRP levels in sepsis of different severities, while SNP rs3091244 and SNP rs2808630 are not associated with sepsis.
|
29379005 |
2018 |
|
Sepsis
|
0.300 |
Biomarker
|
disease |
BEFREE |
Serum levels of C-reactive protein (CRP) as biomarker endpoint and recovery of sepsis as clinical endpoint were used to compare treatment responses between groups.
|
30012383 |
2018 |
|
Sepsis
|
0.300 |
GeneticVariation
|
disease |
BEFREE |
Sepsis-3 (subdistribution HR (sHR)=5.47; p=0.006), qSOFA (sHR=1.99; p=0.020), Chronic Liver Failure Consortium Acute Decompensation score (sHR=1.05; p=0.001) and C reactive protein (sHR=1.01;p=0.034) were found to be independent predictors of in-hospital mortality.
|
28860348 |
2018 |
|
Sepsis
|
0.300 |
Biomarker
|
disease |
BEFREE |
This study revealed the superiority of colistin-meropenem combination therapy over colistin monotherapy in the treatment of MDR K. pneumoniae-induced HAP or VAP and highlights the advantage of procalcitonin over CRP as a marker for eradication of sepsis and suspension of therapy.
|
30010061 |
2018 |
|
Sepsis
|
0.300 |
Biomarker
|
disease |
BEFREE |
Multiple regression analyses showed independent associations of CRP with diagnosis of sepsis, and CRP and lactate with mortality.
|
29176018 |
2018 |
|
Sepsis
|
0.300 |
Biomarker
|
disease |
BEFREE |
CSF protein levels were 0.89 g/l (SD 0.37) in neonates without fever or elevated CRP (n = 26) and not significantly different from neonates with possible sepsis (n = 218) with 0.92 g/l (SD 0.40).
|
29540199 |
2018 |
|
Sepsis
|
0.300 |
Biomarker
|
disease |
BEFREE |
Between 2012 and 2015, PCT use among sepsis discharges increased six-fold while lactate and CRP use remained unchanged.
|
30332466 |
2018 |