Autism Spectrum Disorders
|
0.310 |
Biomarker
|
disease |
CTD_human |
Allowing for sex differences increases power in a GWAS of multiplex Autism families.
|
21151189 |
2012 |
Autism Spectrum Disorders
|
0.310 |
Biomarker
|
disease |
BEFREE |
The SNPs of genes such as RYR2, UPP2, and the androgen receptor gene have been shown to have sex-biasing factors in both girls and boys diagnosed with ASD.
|
26781567 |
2017 |
Major Depressive Disorder
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
The International SSRI Pharmacogenomics Consortium (ISPC): a genome-wide association study of antidepressant treatment response.
|
25897834 |
2015 |
TARSAL-CARPAL COALITION SYNDROME
|
0.020 |
AlteredExpression
|
disease |
BEFREE |
UP-II gene-expression was detected in the peripheral blood from all three patients with metastatic TCC but not from the nine patients with non-metastatic TCC nor the three healthy volunteers.
|
10404304 |
1999 |
TARSAL-CARPAL COALITION SYNDROME
|
0.020 |
Biomarker
|
disease |
BEFREE |
Immunohistochemical staining using rabbit antisera against a synthetic peptide of UP-II and against total UPs showed UP reactivity in 39.5% (17 of 43 cases) of conventional TCCs, 12.8% (5 of 39) of bilharzial-related TCCs, and 2.7% (1 of 36) of bilharzial-related squamous cell carcinomas (SCCs).
|
9515818 |
1998 |
Autistic Disorder
|
0.010 |
Biomarker
|
disease |
BEFREE |
A second gene, uridine phosphorylase 2, with a joint P-value of 2.3E-9, has been previously linked and associated with Autism in independent samples.
|
21151189 |
2012 |
Squamous cell carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Immunohistochemical staining using rabbit antisera against a synthetic peptide of UP-II and against total UPs showed UP reactivity in 39.5% (17 of 43 cases) of conventional TCCs, 12.8% (5 of 39) of bilharzial-related TCCs, and 2.7% (1 of 36) of bilharzial-related squamous cell carcinomas (SCCs).
|
9515818 |
1998 |
Carcinoma, Transitional Cell
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
A survey of 50 transitional cell carcinomas (TCCs) revealed a UP-II polymorphism but no tumor-specific mutations.
|
9515818 |
1998 |
Diabetes
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Incident self-reported diabetes cases were identified at follow-up II interview (2006-2010).
|
29021814 |
2017 |
Diabetes Mellitus, Non-Insulin-Dependent
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Incident self-reported T2D cases were identified at follow-up II interview (2006-2010).
|
28448891 |
2017 |
Sudden Cardiac Death
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.
|
21658281 |
2011 |
Sudden Cardiac Arrest
|
0.100 |
GeneticVariation
|
phenotype |
GWASDB |
GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.
|
21658281 |
2011 |
response to SSRI
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
The International SSRI Pharmacogenomics Consortium (ISPC): a genome-wide association study of antidepressant treatment response.
|
25897834 |
2015 |
Neoplasm Metastasis
|
0.010 |
AlteredExpression
|
phenotype |
BEFREE |
UP II mRNA-positive cells were detected in 3 (10.3%) of 29 patients with superficial cancers (pTa-1N0M0), 4 (28.6%) of 14 patients with muscularly invasive cancers (pT2-4N0M0), 2 (40.0%) of 5 loco-regional node-positive patients (pN1-2M0), and 6 (75.0%) of 8 patients with distant metastases.
|
10955799 |
2000 |
Malignant Neoplasms
|
0.010 |
AlteredExpression
|
group |
BEFREE |
UP II mRNA-positive cells were detected in 3 (10.3%) of 29 patients with superficial cancers (pTa-1N0M0), 4 (28.6%) of 14 patients with muscularly invasive cancers (pT2-4N0M0), 2 (40.0%) of 5 loco-regional node-positive patients (pN1-2M0), and 6 (75.0%) of 8 patients with distant metastases.
|
10955799 |
2000 |
Diabetes Mellitus
|
0.010 |
GeneticVariation
|
group |
BEFREE |
Incident self-reported diabetes cases were identified at follow-up II interview (2006-2010).
|
29021814 |
2017 |
Neoplasms
|
0.010 |
Biomarker
|
group |
BEFREE |
These results suggest that our nested reverse transcription-PCR assay for UP II is highly specific and might be used as a tumor marker for molecular staging of urothelial cancers, although the sensitivity is not so optimal.
|
10955799 |
2000 |
Secondary Neoplasm
|
0.010 |
AlteredExpression
|
group |
BEFREE |
UP II mRNA-positive cells were detected in 3 (10.3%) of 29 patients with superficial cancers (pTa-1N0M0), 4 (28.6%) of 14 patients with muscularly invasive cancers (pT2-4N0M0), 2 (40.0%) of 5 loco-regional node-positive patients (pN1-2M0), and 6 (75.0%) of 8 patients with distant metastases.
|
10955799 |
2000 |