Hepatitis, Toxic
|
0.200 |
Therapeutic
|
disease |
CTD_mouse |
Cytochrome P450 2A5 and bilirubin: mechanisms of gene regulation and cytoprotection.
|
23628428 |
2013 |
Hepatoma, Morris
|
0.200 |
Biomarker
|
disease |
CTD_mouse |
Expression profiling and identification of novel genes in hepatocellular carcinomas.
|
11420682 |
2001 |
Hepatoma, Novikoff
|
0.200 |
Biomarker
|
disease |
CTD_mouse |
Expression profiling and identification of novel genes in hepatocellular carcinomas.
|
11420682 |
2001 |
Experimental Hepatoma
|
0.200 |
Biomarker
|
disease |
CTD_mouse |
Expression profiling and identification of novel genes in hepatocellular carcinomas.
|
11420682 |
2001 |
Hepatitis, Drug-Induced
|
0.200 |
Therapeutic
|
disease |
CTD_mouse |
Cytochrome P450 2A5 and bilirubin: mechanisms of gene regulation and cytoprotection.
|
23628428 |
2013 |
Drug-Induced Acute Liver Injury
|
0.200 |
Therapeutic
|
disease |
CTD_mouse |
Cytochrome P450 2A5 and bilirubin: mechanisms of gene regulation and cytoprotection.
|
23628428 |
2013 |
Chemical and Drug Induced Liver Injury
|
0.200 |
Therapeutic
|
disease |
CTD_mouse |
Cytochrome P450 2A5 and bilirubin: mechanisms of gene regulation and cytoprotection.
|
23628428 |
2013 |
Chemically-Induced Liver Toxicity
|
0.200 |
Therapeutic
|
disease |
CTD_mouse |
Cytochrome P450 2A5 and bilirubin: mechanisms of gene regulation and cytoprotection.
|
23628428 |
2013 |
Malignant neoplasm of breast
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
These include four loci that were associated (unadjusted P<0.05) with breast cancer (GTF2H2, ZNF385B, NAALADL2 and PSG5), and two loci associated with ovarian cancer (CYP2A7 and OR2A1).
|
28145423 |
2017 |
Glioblastoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
To this end, we evaluated the STAT3-inhibitory activities of three compounds (CPA-7 [trichloronitritodiammineplatinum(IV)], WP1066 [(S,E)-3-(6-bromopyridin-2-yl)-2-cyano-N-(1-phenylethyl)acrylamide, C17H14BrN3O], and ML116 [4-benzyl-1-{thieno[2,3-d]pyrimidin-4-yl}piperidine, C18H19N3S]) in cultured rodent and human glioma cells, including GBM cancer stem cells.
|
24696041 |
2014 |
Hepatitis C
|
0.010 |
Biomarker
|
disease |
BEFREE |
We found that the naive CTL repertoire of both groups contains cross-reactive CTLs inducible by the HCV peptide recognizing both CYP2A6 and CYP2A7 peptides as well as endogenously processed CYP2A6 protein.
|
10432280 |
1999 |
Chronic Obstructive Airway Disease
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Previously reported associations on chromosome 19 showed suggestive and directionally consistent associations among common variants (RAB4, CYP2A7, and CYP2B6) and for rare variants (CYP2A7) among COPDGene NHW subjects.
|
29767774 |
2019 |
Myotonic Dystrophy
|
0.010 |
Biomarker
|
disease |
BEFREE |
Localisation of CYP2A on a panel of somatic cell hybrids also suggests that it is proximal to DM and APOC2/C1/E gene cluster.
|
1975560 |
1990 |
Adenomatous Polyposis Coli
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Chromosome 19q13 disruption alters expressions of CYP2A7, MIA and MIA-RAB4B lncRNA and contributes to FAP-like phenotype in APC mutation-negative familial colorectal cancer patients.
|
28306719 |
2017 |
Atrial Premature Complexes
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Chromosome 19q13 disruption alters expressions of CYP2A7, MIA and MIA-RAB4B lncRNA and contributes to FAP-like phenotype in APC mutation-negative familial colorectal cancer patients.
|
28306719 |
2017 |
Breast Carcinoma
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
These include four loci that were associated (unadjusted P<0.05) with breast cancer (GTF2H2, ZNF385B, NAALADL2 and PSG5), and two loci associated with ovarian cancer (CYP2A7 and OR2A1).
|
28145423 |
2017 |
ovarian neoplasm
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
These include four loci that were associated (unadjusted P<0.05) with breast cancer (GTF2H2, ZNF385B, NAALADL2 and PSG5), and two loci associated with ovarian cancer (CYP2A7 and OR2A1).
|
28145423 |
2017 |
Malignant neoplasm of ovary
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
These include four loci that were associated (unadjusted P<0.05) with breast cancer (GTF2H2, ZNF385B, NAALADL2 and PSG5), and two loci associated with ovarian cancer (CYP2A7 and OR2A1).
|
28145423 |
2017 |
Familial (FPAH)
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Chromosome 19q13 disruption alters expressions of CYP2A7, MIA and MIA-RAB4B lncRNA and contributes to FAP-like phenotype in APC mutation-negative familial colorectal cancer patients.
|
28306719 |
2017 |
Glioblastoma Multiforme
|
0.010 |
Biomarker
|
disease |
BEFREE |
To this end, we evaluated the STAT3-inhibitory activities of three compounds (CPA-7 [trichloronitritodiammineplatinum(IV)], WP1066 [(S,E)-3-(6-bromopyridin-2-yl)-2-cyano-N-(1-phenylethyl)acrylamide, C17H14BrN3O], and ML116 [4-benzyl-1-{thieno[2,3-d]pyrimidin-4-yl}piperidine, C18H19N3S]) in cultured rodent and human glioma cells, including GBM cancer stem cells.
|
24696041 |
2014 |
Liver carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
In summary, our results confirmed for the first time that a four-CYP gene (CYP1A2, CYP2E1, CYP2A7, and PTGIS) signature is associated with fast-growing HCC, and CYP2C8 is associated with patient survival.
|
30971588 |
2020 |
AMYLOIDOSIS, HEREDITARY, TRANSTHYRETIN-RELATED
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Chromosome 19q13 disruption alters expressions of CYP2A7, MIA and MIA-RAB4B lncRNA and contributes to FAP-like phenotype in APC mutation-negative familial colorectal cancer patients.
|
28306719 |
2017 |
Carcinoma, Ovarian Epithelial
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
These include four loci that were associated (unadjusted P<0.05) with breast cancer (GTF2H2, ZNF385B, NAALADL2 and PSG5), and two loci associated with ovarian cancer (CYP2A7 and OR2A1).
|
28145423 |
2017 |
Liver Neoplasms, Experimental
|
0.200 |
Biomarker
|
phenotype |
CTD_mouse |
Expression profiling and identification of novel genes in hepatocellular carcinomas.
|
11420682 |
2001 |
Drug-Induced Liver Disease
|
0.200 |
Therapeutic
|
phenotype |
CTD_mouse |
Cytochrome P450 2A5 and bilirubin: mechanisms of gene regulation and cytoprotection.
|
23628428 |
2013 |