|
Left Ventricular Hypertrophy
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
In the present study, we examined the possibility that the genotype of the ACE gene might influence the development of left ventricular hypertrophy.
|
7994801 |
1994 |
|
Left Ventricular Hypertrophy
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
The ACE genotype was associated neither with left ventricular mass nor with the prevalence of left ventricular hypertrophy.
|
8598840 |
1996 |
|
Left Ventricular Hypertrophy
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
The deletion/insertion (D/I) polymorphism of the angiotensin-converting enzyme gene is associated with hypertension in men, left ventricular hypertrophy in untreated hypertensive patients, various atherosclerotic cardiovascular complications, and microvascular disorders.
|
11134677 |
2000 |
|
Left Ventricular Hypertrophy
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
A weaker renal function dependent association between the ACE I/D polymorphism and LVH was also observed.
|
17903694 |
2007 |
|
Left Ventricular Hypertrophy
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
The association of LV hypertrophy with ACE gene insertion/deletion (I/D) polymorphism was analyzed.
|
15799176 |
2004 |
|
Left Ventricular Hypertrophy
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
The DD genotype of the ACE-gene is associated with an increased left ventricular mass and with a significantly higher prevalence of eccentric left ventricular hypertrophy, when compared to ID genotype.
|
10536704 |
1999 |
|
Left Ventricular Hypertrophy
|
0.600 |
GeneticVariation
|
disease |
LHGDN |
(3) There is a synergistic effect between the polymorphism of ACE gene and CYP11B2 gene to result in LVH in EH.
|
12133420 |
2002 |
|
Left Ventricular Hypertrophy
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Polymorphism of the AGT M235T gene but not ACE I/D gene is associated with greater LVMi and relative wall thickness, indicating more concentric LVH, in Chinese peritoneal dialysis patients.
|
12675870 |
2003 |
|
Left Ventricular Hypertrophy
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
The aim of the study was to analyze factors, including angiotensin-converting enzyme (ACE) genotype that may have an effect on the development of LVH in hemodialysis patients.
|
10657713 |
2000 |
|
Left Ventricular Hypertrophy
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Serum ACE activity and plasma concentrations of brain natriuretic peptide, a marker for left ventricular hypertrophy, were also monitored.
|
10335726 |
1999 |
|
Left Ventricular Hypertrophy
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
These data suggest that the DD genotype of the ACE gene polymorphism is a contributory factor for the development of LV hypertrophy in patients with end-stage renal disease (ESRD).
|
9820440 |
1998 |
|
Left Ventricular Hypertrophy
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Relationship between the angiotensin converting enzyme gene polymorphism and the effects of enalapril on left ventricular hypertrophy and impaired diastolic filling in essential hypertension: M-mode and pulsed Doppler echocardiographic studies.
|
8986921 |
1996 |
|
Left Ventricular Hypertrophy
|
0.600 |
Biomarker
|
disease |
BEFREE |
Also, ACE and the 12 other genotypes did not affect risk of the primary composite endpoint or its components stroke, myocardial infarction, and cardiovascular death, or treatment differences between losartan and atenolol on these endpoints, as assessed by Cox proportional hazards models including baseline Framingham risk score and LVH.
|
20065889 |
2010 |
|
Left Ventricular Hypertrophy
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Angiotensin-converting enzyme insertion/deletion polymorphism, 24-h blood pressure profile and left ventricular hypertrophy in hypertensive individuals: a cross-sectional study.
|
26336879 |
2015 |
|
Left Ventricular Hypertrophy
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
The study investigated whether the insertion/deletion (I/D) polymorphism of ACE gene and the A/B polymorphism of the CMA gene are related to the regression of LVH in essential hypertension patients who were participants in a long-term trial of therapy with benazepril.
|
15788353 |
2005 |
|
Left Ventricular Hypertrophy
|
0.600 |
Biomarker
|
disease |
BEFREE |
Of the five candidate gene markers studied, no significant differences in the genotype distribution of the MTHFR, PON 1 and 2 or ACE markers were found between the LVH and non-LVH groups.
|
11768721 |
2001 |
|
Left Ventricular Hypertrophy
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Angiotensin-converting enzyme gene polymorphism and reversibility of uremic left ventricular hypertrophy following long-term antihypertensive therapy.
|
9690230 |
1998 |
|
Left Ventricular Hypertrophy
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
1.The relationship between the angiotensinogen (AGT) T174M, angiotensin converting enzyme (ACE) insertion/deletion (I/D) and the angiotensin II type 1 receptor (AT1) genetic markers and left ventricular hypertrophy was examined in normal subjects and those with aortic stenosis.2.
|
8800593 |
1996 |
|
Left Ventricular Hypertrophy
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Furthermore, neither ID ACE-gene polymorphism nor ATI-receptor gene and angiotensinogen gene polymorphism was associated with LVH.
|
11688760 |
2001 |
|
Left Ventricular Hypertrophy
|
0.600 |
GeneticVariation
|
disease |
LHGDN |
The aim of the study was to evaluate the prevalence of hypertension, left ventricular hypertrophy, hypertensive retinopathy in patients treated with haemodialysis and to evaluate the association between the polymorphism of RAAS genes: ACE I/D, AGT M235T AT1R A1166C, CYP112 (-344) and the systemic complications of arterial hypertension such as hypertensive retinopathy, left ventricular hypertrophy and also mortality in haemodialysis patients.
|
19112833 |
2008 |
|
Left Ventricular Hypertrophy
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
The effect of angiotensin receptor blockade ARB on the regression of left ventricular hypertrophy in hemodialysis patients: comparison between patients with D allele and non-D allele ACE gene polymorphism.
|
16312263 |
2005 |
|
Left Ventricular Hypertrophy
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
The association of ACE gene insertion/deletion polymorphisms with LVH was assessed by chi-squared test.
|
31064975 |
2019 |
|
Left Ventricular Hypertrophy
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
In contrast to some previous studies, we have found in this group of previously untreated hypertensive subjects no evidence to suggest that the deletion polymorphism of the ACE genotype is important in the development of LVH.
|
9364280 |
1997 |
|
Left Ventricular Hypertrophy
|
0.600 |
Biomarker
|
disease |
CTD_human |
Systolic blood pressure, plasma renin activity, and cardiac angiotensin converting enzyme activity of L-NAME rats with left ventricular hypertrophy were significantly higher than those of the subgroup without.(ABSTRACT TRUNCATED AT 250 WORDS)
|
8349331 |
1993 |
|
Left Ventricular Hypertrophy
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
DNA analysis of the ACE gene deletion polymorphism showed those with the deletion/deletion (D/D) genotype had a greater progression of left ventricular hypertrophy compared to those carrying the other ACE genotypes (increase in hypertrophy: 6.2 +/- 3.3 vs. 1.7 +/- 4.2 mm; p < 0.01, D/D vs. I/D genotype; 2.8 +/- 5.8 mm; p = ns, D/D vs. I/I genotype).
|
15314809 |
2004 |