CFD, complement factor D, 1675

N. diseases: 83; N. variants: 4
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0398764
Disease: Complement Factor D Deficiency
Complement Factor D Deficiency 		0.700 Biomarker disease CTD_human
CUI: C0398764
Disease: Complement Factor D Deficiency
Complement Factor D Deficiency 		0.700 CausalMutation disease CLINVAR
CUI: C0272242
Disease: Complement deficiency disease
Complement deficiency disease 		0.400 Biomarker group HPO
CUI: C1844383
Disease: Recurrent bacterial infection
Recurrent bacterial infection 		0.100 Biomarker phenotype HPO
CUI: C1861403
Disease: Variable expressivity
Variable expressivity 		0.100 Biomarker phenotype HPO
CUI: C0011603
Disease: Dermatitis
Dermatitis 		0.010 Biomarker disease BEFREE <b>Abbreviations:</b> atopic dermatitis: AD; interleukin: IL; persistent facial dermatitis: PFD; T-helper cell type 1: Th1; T-helper cell type 2: Th2; T-helper cell type 17: Th17; tumor necrosis factor-∝: TNF-∝. 31132923 2019
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease 		0.010 Biomarker disease BEFREE 3D: Three-dimensional; 3DR: Three-dimensional Reconstruction; 3D-QCA: Three-dimensional quantitative coronary angiography; ALWSS: Areas of low wall shear stress; CAD: Coronary artery disease; CFD: Computational fluid dynamics; %DS: Diameter stenosis percentage; EPCS: End point of counter-rotating streamlines; FSI: Fluid-structure interaction; IVUS: Intravascular ultrasound; LAD: Left anterior descending; MWSS: Maximum wall shear stress; SST: Shear stress transport; TAWSS: Time-averaged wall shear stress; WSS: wall shear stress; WPG: Wall pressure gradient; MWPG: Maximum wall pressure gradient; FFR: Fractional flow reserve; iFR: Instantaneous wave-free ratio. 27467730 2017
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.010 Biomarker disease BEFREE CFD was more accurate than CEA or CA19-9 in diagnosing CRC. 22975639 2013
CUI: C0010200
Disease: Coughing
Coughing 		0.020 Biomarker phenotype BEFREE CFD transient simulation of the cough clearance process using an Eulerian wall film model. 27380322 2017
CUI: C0152419
Disease: Interrupted aortic arch
Interrupted aortic arch 		0.010 Biomarker disease BEFREE CFD analysis in IAA can provide a clinical reference, and the results should be further studied in depth in the future. 31197221 2019
CUI: C0041296
Disease: Tuberculosis
Tuberculosis 		0.010 Biomarker disease BEFREE CFD simulations for paper-based DNA amplification reaction (LAMP) of Mycobacterium tuberculosis-point-of-care diagnostic perspective. 31845080 2020
CUI: C0332853
Disease: Anastomosis
Anastomosis 		0.010 Biomarker disease BEFREE A CFD study was carried out to clarify the reasons for the stagnation and to find favorable anastomosis methods from a fluid dynamical point of view. 31610882 2020
CUI: C0333099
Disease: Fusiform Aneurysm
Fusiform Aneurysm 		0.010 Biomarker disease BEFREE A comparative CFD analysis of common carotid fusiform aneurysm in canine models and vertebrobasilar fusiform aneurysm in human patients. 28945061 2018
CUI: C0003257
Disease: Antibody Deficiency Syndrome
Antibody Deficiency Syndrome 		0.300 Biomarker disease CTD_human A family with complement factor D deficiency. 11457876 2001
CUI: C0021051
Disease: Immunologic Deficiency Syndromes
Immunologic Deficiency Syndromes 		0.300 Biomarker group CTD_human A family with complement factor D deficiency. 11457876 2001
CUI: C0085396
Disease: Neisseriaceae Infections
Neisseriaceae Infections 		0.300 Biomarker group CTD_human A family with complement factor D deficiency. 11457876 2001
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma 		0.010 Biomarker disease BEFREE A total of 21 central node genes were identified as key genes in the PTC disease process including complement factor D (CFD), Collagen Type I α 1 Chain (COL1A1), Extracellular Matrix Protein 1 (ECM1) and Fibronectin 1 (FN1). 30344727 2018
CUI: C4732730
Disease: Blood spots
Blood spots 		0.010 Biomarker disease BEFREE A total of 2264 singletons and 1144 twins from Upstate KIDS (born 2008-2010) had adiponectin, leptin, resistin and complement factor D measured in newborn blood spots. 29781193 2018
CUI: C0398764
Disease: Complement Factor D Deficiency
Complement Factor D Deficiency 		0.700 Biomarker disease GENOMICS_ENGLAND A type III complement factor D deficiency: Structural insights for inhibition of the alternative pathway. 29522842 2018
CUI: C0272242
Disease: Complement deficiency disease
Complement deficiency disease 		0.400 Biomarker group GENOMICS_ENGLAND A type III complement factor D deficiency: Structural insights for inhibition of the alternative pathway. 29522842 2018
CUI: C0851883
Disease: Neisseria infection
Neisseria infection 		0.010 AlteredExpression disease BEFREE A young man suffering from recurrent Neisseria infections was shown to lack detectable serum complement factor D hemolytic activity. 2687330 1989
CUI: C0003949
Disease: Asbestosis
Asbestosis 		0.300 Biomarker disease CTD_human Adipokine adipsin is associated with the degree of lung fibrosis in asbestos-exposed workers. 22832039 2012
CUI: C0034069
Disease: Pulmonary Fibrosis
Pulmonary Fibrosis 		0.300 Biomarker disease CTD_human Adipokine adipsin is associated with the degree of lung fibrosis in asbestos-exposed workers. 22832039 2012
CUI: C2930617
Disease: Pulmonary Fibrosis - from Asbestos Exposure
Pulmonary Fibrosis - from Asbestos Exposure 		0.300 Biomarker disease CTD_human Adipokine adipsin is associated with the degree of lung fibrosis in asbestos-exposed workers. 22832039 2012
CUI: C4721507
Disease: Alveolitis, Fibrosing
Alveolitis, Fibrosing 		0.300 Biomarker disease CTD_human Adipokine adipsin is associated with the degree of lung fibrosis in asbestos-exposed workers. 22832039 2012