|
Premature Menopause
|
0.190 |
Biomarker
|
disease |
BEFREE |
Our breakpoint mapping data will help to identify additional candidate POF genes and to delineate the Xq POF critical region(s).
|
10894934 |
2000 |
|
Premature Menopause
|
0.190 |
Biomarker
|
disease |
BEFREE |
Our results indicated that DIAPH2 may be a polygenic pleiotropy for POF and AMD.
|
21386871 |
2011 |
|
Premature Menopause
|
0.190 |
GeneticVariation
|
disease |
BEFREE |
We found that a SNP (rs10521496) covered by DIAPH2, known to cause premature ovarian failure (POF) in females, is associated with age-related macular degeneration.
|
17549761 |
2007 |
|
Premature Menopause
|
0.190 |
Biomarker
|
disease |
BEFREE |
This comprehensive review first examines where and how the dogma of a finite pool was established, how this has been challenged over the years and addresses the most pertinent questions as to the current status of their existence, their role in female fertility, and perhaps most importantly, if they do exist, how can we harness these cells to improve a woman's oocyte reserve and treat conditions such as premature ovarian insufficiency (POI: also known as premature ovarian failure, POF).
|
28389520 |
2017 |
|
Premature Menopause
|
0.190 |
Biomarker
|
disease |
BEFREE |
Premature ovarian failure / primary ovarian insufficiency (POF/POI) associated with the mutations of the FMR1 (Fragile-X Mental Retardation 1) gene belongs to the group of the so-called trinucleotide expansion diseases.
|
29986653 |
2018 |
|
Premature Menopause
|
0.190 |
GeneticVariation
|
disease |
BEFREE |
Six deleterious variants in POF genes were also detected which might explain the pathogenesis of POF with abnormalities in the sex chromosomes.
|
27989800 |
2016 |
|
Premature Menopause
|
0.190 |
Biomarker
|
disease |
BEFREE |
We propose that the human DIA gene is one of the genes responsible for POF and that it affects the cell divisions that lead to ovarian follicle formation.
|
9497258 |
1998 |
|
Premature Menopause
|
0.190 |
AlteredExpression
|
disease |
BEFREE |
This was a cross-sectional survey of women with elevated follicle stimulating hormone levels with (premature ovarian failure or early menopause [POF/EM], n = 20) or without (diminished ovarian reserve [DOR], n = 20) amenorrhea.Seventy-five percent participated.
|
16522406 |
2006 |
|
Premature Menopause
|
0.190 |
Biomarker
|
disease |
BEFREE |
Previous studies have demonstrated that transplantation of hAECs effectively alleviate chemotherapy-induced ovarian damage via inhibiting granulose cells apoptosis in animal models of premature ovarian failure/insufficiency (POF/POI).
|
29179771 |
2017 |
|
Ovarian Failure, Premature
|
0.080 |
Biomarker
|
disease |
BEFREE |
Premature ovarian failure / primary ovarian insufficiency (POF/POI) associated with the mutations of the FMR1 (Fragile-X Mental Retardation 1) gene belongs to the group of the so-called trinucleotide expansion diseases.
|
29986653 |
2018 |
|
Ovarian Failure, Premature
|
0.080 |
GeneticVariation
|
disease |
BEFREE |
We found that a SNP (rs10521496) covered by DIAPH2, known to cause premature ovarian failure (POF) in females, is associated with age-related macular degeneration.
|
17549761 |
2007 |
|
Ovarian Failure, Premature
|
0.080 |
Biomarker
|
disease |
BEFREE |
We propose that the human DIA gene is one of the genes responsible for POF and that it affects the cell divisions that lead to ovarian follicle formation.
|
9497258 |
1998 |
|
Ovarian Failure, Premature
|
0.080 |
Biomarker
|
disease |
BEFREE |
Our results indicated that DIAPH2 may be a polygenic pleiotropy for POF and AMD.
|
21386871 |
2011 |
|
Ovarian Failure, Premature
|
0.080 |
Biomarker
|
disease |
BEFREE |
Mutations in MCM8/9 correlate principally with primary ovarian failure/insufficiency (POF/POI) and infertility indicating a meiotic defect.
|
30743181 |
2019 |
|
Ovarian Failure, Premature
|
0.080 |
Biomarker
|
disease |
BEFREE |
Our breakpoint mapping data will help to identify additional candidate POF genes and to delineate the Xq POF critical region(s).
|
10894934 |
2000 |
|
Ovarian Failure, Premature
|
0.080 |
Biomarker
|
disease |
BEFREE |
Previous studies have demonstrated that transplantation of hAECs effectively alleviate chemotherapy-induced ovarian damage via inhibiting granulose cells apoptosis in animal models of premature ovarian failure/insufficiency (POF/POI).
|
29179771 |
2017 |
|
Ovarian Failure, Premature
|
0.080 |
GeneticVariation
|
disease |
BEFREE |
Six deleterious variants in POF genes were also detected which might explain the pathogenesis of POF with abnormalities in the sex chromosomes.
|
27989800 |
2016 |
|
Mental disorders
|
0.040 |
Biomarker
|
group |
BEFREE |
Both the short screening questionnaire and the standardized interview from the DIA-X expert system were used for diagnosing mental disorders.
|
30416461 |
2018 |
|
Mental disorders
|
0.040 |
Biomarker
|
group |
BEFREE |
Addiction, DIA), and comorbid psychiatric disorders (Kiddie-Schedule for Affective Disorders and Schizophrenia-Present and Lifetime Version-Korean version, K-SADS-PL).
|
31261841 |
2019 |
|
Mental disorders
|
0.040 |
Biomarker
|
group |
BEFREE |
The computerized DIA-X CIDI Version 2.8 investigated in this study is an adaptation of the German DIA-X/Munich CIDI, which was translated in a multi-step process into Turkish and used to survey the prevalence of mental disorders in individuals with Turkish migration backgrounds in Germany (N = 662).
|
27766697 |
2017 |
|
Mental disorders
|
0.040 |
Biomarker
|
group |
BEFREE |
The Dominic Interactive for Adolescents-Revised (DIA-R) is a multimedia self-report screen for 9 mental disorders, borderline personality traits, and suicidality defined by the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders ( DSM-5).
|
27638424 |
2017 |
|
Desmoplastic infantile astrocytoma
|
0.030 |
Biomarker
|
disease |
BEFREE |
Desmoplastic infantile astrocytoma/ganglioglioma (DIA/DIG) are rare primary glioneuronal tumors that comprise 0.5% to 1.0% of all intracranial tumors.
|
29902580 |
2018 |
|
Desmoplastic infantile astrocytoma
|
0.030 |
Biomarker
|
disease |
BEFREE |
In the current study we evaluated automated DIA (D-Tek) for detecting autoantibodies related to autoimmune diseases of the gastrointestinal tract.
|
28522403 |
2017 |
|
Desmoplastic infantile astrocytoma
|
0.030 |
Biomarker
|
disease |
BEFREE |
Desmoplastic infantile astrocytoma/ganglioglioma (DIA/DIG) is a rare primary neuroepithelial brain tumour typically affecting paediatric patients younger than 24 months.
|
23822828 |
2014 |
|
Neoplasms
|
0.020 |
Biomarker
|
group |
BEFREE |
Desmoplastic infantile astrocytoma/ganglioglioma (DIA/DIG) are rare primary glioneuronal tumors that comprise 0.5% to 1.0% of all intracranial tumors.
|
29902580 |
2018 |