Bipolar Disorder
|
0.330 |
Biomarker
|
disease |
PSYGENET |
No association between the dihydropyrimidinase-related protein 2 (DRP-2) gene and bipolar disorder in humans.
|
12951196 |
2003 |
Bipolar Disorder
|
0.330 |
Biomarker
|
disease |
BEFREE |
No association between the dihydropyrimidinase-related protein 2 (DRP-2) gene and bipolar disorder in humans.
|
12951196 |
2003 |
Bipolar Disorder
|
0.330 |
Biomarker
|
disease |
PSYGENET |
We have previously demonstrated that the DRP-2 gene is associated with susceptibility to schizophrenia, but not to bipolar disorders.
|
17105906 |
2006 |
Bipolar Disorder
|
0.330 |
GeneticVariation
|
disease |
BEFREE |
We have previously demonstrated that the DRP-2 gene is associated with susceptibility to schizophrenia, but not to bipolar disorders.
|
17105906 |
2006 |
Bipolar Disorder
|
0.330 |
Biomarker
|
disease |
PSYGENET |
Various other protein products of genes associated with bipolar disorder either bind to or are affected by phosphatidyl-inositol phosphate products of this pathway (ADBRK2, HIP1R, KCNQ2, RGS4, WFS1), are associated with its constituent elements (BCR, DUSP6, FAT, GNAZ) or are downstream targets of this signalling cascade (DPYSL2, DRD3, GAD1, G6PD, GCH1, KCNQ2, NOS3, SLC6A3, SLC6A4, SST, TH, TIMELESS).
|
17239488 |
2007 |
Bipolar Disorder
|
0.330 |
Biomarker
|
disease |
PSYGENET |
Molecular genetics and developmental studies have identified 21 genes in this region (ADRA1A, ARHGEF10, CHRNA2, CHRNA6, CHRNB3, DKK4, DPYSL2, EGR3, FGF17, FGF20, FGFR1, FZD3, LDL, NAT2, NEF3, NRG1, PCM1, PLAT, PPP3CC, SFRP1 and VMAT1/SLC18A1) that are most likely to contribute to neuropsychiatric disorders (schizophrenia, autism, bipolar disorder and depression), neurodegenerative disorders (Parkinson's and Alzheimer's disease) and cancer.
|
19204725 |
2009 |
Bipolar Disorder
|
0.330 |
Biomarker
|
disease |
BEFREE |
Our results demonstrate that GSK3β and its substrate CRMP2 critically regulate the neurite structure of MSNs and their functions specifically within the indirect pathway of the basal ganglia network play a critical role in manifesting mania-like behavior of BD.
|
30699850 |
2019 |