Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis
0.100 GeneticVariation disease BEFREE The results suggested that the molecular variant of the angiotensinogen gene could be a new risk factor for coronary atherosclerosis. 7850980 1995
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis
0.100 GeneticVariation disease BEFREE Endothelial nitric oxide synthase and angiotensinogen gene polymorphism in coronary artery diseases in Egypt. 20547537 2011
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis
0.100 GeneticVariation disease BEFREE A polymorphism of angiotensinogen gene codon 174 and coronary artery disease in Japanese subjects. 9822117 1998
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis
0.100 GeneticVariation disease BEFREE The M235T polymorphism of the AGT gene modifies the risk of coronary artery disease associated with the presence of hypercholesterolemia. 18409009 2008
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis
0.100 GeneticVariation disease BEFREE AGT gene polymorphisms (M235T, T174M) are associated with coronary heart disease in a Chinese population. 22791700 2013
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis
0.100 GeneticVariation disease BEFREE In addition, most importantly, we found no interaction between angiotensin II type 1 receptor A1166C gene variation and angiotensin I-converting Insertion/Deletion polymorphism, either in connection with the risk of coronary artery disease or myocardial infarction. 9857918 1998
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis
0.100 GeneticVariation disease BEFREE Angiotensinogen gene polymorphism is associated with insulin resistance in nondiabetic men with or without coronary heart disease. 9665229 1998
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis
0.100 GeneticVariation disease BEFREE Interaction of gender, hypertension, and the angiotensinogen gene haplotypes on the risk of coronary artery disease in a large angiographic cohort. 18653189 2009
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis
0.100 GeneticVariation disease BEFREE The M235T single nucleotide polymorphism in the angiotensinogen gene is associated with coronary artery calcium in patients with a family history of coronary artery disease. 23137822 2013
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis
0.100 GeneticVariation disease BEFREE In 257 Dutch IDDM patients (188 with urinary albumin excretion (UAE) <30 mg/24 h), logistic regression analysis was used to study the relationships among, on the one hand, the insertion/deletion gene polymorphism of the angiotensin-converting enzyme gene (ACE-ID), the M235T gene polymorphism of the angiotensinogen gene (AGT-M235T), and the A1166C gene polymorphism of the angiotensin type 1 receptor gene (AT1-A1166C), and, on the other hand, UAE, retinopathy, hypertension, and coronary heart disease. 10862638 2000
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis
0.100 GeneticVariation disease BEFREE Quantitative assessment of the effect of angiotensinogen gene polymorphisms on the risk of coronary heart disease. 17846284 2007
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis
0.100 GeneticVariation disease BEFREE The present study strengthens the hypothesis of an association of both angiotensinogen gene polymorphisms with the extent of coronary heart disease. 10488958 1999
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis
0.100 GeneticVariation disease BEFREE The angiotensinogen M235T variant was analyzed in 871 consecutive patients with clinically suspected coronary artery disease submitted to coronary angiography study. 16045904 2005
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis
0.100 GeneticVariation disease BEFREE The relationship among angiotensinogen genes polymorphisms and hs-CRP and coronary artery disease. 30912862 2019
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis
0.100 GeneticVariation disease BEFREE Association of angiotensinogen gene T235 variant with increased risk of coronary heart disease. 7783537 1995
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis
0.100 GeneticVariation disease BEFREE Relationship of the rs1799752 polymorphism of the angiotensin-converting enzyme gene and the rs699 polymorphism of the angiotensinogen gene to the process of in-stent restenosis in a population of Polish patients with stable coronary artery disease. 27162064 2016
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis
0.100 GeneticVariation disease BEFREE Angiotensinogen gene M235T polymorphism and risk of coronary artery disease: a meta-analysis. 22842872 2012
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis
0.100 GeneticVariation disease BEFREE Angiotensinogen and angiotensin-I converting enzyme gene polymorphisms and the risk of coronary artery disease in Chinese. 9254851 1997
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis
0.100 GeneticVariation disease BEFREE Association of angiotensinogen M235T and A(-6)G gene polymorphisms with coronary heart disease with independence of essential hypertension: the PROCAGENE study. Prospective Cardiac Gene. 11345362 2001
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis
0.100 GeneticVariation disease BEFREE Additionally, lncRNAs have been associated with angiotensin II actions and with vascular diseases, including coronary heart disease and atherosclerosis. miRNAs, well studied in various vascular diseases, have also been recently shown to be differentially expressed in the biofluids of patients with vascular disease and mediate cell-cell communication. 24614861 2014
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis
0.100 GeneticVariation disease BEFREE A common variant of the angiotensinogen gene and the risk of coronary artery disease in a German population. 10683876 2000
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis
0.100 GeneticVariation disease BEFREE The significant relations observed between the AGT M235T variant, its protein product, and the cardiovascular disease phenotypes provide evidence for a possible role of elevated circulating AGT in the pathogenesis of coronary artery disease. 10097233 1999
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis
0.100 GeneticVariation disease BEFREE Lack of association between variants of the angiotensinogen gene and the risk of coronary artery disease in middle-aged Japanese men. 9313606 1997
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis
0.100 GeneticVariation disease BEFREE The angiotensinogen M235T polymorphism is positively associated with plasma angiotensinogen, hypertension, and coronary heart disease. 12040348 2002
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis
0.100 Biomarker disease BEFREE Nitric oxide (NO) has been shown to play a key role in the regulation of cardiac hypertrophy and fibrosis in response to myocardial ischemia in part by antagonizing the action of angiotensin II (Ang II). 15763077 2005