|
Lung Neoplasms
|
0.600 |
GeneticVariation
|
group |
LHGDN |
Soy consumption reduces the risk of non-small-cell lung cancers with epidermal growth factor receptor mutations among Japanese.
|
18429954 |
2008 |
|
Lung Neoplasms
|
0.600 |
GeneticVariation
|
group |
BEFREE |
MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib.
|
18093943 |
2007 |
|
Lung Neoplasms
|
0.600 |
GeneticVariation
|
group |
LHGDN |
EGFR assays in lung cancer.
|
18580100 |
2008 |
|
Lung Neoplasms
|
0.600 |
Biomarker
|
group |
LHGDN |
EGFR, TTF-1 and Mdm2 expression in stage III non-small cell lung cancer: a positive association.
|
18355939 |
2008 |
|
Lung Neoplasms
|
0.600 |
GeneticVariation
|
group |
LHGDN |
Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib.
|
15118073 |
2004 |
|
Lung Neoplasms
|
0.600 |
GeneticVariation
|
group |
BEFREE |
Author Correction: EZH2 inhibition sensitizes BRG1 and EGFR mutant lung tumours to TopoII inhibitors.
|
30250255 |
2018 |
|
Lung Neoplasms
|
0.600 |
GeneticVariation
|
group |
LHGDN |
Prospective study of the accuracy of EGFR mutational analysis by high-resolution melting analysis in small samples obtained from patients with non-small cell lung cancer.
|
18676744 |
2008 |
|
Lung Neoplasms
|
0.600 |
GeneticVariation
|
group |
BEFREE |
The present study demonstrates significant differences in TCR repertoires and the number of predicted neoantigens between EGFR-mutant and wild-type lung tumors.
|
30582659 |
2019 |
|
Lung Neoplasms
|
0.600 |
GeneticVariation
|
group |
LHGDN |
[Mutations in exon 19 of EGFR gene in non-small cell lung cancer from Chinese patients].
|
18543225 |
2008 |
|
Lung Neoplasms
|
0.600 |
GeneticVariation
|
group |
LHGDN |
The relationship between epidermal growth factor receptor mutations and clinicopathologic features in non-small cell lung cancers.
|
15709185 |
2005 |
|
Lung Neoplasms
|
0.600 |
GeneticVariation
|
group |
BEFREE |
Nevertheless, several lines of evidence indicate that the T790M mutation confers growth advantage to cancer cells, and it was shown that mice expressing tetracycline-inducible EGFR transgenes harboring the T790M mutation develop lung tumors.
|
19096299 |
2009 |
|
Lung Neoplasms
|
0.600 |
AlteredExpression
|
group |
BEFREE |
Nuclear trafficking of EGFR by Vps34 represses Arf expression to promote lung tumor cell survival.
|
26686095 |
2016 |
|
Lung Neoplasms
|
0.600 |
GeneticVariation
|
group |
LHGDN |
EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy.
|
15118125 |
2004 |
|
Lung Neoplasms
|
0.600 |
GeneticVariation
|
group |
BEFREE |
In addition, genetic analysis revealed that the primary rectal cancer contained nearly the same types of double-activating epidermal growth factor receptor mutations as were present in the lung tumor.
|
21835826 |
2011 |
|
Lung Neoplasms
|
0.600 |
Biomarker
|
group |
LHGDN |
Effects of gefitinib on serum epidermal growth factor receptor and HER2 in patients with advanced non-small cell lung cancer.
|
15447984 |
2004 |
|
Lung Neoplasms
|
0.600 |
GeneticVariation
|
group |
LHGDN |
Better survival with EGFR exon 19 than exon 21 mutations in gefitinib-treated non-small cell lung cancer patients is due to differential inhibition of downstream signals.
|
18407408 |
2008 |
|
Lung Neoplasms
|
0.600 |
GeneticVariation
|
group |
LHGDN |
Epidermal growth factor receptor double activating mutations involving both exons 19 and 21 exist in Chinese non-small cell lung cancer patients.
|
17537621 |
2007 |
|
Lung Neoplasms
|
0.600 |
AlteredExpression
|
group |
LHGDN |
Synchronous overexpression of epidermal growth factor receptor and HER2-neu protein is a predictor of poor outcome in patients with stage I non-small cell lung cancer.
|
14734462 |
2004 |
|
Lung Neoplasms
|
0.600 |
GeneticVariation
|
group |
LHGDN |
We sequenced exons 18-21 of the EGFR TK domain from genomic DNA isolated from 617 non-small-cell lung cancers (NSCLCs) and 524 normal lung tissue samples from the same patients and 36 neuroendocrine lung tumors collected from patients in Japan, Taiwan, the United States, and Australia and from 243 other epithelial cancers.
|
15741570 |
2005 |
|
Lung Neoplasms
|
0.600 |
Biomarker
|
group |
LHGDN |
Complex mutation patterns of epidermal growth factor receptor gene associated with variable responses to gefitinib treatment in patients with non-small cell lung cancer.
|
16870303 |
2006 |
|
Lung Neoplasms
|
0.600 |
GeneticVariation
|
group |
LHGDN |
Presence of epidermal growth factor receptor gene T790M mutation as a minor clone in non-small cell lung cancer.
|
16912157 |
2006 |
|
Lung Neoplasms
|
0.600 |
GeneticVariation
|
group |
LHGDN |
EGFR somatic doublets in lung cancer are frequent and generally arise from a pair of driver mutations uncommonly seen as singlet mutations: one-third of doublets occur at five pairs of amino acids.
|
18372921 |
2008 |
|
Lung Neoplasms
|
0.600 |
GeneticVariation
|
group |
LHGDN |
Exon 19 deletion mutations of epidermal growth factor receptor are associated with prolonged survival in non-small cell lung cancer patients treated with gefitinib or erlotinib.
|
16818686 |
2006 |
|
Lung Neoplasms
|
0.600 |
AlteredExpression
|
group |
BEFREE |
We previously demonstrated that wild type and mutant EGFRs repress the expression of the ARF tumor suppressor to promote the survival of lung tumor cells.
|
29959911 |
2018 |
|
Lung Neoplasms
|
0.600 |
Biomarker
|
group |
LHGDN |
EGFR regulation by microRNA in lung cancer: a rose by any other name ... is an increasingly complicated rose.
|
18508859 |
2008 |