A2M, alpha-2-macroglobulin, 2

N. diseases: 147; N. variants: 3
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0276496
Disease: Familial Alzheimer Disease (FAD)
Familial Alzheimer Disease (FAD)
0.310 GeneticVariation disease BEFREE Genotype analysis of A2M gene showed a significant positive correlation between A2M AA genotype and the AD patients (sporadic Alzheimer's disease (SAD) and FAD) (P = 0.001, RR = 1.56), proposing it as a possible risk factor for AD. 26289409 2016
CUI: C0276496
Disease: Familial Alzheimer Disease (FAD)
Familial Alzheimer Disease (FAD)
0.310 Biomarker disease CTD_human Increased risk for Alzheimer disease with the interaction of MPO and A2M polymorphisms. 15023809 2004
CUI: C0276496
Disease: Familial Alzheimer Disease (FAD)
Familial Alzheimer Disease (FAD)
0.310 Biomarker disease CTD_human Genetic association of an alpha2-macroglobulin (Val1000lle) polymorphism and Alzheimer's disease. 9811940 1998
CUI: C0276496
Disease: Familial Alzheimer Disease (FAD)
Familial Alzheimer Disease (FAD)
0.310 Biomarker disease CTD_human Alpha-2 macroglobulin is genetically associated with Alzheimer disease. 9697696 1998