Breast Carcinoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
Quantification of C-ERB-B2 gene amplification in breast cancer cells using fluorescence in situ hybridization and digital image analysis.
|
8616779 |
1996 |
Breast Carcinoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Expression of estrogen receptor beta messenger RNA variant in breast cancer.
|
9443393 |
1998 |
Breast Carcinoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Increased expression of estrogen receptor beta mRNA in tamoxifen-resistant breast cancer patients.
|
10554009 |
1999 |
Breast Carcinoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
To complement the RNA expression studies, we have developed ER-beta-specific antibodies to characterize ER-beta protein expression in breast cancer cell lines and tumors.
|
10554010 |
1999 |
Breast Carcinoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
We determined that ER-beta is expressed in normal and tumor human breast tissue as well as in breast cancer cell lines.
|
10601611 |
2000 |
Breast Carcinoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Expression levels of estrogen receptor-alpha, estrogen receptor-beta, coactivators, and corepressors in breast cancer.
|
10690532 |
2000 |
Breast Carcinoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
Prognostic significance of oestrogen receptor beta in breast cancer.
|
10759732 |
2000 |
Breast Carcinoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Detection of estrogen receptor-beta mRNA in breast cancer using RT-PCR.
|
10763153 |
2000 |
Breast Carcinoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
Estrogen receptor beta in the breast: role in estrogen responsiveness and development of breast cancer.
|
11162931 |
2000 |
Breast Carcinoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Clinical value of the wild-type estrogen receptor beta expression in breast cancer.
|
11165756 |
2001 |
Breast Carcinoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
We addressed the clinicopathological significance of the oestrogen receptor (ER) beta protein, including an ERbeta variant, ERbetacx, in normal human breast and breast cancer.
|
11818203 |
2002 |
Breast Carcinoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
However, our data provide preliminary evidence that the expression of oestrogen receptor beta protein isoforms may differ in primary tumours of breast cancer patients who prove to have differential sensitivity to tamoxifen therapy.
|
12454770 |
2002 |
Breast Carcinoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
In this first association study about breast cancer risk and polymorphisms in the ERbeta gene we have screened 219 Finnish sporadic breast cancer cases and 248 ethnically matched male controls.
|
12846425 |
2003 |
Breast Carcinoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Collectively, ERbeta mRNA decreases in the process of BC development, but seems to be associated with poor differentiation.
|
12889601 |
2003 |
Breast Carcinoma
|
0.400 |
PosttranslationalModification
|
disease |
BEFREE |
Real-time polymerase chain reaction (PCR) was used to investigate the methylation status of the ER beta gene in the ER beta negative breast cancer cell lines SkBr3 and MDA-MB-435.
|
14517838 |
2003 |
Breast Carcinoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Treatment of breast cancer cells with demethylating agent effectively reactivated the expression of ERbeta mRNA.
|
14576822 |
2003 |
Breast Carcinoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Our results are consistent with the hypothesis of a joint effect of estrogen receptor beta sequence variants and endogenous estrogen exposure on breast cancer risk.
|
14633679 |
2003 |
Breast Carcinoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
Estrogen receptor beta inhibits human breast cancer cell proliferation and tumor formation by causing a G2 cell cycle arrest.
|
14729654 |
2004 |
Breast Carcinoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
DNA methylation inhibitor, procainamide, may decrease the tamoxifen resistance by inducing overexpression of the estrogen receptor beta in breast cancer patients.
|
15325017 |
2004 |
Breast Carcinoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
This altered expression pattern of ERbeta isoforms in breast cancer should be taken into account in future ERbeta-based clinical applications.
|
15374639 |
2004 |
Breast Carcinoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
This study has confirmed the hypothesis that expression of ERalpha is an important determinant of breast cancer progression, and has further demonstrated that ERbeta1 may play a role in the response of breast cancers to endocrine therapy.
|
15477865 |
2004 |
Breast Carcinoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
Estrogen receptor beta and breast cancer.
|
15522549 |
2004 |
Breast Carcinoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Correlation of mRNA for oestrogen receptor beta splice variants ERbeta1, ERbeta2/ERbetacx and ERbeta5 with outcome in endocrine-treated breast cancer.
|
15591034 |
2004 |
Breast Carcinoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
We define several other haplotypes in Ashkenazi Jews in both ESR1 and ESR2 that may elevate susceptibility to breast cancer.
|
15604249 |
2004 |
Breast Carcinoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
Prospective evaluation of estrogen receptor-beta in predicting response to neoadjuvant antiestrogen therapy in elderly breast cancer patients.
|
15613450 |
2004 |