ALB, albumin, 213

N. diseases: 1198; N. variants: 21
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.400 Biomarker disease BEFREE Of 256 participants (mean ± SD glomerular filtration rate [iothalamate] = 148 ± 45 mL/min, and median [interquartile range] urine albumin/creatinine = 39 [14-221] mg/g), 76 developed ESRD and 125 died during a median follow-up period of 15.2 and 15.7 years, respectively. 28934744 2017
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.400 AlteredExpression disease BEFREE A significant negative correlation was observed between albumin levels and fat mass in both healthy subjects and inflamed ESRD patients. 22675238 2012
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.400 Biomarker disease BEFREE Participants from the Epidemiology of Diabetes Complications Study with DNA available were studied for the incidence of microalbuminuria (albumin excretion rate [AER] 20-200 microg/min), macroalbuminuria (AER >200 microg/min), ESRD (renal dialysis or transplantation), and renal function decline (a decline > or =30 ml/min per 1.73 m(2) from baseline estimated [by the Cockcroft-Gault equation] glomerular filtration rate [eGFR] in those with baseline eGFR >60 ml/min per 1.73 m(2)). 19720796 2009
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.400 Biomarker disease BEFREE An increase in the ratio of oxidized to unoxidized albumin was determined using 5/6 nephrectomized rats (CRF rats) compared to a control group. 17387602 2007
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.400 Biomarker disease BEFREE Diabetic nephropathy was defined as macroalbuminuria (urinary albumin excretion rate >200 microg/min or >300 mg/24 h) or end-stage renal disease. 17337502 2007
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.400 Biomarker disease BEFREE Elevated urinary albumin excretion and decreased glomerular filtration rate (GFR) are risk factors for cardiovascular death and end-stage renal disease in individuals with type 2 diabetes mellitus (DM). 15112169 2004
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.400 Biomarker disease BEFREE When comparing patients with a mutant allele with the wild genotype there was no difference between the patients with end-stage renal disease, proteinuria, microalbuminuria, and those with a normal albumin excretion rate (df =3, chi2 =1.62, 1.31 and 0.77). 12631336 2003
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.400 Biomarker disease BEFREE Genomic DNA was obtained from 659 patients: 307 with normal urinary albumin excretion despite diabetes duration of >15 years (control subjects) and 352 with advanced diabetic nephropathy, of whom 200 had persistent proteinuria and 152 had end-stage renal disease (ESRD). 11916943 2002
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.400 Biomarker disease BEFREE In a two-by-two factorial study of urinary albumin in non-diabetic Polynesians, 90 people with a first degree relative (FDR) with end-stage renal failure (ESRF) and diabetes (group 1) were compared with 90 people with a FDR with non-diabetic ESRF (group 2), with 90 people with a FDR with diabetes but no known nephropathy (group 3) and 90 people with no known relatives with either diabetes or nephropathy (group 4). 11168340 2001
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.400 Biomarker disease CTD_human [Experimental study on treatment of chronic renal failure with yishen qudu capsule]. 11938814 2000
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.400 Biomarker disease BEFREE There is no evidence that shifts of albumin to the extravascular space or that dilution of the plasma by volume expansion plays any role in causing hypoalbuminemia in ESRD patients. 9848794 1998
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.400 Biomarker disease BEFREE There were significant inverse correlations between serum albumin and Lp(a) (r = -0.33, p < 0.01), total cholesterol (r = -0.31, p < 0.01), LDL (r = -0.39, p < 0.01) or ApoB (r = -0.35, p < 0.01) in ESRD patients. 9237283 1997