|
Myocardial Infarction
|
0.400 |
Biomarker
|
disease |
BEFREE |
Genetic abnormalities specific to factor V, prothrombin,and homocysteine metabolism increase the risk for myocardial infarction and ischemic stroke, particularly among younger patients and women.
|
14660985 |
2003 |
|
Myocardial Infarction
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Genotyping at the 20210 prothrombin gene locus was performed in 162 patients with a first episode of myocardial infarction (MI) or unstable angina (UA) occurring before 65 years of age.
|
15377476 |
2004 |
|
Myocardial Infarction
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
We studied 609 patients with venous thromboembolism (287 with factor V Leiden, and 322 with prothrombin 20210A), 174 patients with myocardial infarction (78 with factor V Leiden, and 96 with prothrombin 20210A), and 198 controls (96 with factor V Leiden, and 102 with prothrombin 20210A).
|
18387978 |
2008 |
|
Myocardial Infarction
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
In this study, we proposed to determine the prevalence of 20210A prothrombin variant among Tunisian population, and to evaluate the potential relevance of this variant with myocardial infarction.
|
27306359 |
2016 |
|
Myocardial Infarction
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
We report a case of myocardial infarction at a young age in a subject heterozygous for the G20210A prothrombin gene variant and homozygous for the C677T MTHFR polymorphism, who presented a strong family history of atherothrombosis.
|
17920139 |
2008 |
|
Myocardial Infarction
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
In conclusion, our data indicate that the G20210A mutation in the prothrombin gene was the only genetic prothrombotic risk factor associated with the risk of developing MI under the age of 36 years.
|
12888875 |
2003 |
|
Myocardial Infarction
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
G20210A prothrombin gene polymorphism may represent a modest but significant risk factor for myocardial infarction at young ages and favour the expression of ischaemic heart disease among individuals who have a limited extent of coronary atherosclerosis at angiography.
|
14676252 |
2004 |
|
Myocardial Infarction
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
When a coagulation defect was present (ie, the 20210 AG prothrombin genotype or the factor V Leiden mutation), the risk of myocardial infarction for carriers versus noncarriers was 1.4 (95% CI, 0.9 to 2.2).
|
9531249 |
1998 |
|
Myocardial Infarction
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
A common prothrombin variant (20210 G to A) increases the risk of myocardial infarction in young women.
|
9292507 |
1997 |
|
Myocardial Infarction
|
0.400 |
Biomarker
|
disease |
CTD_human |
When a coagulation defect was present (ie, the 20210 AG prothrombin genotype or the factor V Leiden mutation), the risk of myocardial infarction for carriers versus noncarriers was 1.4 (95% CI, 0.9 to 2.2).
|
9531249 |
1998 |
|
Myocardial Infarction
|
0.400 |
Biomarker
|
disease |
CTD_human |
A common prothrombin variant (20210 G to A) increases the risk of myocardial infarction in young women.
|
9292507 |
1997 |
|
Myocardial Infarction
|
0.400 |
Biomarker
|
disease |
CTD_human |
Our findings suggest that the 20210 G-->A mutation in the prothrombin gene is a genetic risk factor for MI.
|
10027711 |
1999 |
|
Myocardial Infarction
|
0.400 |
Biomarker
|
disease |
LHGDN |
Acute myocardial infarction following an arthropod bite: is hereditary thrombophilia a contributing factor?
|
16988555 |
2006 |
|
Myocardial Infarction
|
0.400 |
GeneticVariation
|
disease |
LHGDN |
A patient with hemophilia A is reported who had an acute myocardial infarction and in whom investigation for hereditary thrombophilia showed a prothrombotic molecular defect, the G20210A prothrombin mutation.
|
16015425 |
2005 |
|
Myocardial Infarction
|
0.400 |
GeneticVariation
|
disease |
LHGDN |
[Frequency of prothrombin gene G20210A variant in the 3'-untranslated region in Zhuang ethnic Chinese].
|
15952132 |
2005 |