Intelligence
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.
|
29326435 |
2019 |
Multiple Sclerosis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Although additional work is needed to scrutinise the genetic effect of the SORCS3-covering haplotype, this study suggests that SORCS3 may also be important in MS pathogenesis.
|
26362888 |
2016 |
Attention deficit hyperactivity disorder
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder.
|
30478444 |
2019 |
Alzheimer's Disease
|
0.110 |
GeneticVariation
|
disease |
GWASCAT |
Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
|
26830138 |
2016 |
mathematical ability
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.
|
30038396 |
2018 |
Diastolic blood pressure
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.
|
30224653 |
2018 |
Mental disorders
|
0.020 |
Biomarker
|
group |
BEFREE |
Genetic and functional studies have linked SorCS receptors to psychiatric disorders, Alzheimer's disease and type 2 diabetes, demonstrating critical roles in neuronal functionality and metabolic control.
|
28827148 |
2017 |
Abnormal behavior
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
Genetic and functional studies have linked SorCS receptors to psychiatric disorders, Alzheimer's disease and type 2 diabetes, demonstrating critical roles in neuronal functionality and metabolic control.
|
28827148 |
2017 |
Major Depressive Disorder
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression.
|
29700475 |
2018 |
Intelligence
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.
|
29942086 |
2018 |
Major Depressive Disorder
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways.
|
29662059 |
2018 |
Major Depressive Disorder
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions.
|
30718901 |
2019 |
Major Depressive Disorder
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Identification of 15 genetic loci associated with risk of major depression in individuals of European descent.
|
27479909 |
2016 |
Child Development Disorders, Pervasive
|
0.100 |
GeneticVariation
|
group |
GWASCAT |
Identification of common genetic risk variants for autism spectrum disorder.
|
30804558 |
2019 |
Major Depressive Disorder
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Identification of common genetic risk variants for autism spectrum disorder.
|
30804558 |
2019 |
Intelligence
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets.
|
29186694 |
2017 |
Cardiovascular Diseases
|
0.100 |
GeneticVariation
|
group |
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
Systolic Pressure
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
Mood Disorders
|
0.100 |
GeneticVariation
|
group |
GWASCAT |
Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.
|
29942085 |
2018 |
Major Depressive Disorder
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.
|
29942085 |
2018 |
Mental Depression
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Notably, the SORCS3 gene is genome-wide significantly associated with depression and serum protein levels of sortilin are reduced in depressed individuals.
|
29499509 |
2018 |
Depressive disorder
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Notably, the SORCS3 gene is genome-wide significantly associated with depression and serum protein levels of sortilin are reduced in depressed individuals.
|
29499509 |
2018 |
Depressed mood
|
0.010 |
GeneticVariation
|
phenotype |
BEFREE |
Notably, the SORCS3 gene is genome-wide significantly associated with depression and serum protein levels of sortilin are reduced in depressed individuals.
|
29499509 |
2018 |
Intelligence
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways.
|
31374203 |
2019 |
Schizophrenia
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways.
|
31374203 |
2019 |