|
Uterine Fibroids
|
0.130 |
Biomarker
|
group |
BEFREE |
BET1L and TNRC6B associate with uterine fibroid risk among European Americans.
|
23604678 |
2013 |
|
Uterine Fibroids
|
0.130 |
GeneticVariation
|
group |
BEFREE |
Two SNPs, rs2280543 from BET1L (χ<sup>2</sup> = 18.3, OR = 0.64, P = 1.87 × 10<sup>-5</sup>) and rs12484776 from TNRC6B (χ<sup>2</sup> = 19.7, OR = 1.40, P = 8.91 × 10<sup>-6</sup>), were identified as significantly associated with the disease status of UL.
|
29743541 |
2018 |
|
Uterine Fibroids
|
0.130 |
GeneticVariation
|
group |
BEFREE |
Replication of GWAS loci revealed the moderate effect of TNRC6B locus on susceptibility of Saudi women to develop uterine leiomyomas.
|
27987337 |
2017 |
|
Malignant neoplasm of prostate
|
0.110 |
Biomarker
|
disease |
BEFREE |
Using a series of experiments in human prostate cancer cell lines, we validate the highest ranking prediction (TNRC6B) as a ceRNA of PTEN.
|
28798471 |
2017 |
|
Prostate carcinoma
|
0.110 |
Biomarker
|
disease |
BEFREE |
Using a series of experiments in human prostate cancer cell lines, we validate the highest ranking prediction (TNRC6B) as a ceRNA of PTEN.
|
28798471 |
2017 |
|
Squamous cell carcinoma of esophagus
|
0.020 |
GeneticVariation
|
disease |
BEFREE |
Six miR-SNPs in miRNA processing machinery genes, including Dicer (rs3742330), RAN (rs14035), XPO5 (rs11077), TNRC6B (rs9623117), GEMIN3 (rs197412), and GEMIN4 (rs2740348), were evaluated for their association with esophageal squamous cell carcinoma (ESCC).
|
29226993 |
2018 |
|
Squamous cell carcinoma of esophagus
|
0.020 |
GeneticVariation
|
disease |
BEFREE |
Our results suggest that the trinucleotide repeat containing 6B mutation may be a candidate predisposing gene in esophageal squamous cell carcinoma.
|
28459198 |
2017 |
|
Fibroid Tumor
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Variants in BET1L and TNRC6B associate with increasing fibroid volume and fibroid type among European Americans.
|
23892540 |
2013 |
|
Chronic Lymphocytic Leukemia
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).
|
25793711 |
2015 |
|
Respiratory Failure
|
0.010 |
Biomarker
|
disease |
BEFREE |
However, the majority of TNRC6b and all TNRC6c mutants die within 24h after birth, the latter with respiratory failure.
|
28811219 |
2017 |
|
Autism Spectrum Disorders
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
We did not identify a significant association of TNRC6B mutations with ASD.
|
25228304 |
2014 |
|
Polycystic Ovary Syndrome
|
0.300 |
Biomarker
|
disease |
CTD_human |
Progesterone resistance in PCOS endometrium: a microarray analysis in clomiphene citrate-treated and artificial menstrual cycles.
|
21411543 |
2011 |
|
Sclerocystic Ovaries
|
0.300 |
Biomarker
|
disease |
CTD_human |
Progesterone resistance in PCOS endometrium: a microarray analysis in clomiphene citrate-treated and artificial menstrual cycles.
|
21411543 |
2011 |
|
Neurodevelopmental Disorders
|
0.300 |
Biomarker
|
group |
CTD_human |
Targeted sequencing identifies 91 neurodevelopmental-disorder risk genes with autism and developmental-disability biases.
|
28191889 |
2017 |
|
Uterine Fibroids
|
0.130 |
GeneticVariation
|
group |
GWASCAT |
A Trans-Ethnic Genome-Wide Association Study of Uterine Fibroids.
|
31249589 |
2019 |
|
Uterine Fibroids
|
0.130 |
GeneticVariation
|
group |
GWASCAT |
A genome-wide association study identifies three loci associated with susceptibility to uterine fibroids.
|
21460842 |
2011 |
|
Uterine Fibroids
|
0.130 |
GeneticVariation
|
group |
GWASCAT |
Genome-wide association and epidemiological analyses reveal common genetic origins between uterine leiomyomata and endometriosis.
|
31649266 |
2019 |
|
Uterine Fibroids
|
0.130 |
GeneticVariation
|
group |
GWASCAT |
Variants associating with uterine leiomyoma highlight genetic background shared by various cancers and hormone-related traits.
|
30194396 |
2018 |
|
Prostate carcinoma
|
0.110 |
GeneticVariation
|
disease |
GWASCAT |
Sequence variants at 22q13 are associated with prostate cancer risk.
|
19117981 |
2009 |
|
Prostate carcinoma
|
0.110 |
GeneticVariation
|
disease |
GWASCAT |
Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci.
|
29892016 |
2018 |
|
Body Height
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
A genome-wide association study of northwestern Europeans involves the C-type natriuretic peptide signaling pathway in the etiology of human height variation.
|
19570815 |
2009 |
|
Circadian Rhythms
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genome-Wide Association Analyses in 128,266 Individuals Identifies New Morningness and Sleep Duration Loci.
|
27494321 |
2016 |
|
Circadian Rhythms
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genome-wide association analysis of insomnia complaints identifies risk genes and genetic overlap with psychiatric and metabolic traits.
|
28604731 |
2017 |
|
Circadian Rhythms
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genome-wide association analysis identifies novel loci for chronotype in 100,420 individuals from the UK Biobank.
|
26955885 |
2016 |
|
Red Blood Cell Count measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |