FJX1, four-jointed box kinase 1, 24147

N. diseases: 27; N. variants: 0
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2020284
Disease: Stickler syndrome, type 1
Stickler syndrome, type 1 		0.010 Biomarker disease BEFREE Furthermore, FJX1 null mice develop significantly fewer colonic polyps than wild-type littermates after combined dextran sodium sulfate (DSS) and azoxymethane (AOM) treatment. 23922772 2013
CUI: C2827407
Disease: Infectious Otitis Media
Infectious Otitis Media 		0.010 Biomarker disease BEFREE Furthermore, FJX1 null mice develop significantly fewer colonic polyps than wild-type littermates after combined dextran sodium sulfate (DSS) and azoxymethane (AOM) treatment. 23922772 2013
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.010 AlteredExpression disease BEFREE FJX1 mRNA expression in colorectal cancer tissues is significantly correlated with changes in known angiogenesis genes. 23922772 2013
CUI: C3149841
Disease: POLYCYSTIC KIDNEY DISEASE 1
POLYCYSTIC KIDNEY DISEASE 1 		0.010 AlteredExpression disease BEFREE Indeed, we show here that in Pkd1 conditional deletion mice expression of the PCP component Four-jointed (Fjx1) is decreased while its expression is required during tissue regeneration. 19401297 2009