Hodgkin Disease
|
0.090 |
Biomarker
|
disease |
BEFREE |
Hodgkin's lymphoma (HL) has a unique immunophenotype derived from immunohistochemistry (positive for CD15, CD30, and Pax-5; negative for CD3, CD20 in most cases, and CD45).
|
30350336 |
2019 |
Hodgkin Disease
|
0.090 |
Biomarker
|
disease |
BEFREE |
A lymph node biopsy showed the histological features of HD (mixed cellularity) with infiltrating CD8+ lymphocytes, and immunohistochemical examination revealed the following phenotype of Reed-Sternberg cells: LeuM1/CD15+, BerH2/CD30+, L26/PanB-, UCHL-1/CD45RO-, cyCD3-, CD4, CD8-, CD20-, CD79a-, EMA-, EBER-1+, LMP-1+.
|
11372737 |
2001 |
Hodgkin Disease
|
0.090 |
Biomarker
|
disease |
BEFREE |
Following a wedge resection, histopathological examination showed Reed-Sternberg cells that were positive for CD-15 and CD-30, which is typical of HL.
|
29742695 |
2018 |
Hodgkin Disease
|
0.090 |
Biomarker
|
disease |
BEFREE |
In addition to ALK protein, all tumors expressed epithelial membrane antigen and lacked CD15, features that may be of value in differentiating ALCL from Hodgkin's disease.
|
9490693 |
1998 |
Hodgkin Disease
|
0.090 |
Biomarker
|
disease |
BEFREE |
No CD30/CD15 double-positive cells could be enriched from a lymph node affected by the lymphocyte predominant subtype of HD, activated lymph nodes or peripheral blood of healthy donors.
|
9707610 |
1998 |
Hodgkin Disease
|
0.090 |
Biomarker
|
disease |
BEFREE |
Paraffin-embedded tissue sections from the original diagnostic HD and the monomorphic growths were stained for Leu-M1 (CD15), leukocyte common antigen (LCA, CD45), pan B-cell markers LN1, LN2, and L26, and pan T-cell marker UCHL1 (CD45R) reactive in paraffin-embedded tissues.
|
2297052 |
1990 |
Hodgkin Disease
|
0.090 |
AlteredExpression
|
disease |
BEFREE |
The cells expressed the HD-associated surface antigens CD30 and CD15 as well as the transferrin receptor (CD71).
|
8605360 |
1996 |
Hodgkin Disease
|
0.090 |
Biomarker
|
disease |
BEFREE |
The recently identified lymphocyte-rich classical (lrc) HL is characterized by HRS cells with the immunophenotype of classical HRS cells (CD30(+)CD15(+)CD20(-)CD45(-)) but an infiltrate similar to lpHL and a clinical behavior resembling lpHL.
|
12670918 |
2003 |
Hodgkin Disease
|
0.090 |
AlteredExpression
|
disease |
BEFREE |
Three of the cases expressing CD15 showed subsequent evidence of disseminated Hodgkin's disease.
|
1384376 |
1992 |