CXCL3, C-X-C motif chemokine ligand 3, 2921

N. diseases: 47; N. variants: 0
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast
0.310 Biomarker disease BEFREE Our results support a functional role of CXCL3 in breast cancer metastasis and as a viable target for cancer therapy. 24605943 2014
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast
0.310 Biomarker disease CTD_human ERE-independent ERalpha target genes differentially expressed in human breast tumors. 16298037 2005
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.310 Biomarker disease CTD_human ERE-independent ERalpha target genes differentially expressed in human breast tumors. 16298037 2005
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.310 Biomarker disease BEFREE Our results support a functional role of CXCL3 in breast cancer metastasis and as a viable target for cancer therapy. 24605943 2014
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.310 Biomarker group CTD_human ERE-independent ERalpha target genes differentially expressed in human breast tumors. 16298037 2005
CUI: C0037274
Disease: Dermatologic disorders
Dermatologic disorders
0.300 Biomarker group CTD_human Gene expression profiles in peripheral lymphocytes by arsenic exposure and skin lesion status in a Bangladeshi population. 16835338 2006
CUI: C0274861
Disease: Arsenic Poisoning, Inorganic
Arsenic Poisoning, Inorganic
0.300 Biomarker disease CTD_human Gene expression profiles in peripheral lymphocytes by arsenic exposure and skin lesion status in a Bangladeshi population. 16835338 2006
Nervous System, Organic Arsenic Poisoning
0.300 Biomarker disease CTD_human Gene expression profiles in peripheral lymphocytes by arsenic exposure and skin lesion status in a Bangladeshi population. 16835338 2006
CUI: C0311375
Disease: Arsenic Poisoning
Arsenic Poisoning
0.300 Biomarker disease CTD_human Gene expression profiles in peripheral lymphocytes by arsenic exposure and skin lesion status in a Bangladeshi population. 16835338 2006
CUI: C0751851
Disease: Arsenic Encephalopathy
Arsenic Encephalopathy
0.300 Biomarker disease CTD_human Gene expression profiles in peripheral lymphocytes by arsenic exposure and skin lesion status in a Bangladeshi population. 16835338 2006
CUI: C0751852
Disease: Arsenic Induced Polyneuropathy
Arsenic Induced Polyneuropathy
0.300 Biomarker disease CTD_human Gene expression profiles in peripheral lymphocytes by arsenic exposure and skin lesion status in a Bangladeshi population. 16835338 2006
CUI: C1135196
Disease: Heart Failure, Diastolic
Heart Failure, Diastolic
0.300 Biomarker disease CTD_human In Silico Analysis of Differential Gene Expression in Three Common Rat Models of Diastolic Dysfunction. 29556499 2018
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human
0.300 Biomarker disease CTD_human ERE-independent ERalpha target genes differentially expressed in human breast tumors. 16298037 2005
CUI: C4704874
Disease: Mammary Carcinoma, Human
Mammary Carcinoma, Human
0.300 Biomarker disease CTD_human ERE-independent ERalpha target genes differentially expressed in human breast tumors. 16298037 2005
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.060 Biomarker group BEFREE We showed by microarray and by RT-PCR that NDRG3 overexpression up-regulates the expression of many angiogenic chemokines including CXCL1 (chemokine ligand 1), CXCL3 (chemokine ligand 3) and CXCL5 (chemokine ligand 5), which may increase angiogenesis of tumors. 18975380 2009
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.060 Biomarker group BEFREE Molecular and functional characterization of tumor-induced factor (TIF): Hamster homolog of CXCL3 (GRO<sub>γ</sub>) displays tumor suppressive activity. 29276973 2018
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.060 Biomarker group BEFREE CCK-8, transwell assays and growth of tumor xenografts were conducted to characterize the effects of CXCL3 on PC-3 cells' proliferation and migration. 29524043 2018
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.050 Biomarker group BEFREE CXCL3 was reportedly associated with the invasion and metastasis of various malignancies, the role of CXCL3, however, in preeclampsia has not been fully discussed. 29884302 2018
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.050 Biomarker group BEFREE CXCL3 belongs to the CXC-type chemokine family and is known to play a multifaceted role in various human malignancies. 31667838 2020
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.050 Biomarker group BEFREE CXCL3 and its receptor CXCR2 were considered to play particularly important roles in the progression of malignancies. 26837773 2016
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.050 Biomarker group BEFREE Our results support a functional role of CXCL3 in breast cancer metastasis and as a viable target for cancer therapy. 24605943 2014
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.040 Biomarker phenotype BEFREE Furthermore, GRO-3 was related to metastasis formation, and IL-8 was associated with survival, suggesting a potential predictive power of these markers. 20162422 2010
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.040 Biomarker phenotype BEFREE Our results support a functional role of CXCL3 in breast cancer metastasis and as a viable target for cancer therapy. 24605943 2014
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.040 Biomarker phenotype BEFREE CXCL3 was reportedly associated with the invasion and metastasis of various malignancies, the role of CXCL3, however, in preeclampsia has not been fully discussed. 29884302 2018
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.020 Biomarker disease BEFREE The KRAS<sup>∗</sup>-IRF2-CXCL3-CXCR2 axis provides a framework for patient selection and combination therapies to enhance the effectiveness of ICB therapy in CRC. 30905761 2019