|
Amyloidosis
|
0.400 |
Biomarker
|
disease |
BEFREE |
<b>Methods:</b> Paraffin-embedded tissue sections from 25 autopsied individuals (age at death 44.4-88.6 years) with AGel amyloidosis were stained with HE, Congo red and Herovici stains and immunohistochemistry against the low molecular weight gelsolin fraction was performed.
|
31122115 |
2019 |
|
Amyloidosis
|
0.400 |
Biomarker
|
disease |
BEFREE |
1-Palmitoyl-2-(9'-oxononanoyl)-sn-glycero-3-phosphocholine, an oxidized phospholipid, accelerates Finnish type familial gelsolin amyloidosis in vitro.
|
21545139 |
2011 |
|
Amyloidosis
|
0.400 |
Biomarker
|
disease |
BEFREE |
Gelsolin amyloidosis typically involves the nerves and skin, with only rare reported involvement of the kidney.
|
22938848 |
2013 |
|
Amyloidosis
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
A new heterozygous G duplicate in exon1 (c.100dupG) of gelsolin gene causes Finnish gelsolin amyloidosis in a Chinese family.
|
30417985 |
2018 |
|
Amyloidosis
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Altered platelet shape change in hereditary gelsolin Asp187Asn-related amyloidosis.
|
10744159 |
2000 |
|
Amyloidosis
|
0.400 |
GeneticVariation
|
disease |
LHGDN |
Ardalan-Shoja-Kiuru syndrome--hereditary gelsolin amyloidosis plus retinitis pigmentosa.
|
17720986 |
2008 |
|
Amyloidosis
|
0.400 |
Biomarker
|
disease |
BEFREE |
By extension, the biochemical results herein suggest that tissue-selective deposition characteristic of the gelsolin amyloidoses is likely influenced by the extracellular localization of distinct glycosaminoglycans.
|
16475811 |
2006 |
|
Amyloidosis
|
0.400 |
Biomarker
|
disease |
BEFREE |
Ca2+ binding protects against gelsolin amyloidosis.
|
15336957 |
2004 |
|
Amyloidosis
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Cardiac conduction alterations in a French family with amyloidosis of the Finnish type with the p.Asp187Tyr mutation in the GSN gene.
|
16258946 |
2006 |
|
Amyloidosis
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Causes of death and life span in Finnish gelsolin amyloidosis.
|
27137880 |
2016 |
|
Amyloidosis
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Common origin of the gelsolin gene variant in 62 Finnish AGel amyloidosis families.
|
29167514 |
2018 |
|
Amyloidosis
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Cutis laxa in hereditary gelsolin amyloidosis.
|
15727635 |
2005 |
|
Amyloidosis
|
0.400 |
Biomarker
|
disease |
BEFREE |
During 1986 through 2004, 35 gelsolin amyloidosis patients underwent surgery, totaling 67 operations and 95 procedures; 89 percent consulted a plastic surgeon for brow ptosis or blepharochalasis, 15 percent for problems in oral function, and 21 percent for ocular dryness or corneal ulcers.
|
21617468 |
2011 |
|
Amyloidosis
|
0.400 |
Biomarker
|
disease |
BEFREE |
Familial amyloidotic polyneuropathy type IV--gelsolin amyloidosis.
|
22512621 |
2012 |
|
Amyloidosis
|
0.400 |
Biomarker
|
disease |
BEFREE |
Fifty patients with AGel amyloidosis were enrolled in the study.
|
30848402 |
2019 |
|
Amyloidosis
|
0.400 |
Biomarker
|
disease |
GENOMICS_ENGLAND |
Finnish hereditary amyloidosis is caused by a single nucleotide substitution in the gelsolin gene.
|
2176164 |
1990 |
|
Amyloidosis
|
0.400 |
Biomarker
|
disease |
BEFREE |
Follow-up of these cases might give us more insight into pathogenicity and potential treatment strategy of this atypical presentation of gelsolin amyloidosis.
|
24601799 |
2014 |
|
Amyloidosis
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Gender differences in the clinical course of Finnish gelsolin amyloidosis.
|
26805765 |
2016 |
|
Amyloidosis
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Heavy-chain amyloidosis in TGFBI-negative and gelsolin-negative atypical lattice corneal dystrophy.
|
21743312 |
2011 |
|
Amyloidosis
|
0.400 |
Biomarker
|
disease |
BEFREE |
Here we report the clinical, kidney biopsy, and mass spectrometry findings in 12 cases of renal gelsolin amyloidosis.
|
28139293 |
2017 |
|
Amyloidosis
|
0.400 |
Biomarker
|
disease |
BEFREE |
Hereditary gelsolin amyloidosis mimicking Sjögren's syndrome.
|
19701715 |
2009 |
|
Amyloidosis
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Herein, we review what is known about the genetics, biochemistry and pathology of familial amyloidosis of Finnish type (FAF) or gelsolin amyloidosis.
|
22360545 |
2012 |
|
Amyloidosis
|
0.400 |
Biomarker
|
disease |
BEFREE |
Histological, immunohistochemical, and electron microscopic studies showed consistent deposition of gelsolin amyloid (AGel), particularly in the vascular walls and perineurial sheaths.
|
12071640 |
2002 |
|
Amyloidosis
|
0.400 |
Biomarker
|
disease |
BEFREE |
Immunoblotting with anti-gelsolin and amyloid-specific antibodies and sequence analyses were used to study the fragmentation pattern of gelsolin.
|
14640038 |
2003 |
|
Amyloidosis
|
0.400 |
Biomarker
|
disease |
BEFREE |
Immunohistochemical localization of amyloid in Finnish hereditary amyloidosis with antibodies to gelsolin peptides.
|
1848334 |
1991 |