HFE, homeostatic iron regulator, 3077

N. diseases: 415; N. variants: 59
Disease: Hepatitis C, Chronic ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0524910
Disease: Hepatitis C, Chronic
Hepatitis C, Chronic 		0.100 GeneticVariation disease BEFREE Hemochromatosis gene mutations in chronic hepatitis C patients with and without liver siderosis. 10568758 2000
CUI: C0524910
Disease: Hepatitis C, Chronic
Hepatitis C, Chronic 		0.100 GeneticVariation disease BEFREE The relation of iron status and hemochromatosis gene mutations in patients with chronic hepatitis C. 9869610 1999
CUI: C0524910
Disease: Hepatitis C, Chronic
Hepatitis C, Chronic 		0.100 GeneticVariation disease BEFREE We evaluated whether the recently described C282Y mutation of the hemochromatosis gene, designated HFE (responsible for at least 83% of hereditary hemochromatosis), was associated with more advanced liver disease in chronic hepatitis C. One hundred thirty-seven patients with biopsy-proven chronic hepatitis C were studied and liver biopsies scored for necroinflammation (grade 0-18) and fibrosis (stage 0-6). 9620344 1998