|
Mammary Neoplasms
|
0.400 |
GeneticVariation
|
group |
LHGDN |
Distinct expression of Survivin splice variants in breast carcinomas.
|
16142334 |
2005 |
|
Mammary Neoplasms
|
0.400 |
GeneticVariation
|
group |
LHGDN |
Do the survivin (BIRC5) splice variants modulate or add to the prognostic value of total survivin in breast cancer?
|
16873289 |
2006 |
|
Colorectal Carcinoma
|
0.390 |
GeneticVariation
|
disease |
BEFREE |
Synergistic Effect of Simvastatin Plus Radiation in Gastric Cancer and Colorectal Cancer: Implications of BIRC5 and Connective Tissue Growth Factor.
|
26277021 |
2015 |
|
Colorectal Carcinoma
|
0.390 |
GeneticVariation
|
disease |
BEFREE |
Infection with pAd-T34A caused spontaneous apoptosis in cell lines of breast, cervical, prostate, lung, and colorectal cancer.
|
11581299 |
2001 |
|
Lung Neoplasms
|
0.390 |
GeneticVariation
|
group |
LHGDN |
Polymorphisms in the survivin gene and the risk of lung cancer.
|
17961802 |
2008 |
|
Breast Carcinoma
|
0.370 |
GeneticVariation
|
disease |
BEFREE |
Do the survivin (BIRC5) splice variants modulate or add to the prognostic value of total survivin in breast cancer?
|
16873289 |
2006 |
|
Malignant neoplasm of breast
|
0.360 |
GeneticVariation
|
disease |
BEFREE |
Do the survivin (BIRC5) splice variants modulate or add to the prognostic value of total survivin in breast cancer?
|
16873289 |
2006 |
|
Non-Small Cell Lung Carcinoma
|
0.350 |
GeneticVariation
|
disease |
BEFREE |
Survival analyses of 19 DEMs in the DEM‑DEG regulatory network and 36 DEGs in the PPI network module revealed that 34 DEGs (including TOP2A, CCNB1, BIRC5, and TTK) and two miRNAs (miR‑21‑5p and miR‑31‑5p) were significantly associated with NSCLC prognosis.
|
31746439 |
2020 |
|
Renal Cell Carcinoma
|
0.340 |
GeneticVariation
|
disease |
BEFREE |
We observed, after gender stratification and age-adjustment, that BIRC5-31CC and CASP9+83CT/TT genotypes were associated with an increased risk for RCC development in the female group of our southern European study population (aOR=3.85; P=0.019; aOR=2.98; P=0.028; respectively).
|
23645041 |
2013 |
|
Colonic Neoplasms
|
0.340 |
GeneticVariation
|
group |
LHGDN |
Gene therapy for colon cancer by adeno-associated viral vector-mediated transfer of survivin Cys84Ala mutant.
|
15685548 |
2005 |
|
Conventional (Clear Cell) Renal Cell Carcinoma
|
0.320 |
GeneticVariation
|
disease |
BEFREE |
We observed, after gender stratification and age-adjustment, that BIRC5-31CC and CASP9+83CT/TT genotypes were associated with an increased risk for RCC development in the female group of our southern European study population (aOR=3.85; P=0.019; aOR=2.98; P=0.028; respectively).
|
23645041 |
2013 |
|
Endometriosis
|
0.220 |
GeneticVariation
|
disease |
LHGDN |
Transcriptional expression of survivin and its splice variants in endometriosis.
|
16644787 |
2006 |
|
Malignant Neoplasms
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Emerging evidences indicate that polymorphism in BIRC5 promoter (rs9904341) is associated with cancer risk, but the results of individually published studies are inconclusive.
|
24096544 |
2014 |
|
Malignant Neoplasms
|
0.100 |
GeneticVariation
|
group |
BEFREE |
An upgrade risk in rs9904341 of BIRC5 were revealed to be associated with urinary cancer in allele contrast model (OR = 1.222, P = 0.012), homozygote contrast model (OR = 1.579, P = 0.0001) and recessive contrast model (OR = 1.433, P < 0.001), as well as rs2071214 polymorphism in the subgroup analysis of BCa in allele contrast model (OR = 1.362, P = 0.011) and recessive contrast model (OR = 1.417, P = 0.015).
|
31809840 |
2020 |
|
Neoplasms
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Tumors injected with pAd-T34A exhibited loss of proliferating cells and massive apoptosis by in situ internucleosomal DNA fragmentation.
|
11581299 |
2001 |
|
Neoplasms
|
0.100 |
GeneticVariation
|
group |
BEFREE |
TN adenocarcinoma patients in the BIRC5 high-expression group suffered from a significantly high risk of distant metastasis (<i>P</i> = 0.046), advanced N stage (<i>P</i> = 0.033), and tumor-bearing (<i>P</i> = 0.031) and deceased status (<i>P</i> = 0.003).
|
31093306 |
2019 |
|
Neoplasms
|
0.100 |
GeneticVariation
|
group |
BEFREE |
DNA was extracted from tumour samples and genotyped for three BIRC5 promoter single nucleotide polymorphisms (-31G > C, -241C > T and -625G > C).
|
21861135 |
2011 |
|
Periodontitis
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Genome-wide association study of chronic periodontitis in a general German population.
|
24024966 |
2013 |
|
Periodontosis
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Genome-wide association study of chronic periodontitis in a general German population.
|
24024966 |
2013 |
|
Primary malignant neoplasm
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Emerging evidences indicate that polymorphism in BIRC5 promoter (rs9904341) is associated with cancer risk, but the results of individually published studies are inconclusive.
|
24096544 |
2014 |
|
Primary malignant neoplasm
|
0.100 |
GeneticVariation
|
group |
BEFREE |
An upgrade risk in rs9904341 of BIRC5 were revealed to be associated with urinary cancer in allele contrast model (OR = 1.222, P = 0.012), homozygote contrast model (OR = 1.579, P = 0.0001) and recessive contrast model (OR = 1.433, P < 0.001), as well as rs2071214 polymorphism in the subgroup analysis of BCa in allele contrast model (OR = 1.362, P = 0.011) and recessive contrast model (OR = 1.417, P = 0.015).
|
31809840 |
2020 |
|
Neoplasm Metastasis
|
0.090 |
GeneticVariation
|
phenotype |
BEFREE |
Our purpose was to investigate the potential role of BIRC5-31G/C and CASP9+83C/T functional polymorphisms in the risk for the development of RCC and metastatic disease.
|
23645041 |
2013 |
|
Malignant neoplasm of colon and/or rectum
|
0.060 |
GeneticVariation
|
disease |
BEFREE |
Infection with pAd-T34A caused spontaneous apoptosis in cell lines of breast, cervical, prostate, lung, and colorectal cancer.
|
11581299 |
2001 |
|
Malignant neoplasm of colon and/or rectum
|
0.060 |
GeneticVariation
|
disease |
BEFREE |
Synergistic Effect of Simvastatin Plus Radiation in Gastric Cancer and Colorectal Cancer: Implications of BIRC5 and Connective Tissue Growth Factor.
|
26277021 |
2015 |
|
Mesothelioma
|
0.030 |
GeneticVariation
|
disease |
BEFREE |
Our findings indicate no relationship between BIRC5 genotypes and survivin expression or overall survival in mesothelioma patients.
|
21861135 |
2011 |