Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4014722
Disease: STING-ASSOCIATED VASCULOPATHY, INFANTILE-ONSET
STING-ASSOCIATED VASCULOPATHY, INFANTILE-ONSET 		0.740 Biomarker disease CTD_human
CUI: C0206062
Disease: Lung Diseases, Interstitial
Lung Diseases, Interstitial 		0.130 Biomarker group HPO
CUI: C0015967
Disease: Fever
Fever 		0.110 Biomarker phenotype HPO
CUI: C0041834
Disease: Erythema
Erythema 		0.110 Biomarker phenotype HPO
CUI: C0002871
Disease: Anemia
Anemia 		0.100 Biomarker disease HPO
CUI: C0015544
Disease: Failure to Thrive
Failure to Thrive 		0.100 Biomarker disease HPO
CUI: C0023530
Disease: Leukopenia
Leukopenia 		0.100 Biomarker disease HPO
CUI: C0039446
Disease: Telangiectasis
Telangiectasis 		0.100 Biomarker disease HPO
CUI: C0151632
Disease: ESR raised
ESR raised 		0.100 Biomarker phenotype HPO
CUI: C0151669
Disease: Increased antibody level in blood
Increased antibody level in blood 		0.100 Biomarker phenotype HPO
CUI: C0221260
Disease: Dystrophia unguium
Dystrophia unguium 		0.100 Biomarker disease HPO
CUI: C0241157
Disease: pustule
pustule 		0.100 Biomarker phenotype HPO
CUI: C0263401
Disease: Cutis marmorata
Cutis marmorata 		0.100 Biomarker disease HPO
CUI: C0277942
Disease: Butterfly rash
Butterfly rash 		0.100 Biomarker phenotype HPO
CUI: C0456070
Disease: Growth delay
Growth delay 		0.100 Biomarker phenotype HPO
CUI: C0836924
Disease: Thrombocytosis
Thrombocytosis 		0.100 Biomarker disease HPO
CUI: C1855106
Disease: Neonatal onset
Neonatal onset 		0.100 Biomarker phenotype HPO
CUI: C1861403
Disease: Variable expressivity
Variable expressivity 		0.100 Biomarker phenotype HPO
CUI: C3806482
Disease: Recurrent respiratory infections
Recurrent respiratory infections 		0.100 Biomarker phenotype HPO
CUI: C4014733
Disease: Follicular hyperplasia
Follicular hyperplasia 		0.100 Biomarker phenotype HPO
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.010 Biomarker disease BEFREE <b>Results:</b> 3xTg-AD mice dosed orally with MSX have decreased expression of several inflammatory proteins, including, most notably, the AD risk-associated protein 'triggering receptor expressed on myeloid cells-2' (TREM2), and stimulator of interferon genes TMEM173, and suppressor of cytokine signaling-6 (SOCS6). 31583972 2019
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.020 AlteredExpression disease BEFREE (2017) report that the antiviral drug Ganciclovir induces an interferon type I response in microglia through activation of the STING pathway, inhibiting inflammation and leading to protection in a model of multiple sclerosis. 29268089 2017
CUI: C4040879
Disease: STING-associated vasculopathy with onset in infancy
STING-associated vasculopathy with onset in infancy 		0.050 GeneticVariation disease BEFREE STING-associated vasculopathy with onset in infancy (SAVI) is an autoinflammatory disease caused by gain-of-function mutations in TMEM173. 25029335 2014
CUI: C0042769
Disease: Virus Diseases
Virus Diseases 		0.100 Biomarker group BEFREE STING mediates neuronal innate immune response following Japanese encephalitis virus infection. 22470840 2012
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.100 Biomarker group BEFREE STING, nanoparticles, autoimmune disease and cancer: a novel paradigm for immunotherapy? 25521938 2015