IGF1, insulin like growth factor 1, 3479

N. diseases: 1206; N. variants: 36
Disease: Insulin-Like Growth Factor I Deficiency ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1837475
Disease: Insulin-Like Growth Factor I Deficiency
Insulin-Like Growth Factor I Deficiency 		0.800 Biomarker disease BEFREE The GH-IGF1 axis and longevity. The paradigm of IGF1 deficiency. 18359741 2008
CUI: C1837475
Disease: Insulin-Like Growth Factor I Deficiency
Insulin-Like Growth Factor I Deficiency 		0.800 GeneticVariation disease BEFREE The polymorphisms identified in the upstream core polyadenylation signal at IGF1 exon 6 do not cause IGF1 deficiency as well as pre- and postnatal growth impairment, in contrast to previously reported data. 17895313 2007
CUI: C1837475
Disease: Insulin-Like Growth Factor I Deficiency
Insulin-Like Growth Factor I Deficiency 		0.800 Biomarker disease GENOMICS_ENGLAND A novel mutation in a patient with insulin-like growth factor 1 (IGF1) deficiency. 14684690 2003
CUI: C1837475
Disease: Insulin-Like Growth Factor I Deficiency
Insulin-Like Growth Factor I Deficiency 		0.800 GermlineCausalMutation disease ORPHANET A novel mutation in a patient with insulin-like growth factor 1 (IGF1) deficiency. 14684690 2003
CUI: C1837475
Disease: Insulin-Like Growth Factor I Deficiency
Insulin-Like Growth Factor I Deficiency 		0.800 GeneticVariation disease BEFREE We have recently reported a patient with a homozygous partial deletion of the insulin-like growth factor-I (IGF-I) gene, resulting in IGF-I deficiency, insulin resistance, and short stature. 10770174 2000
CUI: C1837475
Disease: Insulin-Like Growth Factor I Deficiency
Insulin-Like Growth Factor I Deficiency 		0.800 Biomarker disease BEFREE IGF-I deficiency is associated with prenatal and post-natal growth failure and may arise primarily as a result of GH receptor/post-receptor abnormalities or defects in the synthesis and transport of IGF-I. 10549306 1999
CUI: C1837475
Disease: Insulin-Like Growth Factor I Deficiency
Insulin-Like Growth Factor I Deficiency 		0.800 GermlineCausalMutation disease ORPHANET Intrauterine growth retardation and postnatal growth failure associated with deletion of the insulin-like growth factor I gene. 8857020 1996
CUI: C1837475
Disease: Insulin-Like Growth Factor I Deficiency
Insulin-Like Growth Factor I Deficiency 		0.800 Biomarker disease GENOMICS_ENGLAND Intrauterine growth retardation and postnatal growth failure associated with deletion of the insulin-like growth factor I gene. 8857020 1996
CUI: C1837475
Disease: Insulin-Like Growth Factor I Deficiency
Insulin-Like Growth Factor I Deficiency 		0.800 Biomarker disease BEFREE The recent biosynthesis of insulin-like growth factor I has enabled the successful treatment of these patients, accelerating their growth, reducing their obesity, and normalizing their metabolic abnormalities resultant from the insulin-like growth factor I deficiency. 8374676 1993
CUI: C1837475
Disease: Insulin-Like Growth Factor I Deficiency
Insulin-Like Growth Factor I Deficiency 		0.800 Biomarker disease CTD_human