Hyperalgesia
|
0.580 |
Biomarker
|
phenotype |
CTD_human |
Cytokine-mediated inflammatory hyperalgesia limited by interleukin-10.
|
7582491 |
1995 |
Hyperalgesia
|
0.580 |
Biomarker
|
phenotype |
CTD_human |
Moreover, rolipram significantly potentiated hyperalgesia induced by carrageenan, bradykinin, TNF alpha, IL-1 beta, IL-6 and IL-8.
|
10401557 |
1999 |
Hyperalgesia
|
0.580 |
Biomarker
|
phenotype |
CTD_human |
The critical role of invading peripheral macrophage-derived interleukin-6 in vincristine-induced mechanical allodynia in mice.
|
18652822 |
2008 |
Hyperalgesia
|
0.580 |
Biomarker
|
phenotype |
RGD |
Effect of tramadol on immune responses and nociceptive thresholds in a rat model of incisional pain.
|
18988309 |
2008 |
Hyperalgesia
|
0.580 |
Biomarker
|
phenotype |
RGD |
Dynamic response to peripheral nerve injury detected by in situ hybridization of IL-6 and its receptor mRNAs in the dorsal root ganglia is not strictly correlated with signs of neuropathic pain.
|
23953943 |
2013 |
Hyperalgesia
|
0.580 |
AlteredExpression
|
phenotype |
BEFREE |
In this study, we tried to investigate behavioral hyperalgesia, the expression of proinflammatory cytokines, such as interleukin-1β (IL-1β), interleukin-6 (IL-6), and tumor necrosis factor-α (TNF-α), and the activation of microglia in the spinal cord and dorsal root ganglion (DRG) in a rat model of surgical plantar incision with or without perioperative fentanyl.
|
29135586 |
2018 |
Hyperalgesia
|
0.580 |
Biomarker
|
phenotype |
BEFREE |
We used mice lacking D5Rs (<i>DRD5KO</i> mice) to show that carrageenan, interleukin 6, as well as BDNF-induced hyperalgesia and priming are reduced specifically in male mice.
|
29167404 |
2018 |
Hyperalgesia
|
0.580 |
Biomarker
|
phenotype |
BEFREE |
The aim of the current study was to investigate the effects of those two modalities on pain behavior and the expression of pro-inflammatory cytokines such as interleukin (IL)-1β and IL-6 and tumor necrosis factor-α (TNF-α) in the spinal cord and dorsal root ganglion (DRG) in a rat model of perioperative fentanyl induced hyperalgesia.
|
29657246 |
2018 |
Hyperalgesia
|
0.580 |
Biomarker
|
phenotype |
BEFREE |
Interleukin-6 Inhibitor Suppresses Hyperalgesia Without Improvement in Osteoporosis in a Mouse Pain Model of Osteoporosis.
|
30666355 |
2019 |
Hyperalgesia
|
0.580 |
Biomarker
|
phenotype |
BEFREE |
Experimental FM caused bilateral hind paw hyperalgesia and augmented serum cortisol and muscle IL-6 concentrations.
|
30785911 |
2019 |
Hyperalgesia
|
0.580 |
Biomarker
|
phenotype |
BEFREE |
Finally, knockdown of the IL-6 receptor signaling subunit glycoprotein 130 (gp130) attenuated both vibration-induced muscle hyperalgesia and downregulation of KV1.4.
|
31335655 |
2019 |
Hyperalgesia
|
0.580 |
Biomarker
|
phenotype |
BEFREE |
Treatment with anti-IL-6 or anti-IL-6R agents seems to alleviate allodynia and hyperalgesia, so it may be a valid option when treating the many conditions involving pathological pain as rheumatoid arthritis.
|
31536783 |
2019 |
Hyperalgesia
|
0.580 |
Biomarker
|
phenotype |
BEFREE |
The involvement of corticotropin-releasing factor (CRF), Type 2 CRF receptor (CRF<sub>2</sub>) and inflammatory cytokine interleukin-6 (IL-6) was also investigated in the gastric hyperalgesia observed in this model.
|
31558322 |
2019 |