IL10, interleukin 10, 3586

N. diseases: 1679; N. variants: 21
Disease: Leishmaniasis, Visceral ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0023290
Disease: Leishmaniasis, Visceral
Leishmaniasis, Visceral 		0.400 Biomarker disease BEFREE At VL diagnosis, co-infected patients showed higher serum levels of interferon-gamma (IFN-gamma) than matched HIV-1 controls without VL, and lower serum concentrations of IL-10 than non-immunocompromised VL controls. 9844050 1998
CUI: C0023290
Disease: Leishmaniasis, Visceral
Leishmaniasis, Visceral 		0.400 Biomarker disease BEFREE These results indicate the production of IL-10 during L. donovani infection, and suggest a role for this cytokine in the regulation of immune responsiveness during visceral leishmaniasis. 8326000 1993
CUI: C0023290
Disease: Leishmaniasis, Visceral
Leishmaniasis, Visceral 		0.400 AlteredExpression disease BEFREE Transcript levels of IL-10 as well as IFN-gamma were significantly elevated in patients with active visceral leishmaniasis; IL-10 levels decreased markedly with resolution of disease. 8097208 1993