Azoospermia
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
Azoospermia associated with a mutation in the ligand-binding domain of an androgen receptor displaying normal ligand binding, but defective trans-activation.
|
9851768 |
1998 |
Azoospermia
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
Results suggest that an increase in the number of CAG repeats in the androgen receptor gene to 31 or greater may be associated with the etiology of at least some cases of idiopathic azoospermia.
|
10604712 |
1999 |
Azoospermia
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
A novel variant of androgen receptor is associated with idiopathic azoospermia.
|
27498682 |
2016 |
Azoospermia
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
Androgen receptor (AR) gene mutations have been shown to cause androgen insensitivity syndrome with altered sexual differentiation in XY individuals, ranging from a partial insensitivity with male phenotype and azoospermia to a complete insensitivity with female phenotype and the absence of pubic and axillary sexual hair after puberty.
|
10999818 |
2000 |
Azoospermia
|
0.200 |
AlteredExpression
|
disease |
BEFREE |
Expression of androgen receptor co-regulators in the testes of men with azoospermia.
|
17919607 |
2008 |
Azoospermia
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
An increase in CAG trinucleotide repeat length in the androgen receptor (AR) gene has been linked to idiopathic azoospermia.
|
12042281 |
2002 |
Azoospermia
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
Sequencing analysis of the first exon in the androgen receptor (AR) gene have shown c.1783C>T mutation in the two patients with azoospermia.
|
28659371 |
2017 |
Azoospermia
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
The aim of this study was to investigate the AR gene mutations in a cohort of males with idiopathic azoospermia referred to Royan Institute.
|
31373714 |
2019 |
Azoospermia
|
0.200 |
AlteredExpression
|
disease |
BEFREE |
Previous studies have shown that total AR knockout would lead to incomplete spermatogenesis and lowered serum testosterone levels in mice, resulting in azoospermia and infertility.
|
29228103 |
2018 |
Azoospermia
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
To assess the contribution of these genetic defects to male infertility, 61 Israeli men with severe oligo- (n = 15) or azoospermia (n = 46), were screened for Y chromosome microdeletions, and the AR-(CAG)n repeat length.
|
12220434 |
2002 |
Azoospermia
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
The first analysis of exon 1 (the transactivation domain) of the androgen receptor gene in infertile men with oligospermia or azoospermia.
|
7926115 |
1994 |
Azoospermia
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
This study provides the first molecular evidence of an abnormality in the androgen receptor gene in a phenotypic male with azoospermia.
|
1750490 |
1991 |
Azoospermia
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
The results of this study confirm the importance of the AZF region in normal spermatogenesis, whereas it shows no link between the length of CAG repeats in the AR gene and male azoospermia in Jordanian group examined.
|
29441603 |
2018 |
Azoospermia
|
0.200 |
Biomarker
|
disease |
HPO |
|
|
|