KRAS, KRAS proto-oncogene, GTPase, 3845

N. diseases: 1213; N. variants: 54
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.700 Biomarker disease BEFREE Our findings indicate that an activated MAPK pathway is critical in tumor growth and survival of ovarian tumors with KRAS or BRAF mutations and suggest that the CI-1040 induced phenotypes depend on the mutational status of KRAS and BRAF in ovarian tumors. 15753399 2005
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.700 Biomarker disease BEFREE The TOV-21G, TOV-81D, OV-90, and TOV-112D cell lines were derived from ovarian tumors (TOV) or ascites (OV) from chemotherapy- and radiotherapy-naive patients and were characterized by their mutation spectrum of BRCA2, TGFbeta-RII, KRAS2, TP53, and CDKN2A. 15258697 2004
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.700 GeneticVariation disease BEFREE K-RAS mutations are the most frequent molecular genetic alteration in serous ovarian tumors of borderline malignancy (SBOT). 12594239 2003
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.700 GeneticVariation disease BEFREE Comparison of mutations of Ki-RAS and p53 immunoreactivity in borderline and malignant epithelial ovarian tumors. 10078924 1999
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.700 GeneticVariation disease BEFREE Analysis of loss of heterozygosity and KRAS2 mutations in ovarian neoplasms: clinicopathological correlations. 9115967 1997
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.700 GeneticVariation disease BEFREE p53 and Ki-ras gene mutations in epithelial ovarian neoplasms. 8319218 1993
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.700 Biomarker disease BEFREE DNA blotting analysis of 64 tumors indicates that trisomy 12 does not seem to be related to K-ras-2 amplification in ovarian tumors. 2071229 1991
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.700 CausalMutation disease CGI
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.700 Biomarker disease HPO