Cardiovascular Diseases
|
0.500 |
Biomarker
|
group |
BEFREE |
Total serum cholesterol (TC), high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C), triglycerides (TG), apolipoprotein A-I (apo A-I), apolipoprotein B (apo B), and lipoprotein (a) (Lp(a)) were analysed in 879 14- and 17-year-old healthy adolescents (477 boys and 402 girls), and related to family history of cardiovascular disease, early feeding, weight and length at birth, and physical growth during infancy and childhood.
|
8546746 |
1995 |
Cardiovascular Diseases
|
0.500 |
GeneticVariation
|
group |
BEFREE |
We assessed the relative importance of lipid, apo B, lipoprotein(a) [Lp(a)], and total homocysteine (tHcy) levels in children in relation to premature cardiovascular disease in family members.
|
8798245 |
1996 |
Cardiovascular Diseases
|
0.500 |
GeneticVariation
|
group |
BEFREE |
A high serum concentration of lipoprotein(a) [Lp(a)] is a significant and independent risk factor for cardiovascular disease.
|
8878554 |
1996 |
Cardiovascular Diseases
|
0.500 |
Biomarker
|
group |
BEFREE |
Elevated serum lipoprotein(a) [Lp(a)] levels increase the risk of cardiovascular disease if levels of low-density lipoproteins (LDLs) are also high.
|
9225824 |
1997 |
Cardiovascular Diseases
|
0.500 |
GeneticVariation
|
group |
BEFREE |
Increased levels of lipoprotein (a) [Lp(a)] have been considered an independent risk factor for cardiovascular disease, but the mechanism behind this relationship is not completely understood.
|
9580386 |
1998 |
Cardiovascular Diseases
|
0.500 |
AlteredExpression
|
group |
BEFREE |
To study the implications of LP(a), we examined plasma LP(a) levels and molecular weights of APO(a) in patients with cerebrovascular disease (CVD) or diabetes mellitus (DM).
|
9701454 |
1998 |
Cardiovascular Diseases
|
0.500 |
Biomarker
|
group |
BEFREE |
Lipoprotein(a) [Lp(a)] has been considered to be a predictor of premature coronary heart disease and other cardiovascular diseases.
|
10098351 |
1999 |
Cardiovascular Diseases
|
0.500 |
GeneticVariation
|
group |
BEFREE |
1.Elevated plasma lipoprotein (a) (Lp(a)) concentrations have been correlated with an increased risk of premature cardiovascular disease.
|
10225140 |
1999 |
Cardiovascular Diseases
|
0.500 |
Biomarker
|
group |
BEFREE |
Family history of early cardiovascular disease in children with moderate to severe hypercholesterolemia: relationship to lipoprotein (a) and low-density lipoprotein cholesterol levels.
|
10072255 |
1999 |
Cardiovascular Diseases
|
0.500 |
GeneticVariation
|
group |
BEFREE |
The elevation of serum or plasma lipoprotein(a) [Lp(a)] levels is regarded as an independent risk factor for cardiovascular disease, and many previous reports demonstrated that Lp(a) levels in hemodialysis patients were significantly higher than in controls.
|
10095177 |
1999 |
Cardiovascular Diseases
|
0.500 |
Biomarker
|
group |
BEFREE |
Abnormally high serum levels of Lp(a) in patients with CVD and VD seemed to be due to specific increases in low-molecular-weight apolipoprotein(a) isoforms in Lp(a).
|
10765043 |
2000 |
Cardiovascular Diseases
|
0.500 |
Biomarker
|
group |
BEFREE |
High lipoprotein(a) (Lp(a)) serum concentrations and the underlying apolipoprotein(a) (apo(a)) phenotypes are risk factors for cardiovascular disease in the general population as well as in patients with renal disease.
|
10616846 |
2000 |
Cardiovascular Diseases
|
0.500 |
Biomarker
|
group |
BEFREE |
Increased lipoprotein(a) [Lp(a)] in plasma is an independent risk factor for premature cardiovascular diseases.
|
10856522 |
2000 |
Cardiovascular Diseases
|
0.500 |
Biomarker
|
group |
BEFREE |
Lipoprotein(a) as a risk factor for maternal cardiovascular disease mortality in kindreds with familial combined hyperlipidemia or familial hypertriglyceridemia.
|
11595020 |
2001 |
Cardiovascular Diseases
|
0.500 |
GeneticVariation
|
group |
BEFREE |
Instability of lipoprotein(a) in plasma stored at -70 degrees C: effects of concentration, apolipoprotein(a) genotype, and donor cardiovascular disease.
|
11514402 |
2001 |
Cardiovascular Diseases
|
0.500 |
Biomarker
|
group |
BEFREE |
High plasma concentrations of lipoprotein (a) [Lp(a)] are now considered a major risk factor for atherosclerosis and cardiovascular disease.
|
11068075 |
2001 |
Cardiovascular Diseases
|
0.500 |
Biomarker
|
group |
BEFREE |
Lipoprotein(a) in American Indians is low and not independently associated with cardiovascular disease. The Strong Heart Study.
|
11880218 |
2002 |
Cardiovascular Diseases
|
0.500 |
Biomarker
|
group |
BEFREE |
The lipoprotein Lp(a) with high plasma concentration is an independent genetic determinant for cardiovascular diseases.
|
12127051 |
2002 |
Cardiovascular Diseases
|
0.500 |
Biomarker
|
group |
BEFREE |
Lipoprotein (a) in obese children with a family history of cardiovascular disease.
|
11822583 |
2002 |
Cardiovascular Diseases
|
0.500 |
Biomarker
|
group |
BEFREE |
Lipoprotein(a) as a potent risk indicator for early cardiovascular disease.
|
12578287 |
2002 |
Cardiovascular Diseases
|
0.500 |
Biomarker
|
group |
BEFREE |
Report of the National Heart, Lung, and Blood Institute Workshop on Lipoprotein(a) and Cardiovascular Disease: recent advances and future directions.
|
14578310 |
2003 |
Cardiovascular Diseases
|
0.500 |
GeneticVariation
|
group |
BEFREE |
Therefore, in the evaluation of a fully automated, particle-enhanced turbidimetric immunoassay for the measurement of lipoprotein(a) we have determined its reference interval in the Spanish population, an area with the lowest incidence of cardiovascular disease in Europe.
|
12633762 |
2003 |
Cardiovascular Diseases
|
0.500 |
GeneticVariation
|
group |
BEFREE |
Other key aspects of lipoprotein metabolism and cardiovascular disease risk such as apolipoprotein B-100, the LDL receptor, apolipoprotein C-III or apolipoprotein (a) will be updated.
|
12589187 |
2003 |
Cardiovascular Diseases
|
0.500 |
GeneticVariation
|
group |
BEFREE |
Elevated lipoprotein(a) [Lp(a)] levels are a recognized risk factor for cardiovascular disease; however, little is known about their effects on venous thromboembolism.
|
14656611 |
2003 |
Cardiovascular Diseases
|
0.500 |
AlteredExpression
|
group |
BEFREE |
Male gender (RR 2.82, 95% CI 2.37-3.36), smoking (RR 1.67, 95% CI 1.40-1.99), hypertension (RR 1.36, 95% CI 1.06-1.75), diabetes mellitus (RR 2.19, 95% CI 1.36-3.54), low HDL-C (RR 1.37, 95% CI 1.15-1.63) and elevated lipoprotein(a) levels (RR 1.50, 95% CI 1.20-1.79) proved to be independent CVD risk factors.
|
15554949 |
2004 |