|
Patent ductus arteriosus
|
0.010 |
Biomarker
|
disease |
BEFREE |
Our results show that MBTS with nonclosure of PDA is accompanied by lower blood velocity, energy loss and WSS values at the MBT shunt; smaller vortex regions; higher oxygen content(Sao<sub>2</sub>) and PA flow; and more uniform velocity distribution in the LPA and RPA than MBTS with closure of PDA.
|
31760306 |
2020 |
|
Fatigue
|
0.010 |
GeneticVariation
|
phenotype |
BEFREE |
Our results show that MBTS with nonclosure of PDA is accompanied by lower blood velocity, energy loss and WSS values at the MBT shunt; smaller vortex regions; higher oxygen content(Sao<sub>2</sub>) and PA flow; and more uniform velocity distribution in the LPA and RPA than MBTS with closure of PDA.
|
31760306 |
2020 |
|
Tricuspid Valve Insufficiency
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Device- or procedure-related complications were reported in nine patients (8.9%) including three LPA stenoses (requiring surgery in two and balloon dilatation in one), two neo-coarctations (one requiring subsequent surgery), and three instances of tricuspid valve regurgitation at follow-up.
|
31609068 |
2020 |
|
Anhedonia
|
0.010 |
Biomarker
|
disease |
BEFREE |
Contrary to our expectations, the continuous delivery of LPA in chronically stressed animals potentiated rather than inhibited some (e.g., anhedonia, reduced latency to the first immobility period), though not all, behavioural effects of stress.
|
31811875 |
2020 |
|
Premature aging syndrome
|
0.010 |
Biomarker
|
disease |
BEFREE |
Here, we study the roles of LPA and LPA receptors in premature aging.
|
31714004 |
2020 |
|
Colitis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Using LPA receptor knockout mice, we previously uncovered a role for LPA signaling in promoting colitis and colorectal cancer.
|
30481488 |
2019 |
|
Focal glomerulosclerosis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Apolipoprotein A-Ib as a biomarker of focal segmental glomerulosclerosis recurrence after kidney transplantation: diagnostic performance and assessment of its prognostic value - a multi-centre cohort study.
|
30411406 |
2019 |
|
Heart valve disease
|
0.010 |
Biomarker
|
group |
BEFREE |
Lipoprotein(a) as a risk factor for calcific aortic valvulopathy in heterozygous familial hypercholesterolemia.
|
30616181 |
2019 |
|
Seizures
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
For example, stimulation of presynaptic LPA receptors in hippocampal neurons regulates glutamate release from the presynaptic terminal, and excess of LPA induce seizures.
|
31191247 |
2019 |
|
Dermatologic disorders
|
0.010 |
Biomarker
|
group |
BEFREE |
Pharmacological inhibition of LPA synthesis or antagonization of LPA receptors is a new strategy for the treatment of various skin disorders.
|
30584899 |
2019 |
|
Tuberculosis, Pulmonary
|
0.010 |
Biomarker
|
disease |
BEFREE |
In the present study, LPA efficacy was assayed in detection and drug susceptibility testing of pulmonary tuberculosis in comparison to available methods in Iran and phylogenetic analyses of isolated cases carried out by MIRU-VNTR.
|
31814746 |
2019 |
|
Self-Injurious Behavior
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
The plasma proteomic analysis showed that apolipoprotein A-IV (Apo A-IV ) was downregulated by 2.63-fold (confidence interval: 1.52-4.54) in individuals with deliberate self-harm (n=10) compared to matched controls, which was consistent in mass spectrometry-based relative quantification and Western blot analysis performed in an independent set of individuals with deliberate self-harm (n=18).
|
31823918 |
2019 |
|
Antiphospholipid Syndrome
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Thrombophilia screening involved inherited thrombophilia (factor V Leiden, prothrombin G20210A mutation, deficiency of protein C, protein S or antithrombin), antiphospholipid syndrome (APS), along with factor VIII >150%, homocysteine ≥15 μM and lipoprotein (a) >30 mg/dl.
|
31133433 |
2019 |
|
Pancreatic carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
N-WASP Control of LPAR1 Trafficking Establishes Response to Self-Generated LPA Gradients to Promote Pancreatic Cancer Cell Metastasis.
|
31668663 |
2019 |
|
Chronic heart failure
|
0.010 |
Biomarker
|
disease |
BEFREE |
High Level of Lipoprotein(a) as Predictor for Recurrent Heart Failure in Patients with Chronic Heart Failure: a Cohort Study.
|
31340235 |
2019 |
|
Impaired glucose tolerance
|
0.010 |
AlteredExpression
|
phenotype |
BEFREE |
We found that the serum ADMA and C-reactive protein levels were significantly increased in IGT and diabetic patients, whereas the levels of lipoprotein A and adiponectin were decreased, especially in diabetic patients with obesity.
|
30536533 |
2019 |
|
Antithrombin III Deficiency
|
0.010 |
Biomarker
|
disease |
BEFREE |
Recurrence rates calculated per 100 person-years were 10 (95% CI: 3-24) for antithrombin deficiency, 6 (95% CI: 4-9) for elevated lipoprotein (a), and 13 (95% CI: 7-20) for the presence of more than one prothrombotic risk factor.
|
30679327 |
2019 |
|
Cerebral venous sinus thrombosis
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Elevated lipoprotein(a) as a new risk factor of cerebral venous sinus thrombosis: association with fibrin clot properties.
|
30511257 |
2019 |
|
Malignant neoplasm of pancreas
|
0.010 |
Biomarker
|
disease |
BEFREE |
N-WASP Control of LPAR1 Trafficking Establishes Response to Self-Generated LPA Gradients to Promote Pancreatic Cancer Cell Metastasis.
|
31668663 |
2019 |
|
Sleep Apnea, Obstructive
|
0.010 |
Biomarker
|
disease |
BEFREE |
Effect of the Interaction between Obstructive Sleep Apnea and Lipoprotein(a) on Insulin Resistance: A Large-Scale Cross-Sectional Study.
|
31089476 |
2019 |
|
Cardiac defects
|
0.010 |
Biomarker
|
group |
BEFREE |
Children with 22q11.2DS without cardiac defects show smaller LPA compared with healthy subjects.
|
30933971 |
2019 |
|
Apraxia, Developmental Verbal
|
0.010 |
Biomarker
|
disease |
BEFREE |
For example, inflammatory factors including C-reactive protein and cytokines, lipoprotein (a), and cystatin-C might be precipitating factor for CAS.
|
31637257 |
2019 |
|
Spondylarthritis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Information on lipoprotein(a) [Lp(a)], a non-conventional risk factor, in SpA is scarce.
|
30789151 |
2019 |
|
Cutaneous Mastocytosis
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Cholesterol content of the lipoprotein (a) peak was significantly higher in the hyper-CM groups compared to non-CM phenotypes (<i>p</i> < 0.0001).
|
31572464 |
2019 |
|
Hepatitis B Virus-Related Hepatocellular Carcinoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Diagnostic and prognostic significance of mRNA expressions of apolipoprotein A and C family genes in hepatitis B virus-related hepatocellular carcinoma.
|
31211449 |
2019 |