|
Coronary heart disease
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Influence of lipoprotein lipase serine 447 stop polymorphism on tracking of triglycerides and HDL cholesterol from childhood to adulthood and familial risk of coronary artery disease: the Bogalusa heart study.
|
11730816 |
2001 |
|
Coronary heart disease
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The LPL polymorphism contributed to the severity of coronary disease in patients with MS and recent ACS.
|
29412239 |
2018 |
|
Coronary heart disease
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Functional significance of lipoprotein lipase HindIII polymorphism associated with the risk of coronary artery disease.
|
18242618 |
2008 |
|
Coronary heart disease
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The S447X polymorphism of lipoprotein lipase: effect on the incidence of premature coronary disease and on plasma lipids.
|
17533471 |
2007 |
|
Coronary heart disease
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The Asn9 variant of lipoprotein lipase is associated with the -93G promoter mutation and an increased risk of coronary artery disease. The Regress Study Group.
|
9550358 |
1998 |
|
Coronary heart disease
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Two common coding sequence mutations of lipoprotein lipase (serine447-ter, producing a carboxy terminal truncation; and asp9-asn variants) were studied in 329 Caucasian subjects, of whom 243 had angiographic features of premature atheroscelerosis (220 with coronary artery disease; 23 with coronary and peripheral artery disease).
|
8835323 |
1995 |
|
Coronary heart disease
|
0.400 |
Biomarker
|
disease |
BEFREE |
Associations for lipoprotein lipase and peroxisome proliferator-activated receptor-gamma gene and coronary artery disease in an Indian population.
|
20430250 |
2010 |
|
Coronary heart disease
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
LPL Pvull rare allele homozygote status seems to be beneficial with more favorable lipid changes and protection against CHD.
|
16419488 |
2005 |
|
Coronary heart disease
|
0.400 |
Biomarker
|
disease |
BEFREE |
We review the evidence for the role of apolipoprotein E, lipoprotein lipase and interleukin-6 in CHD and their interaction with smoking (an environmental risk).
|
12542551 |
2003 |
|
Coronary heart disease
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The LPL S447X variant tended to be associated with lower TG and higher HDL-C levels, and lower risk of CHD in all 3 cohorts.
|
19185650 |
2009 |
|
Coronary heart disease
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Genetic variants of the lipoprotein lipase gene have been associated with dyslipidemia and coronary artery disease.
|
10974229 |
2000 |
|
Coronary heart disease
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The multivariate model included 512 men with coronary artery disease from the REGRESS study who were completely genotyped for eight polymorphisms selected in the univariate procedure (ie, APOA1 G(-75)A, ABCA1 C(-477)T, ABCA1 G1051A, APOC3 T3206G, APOE Arg158Cys, LIPC C(-514)T, LPL Asn291Ser and LPL Ser447Stop).
|
15657615 |
2005 |
|
Coronary heart disease
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The LPL S447X cSNP is associated with decreased blood pressure and plasma triglycerides, and reduced risk of coronary artery disease.
|
11683775 |
2001 |
|
Coronary heart disease
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Our results suggest that the LPL gene is involved in the determination of lipoprotein profiles, the predisposition to CHD, and the severity of atherosclerosis.
|
8576640 |
1995 |
|
Coronary heart disease
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Lipoprotein lipase gene mutations in coronary artery disease.
|
9627528 |
1998 |
|
Coronary heart disease
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Relative contribution of low-density lipoprotein receptor and lipoprotein lipase gene mutations to angiographically assessed coronary artery disease among French Canadians.
|
9708657 |
1998 |
|
Coronary heart disease
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Novel LPL mutation (L303F) found in a patient associated with coronary artery disease and severe systemic atherosclerosis.
|
12641539 |
2003 |
|
Coronary heart disease
|
0.400 |
Biomarker
|
disease |
BEFREE |
Synergistic effect between lipoprotein lipase and apolipoprotein C3 genes in determining the severity of coronary artery disease.
|
23377670 |
2013 |
|
Coronary heart disease
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The LPL Ser447Stop (S447X) allele is associated with anti-atherogenic lipid profiles and a modest reduction in risk for coronary disease.
|
16822320 |
2006 |
|
Coronary heart disease
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Lipoprotein lipase gene PvuII polymorphism serum lipids and risk for coronary artery disease: meta-analysis.
|
17473385 |
2007 |
|
Coronary heart disease
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Lack of association of lipoprotein lipase gene polymorphisms with coronary artery disease in the Saudi Arab population.
|
12708905 |
2003 |
|
Coronary heart disease
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Regulatory mutations in the human lipoprotein lipase gene in patients with familial combined hyperlipidemia and coronary artery disease.
|
9017514 |
1996 |
|
Coronary heart disease
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The entire coding and boundary regions of LPL and HTGL genes were analyzed by direct sequencing in 20 patients with both LHDL/HTG and diagnosed CHD.
|
10729390 |
2000 |
|
Coronary heart disease
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Hyperlipidemia is a risk factor of arteriosclerosis, stroke, and other coronary heart disease, which has been shown to correlate with single nucleotide polymorphisms of genes essential for lipid metabolism, such as lipoprotein lipase (LPL) and apolipoprotein A5 (APOA5).
|
29425239 |
2018 |
|
Coronary heart disease
|
0.400 |
Biomarker
|
disease |
BEFREE |
The role of plasma lipoprotein lipase, hepatic lipase and GPIHBP1 in the metabolism of remnant lipoproteins and small dense LDL in patients with coronary artery disease.
|
29174344 |
2018 |