|
Autistic Disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
Individuals with autism/ASD have various kinds of needs but all want acceptance and most deserve better accommodations.
|
28275086 |
2017 |
|
Autistic Disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
Fifty-eight parents with a blood relative with Autism (who happened to be an offspring with ASD in all cases) and a TD child completed the Autism Quotient, demographic and psychological information, as well as reporting on Parenting Sense of Competence, the Parent-Child Relationship, and Parenting Needs.
|
30877419 |
2019 |
|
Autistic Disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
The results suggest that children with ASD might be impaired in their ability to predict and infer the consequences of others' movements, which could be related to the social-communicative deficits often reported in autism.
|
28979000 |
2017 |
|
Autistic Disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
Two laboratories have reported that children with ASD are less likely than their typical peers to fill pauses with um but their use of uh is unaffected (Irvine et al., J Autism Dev Disord 46(3):1061-1070, 2016; Gorman et al., Autism Res 9(8):854-865, 2016).
|
30171507 |
2018 |
|
Autistic Disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
© 2018 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: This was the first study to investigate the development of three well-known cognitive functions into adolescence: While the understanding of other's minds improves from childhood to adolescence, adolescents with ASD are still impaired relative to their peers.
|
30265774 |
2018 |
|
Autistic Disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
Behavioral predictors of autism recurrence are genetically independent and influence social reciprocity: evidence that polygenic ASD risk is mediated by separable elements of developmental liability.
|
31439834 |
2019 |
|
Autistic Disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
We examined associations between maternal opioid prescriptions preconception to delivery (peri-pregnancy) and child's risk of ASD, developmental delay/disorder (DD) with no ASD features, or ASD/DD with autism features in the Study to Explore Early Development, a case-control study of neurodevelopment.
|
30132098 |
2019 |
|
Autistic Disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
's (Journal of Autism and Developmental Disabilities 43:1236-1242, 2013) investigation among a sample of 45 high ability children and adolescents diagnosed with ASD under DSM-IV-TR.
|
27885547 |
2017 |
|
Autistic Disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
The availability of large and comprehensive registries that include detailed phenotype and genetic information for individuals affected with an ASD and family members is crucial for the discovery of autism susceptibility genes and the development and application of biologically based approaches to diagnosis and treatment.
|
20955925 |
2010 |
|
Autistic Disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
Further studies of mouse KO models of ASD genes such as Sema 3F or NRP2 may be informative to clinical phenotypes contributing to the pathogenesis in autism and epilepsy patients.
|
30635860 |
2019 |
|
Autistic Disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
Our results show that in adolescents with autism JA is subserved by abnormal activation patterns in brain areas related to social cognition abnormalities which are at the core of ASD including the STS and TPJ, despite behavioral maturation with no behavioral differences.
|
28180069 |
2017 |
|
Autistic Disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
For multivariate analysis, forward stepwise logistic regression model was employed to examine the association between autism and the chances that the child develops ASD to assess the odds ratios.
|
30554347 |
2019 |
|
Autistic Disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
Autism spectrum disorder (ASD or autism) is a neurodevelopmental condition that affects over 1% of the population worldwide.
|
29496150 |
2018 |
|
Autistic Disorder
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
A common molecular signature in ASD gene expression: following Root 66 to autism.
|
26731442 |
2016 |
|
Autistic Disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
The study's limitations, the use of the SCAS-P to screen for DSM-derived anxiety problems in ASD and future research directions are discussed.Autism Res 2017, 10: 1629-1652.
|
28574646 |
2017 |
|
Autistic Disorder
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Since that time, with the growth of genetic investigations particularly in the area of pediatric development, an increasing number of children with autism and related disorders (autistic spectrum disorders, ASD) have been the subject of genetic studies both in the clinical setting and in the wider research environment.
|
27012322 |
2016 |
|
Autistic Disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
This study aims to determine the prevalence of autistic traits or ASD in adults with GD using two different data collection methods: (1) cross-sectional data using the social responsiveness scale-adults (SRS-A) and the autism quotient (AQ) (n = 63).(2) Clinical chart data (n = 532).
|
29427119 |
2018 |
|
Autistic Disorder
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Serotonin as modulator of behavior and implication of serotonergic dysfunction in ASD etiology corroborates that serotonergic system genes are potential candidates for autism susceptibility.
|
24291416 |
2014 |
|
Autistic Disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
Findings suggest a wide range of co-occurring psychopathology and high degree of maladaptive behavior among minimally verbal children and adolescents with ASD, which are not directly attributable to autism symptom severity, intellectual disability or limitations in adaptive functioning.
|
30833910 |
2019 |
|
Autistic Disorder
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
These results have significant implications for understanding the neural basis of autism and related neurodevelopmental disorders.<b>SIGNIFICANCE STATEMENT</b> The recurrent ∼600 kb deletion at 16p11.2 (BP4-BP5) is one of the most common genetic etiologies of ASD and, more generally, of neurodevelopmental disorders.
|
31270155 |
2019 |
|
Autistic Disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
Specifically, people with autism have a reduction in parvalbumin (PV)-containing interneurons in the PFC, leading to the suggestion that restoring interneuron function in this region may be a novel therapeutic approach for ASD.
|
29453447 |
2018 |
|
Autistic Disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
ASD is a clinically heterogeneous disorder with great genetic complexity; only through an integrated multidimensional effort can modern autism research progress further.
|
27084239 |
2016 |
|
Autistic Disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
Using mother scores 36% of children with ASD scored below the autism diagnostic cutoff, and 75% scored below the cutoff based on teacher scores.
|
29188585 |
2018 |
|
Autistic Disorder
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Then the evidence for a dysfunctional amygdala in autism is presented with a focus on alterations in development, prenatal valproic acid exposure as a model for ASD, and changes in the oxytocin system therein.
|
29660417 |
2018 |
|
Autistic Disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
A total of 320 parents (age 50+ years) of adult children diagnosed with ASD were recruited from autism organizations and support groups and completed a web-based survey.
|
29982655 |
2019 |