|
Brain Ischemia
|
0.010 |
Biomarker
|
disease |
BEFREE |
To permit the clinical translation of preclinical data, we aimed to define the specific contributions of MBL-A and MBL-C to brain ischemia.
|
30967639 |
2020 |
|
Turner Syndrome
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Here we assessed polymorphisms in CTLA-4 +49A/G (rs231775), PTPN22 +1858G/A (rs2476601), and MBL2 -550 (H/L) (rs11003125), -221(X/Y) (rs7096206) and exon 1 (A/O) in women from northeastern Brazil to determine whether polymorphisms within these key immune response genes confer differential susceptibility to clinical conditions in TS.
|
30508004 |
2020 |
|
C3 Glomerulonephritis
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
He also carried complement factor H (c.2808G>T; p.Glu936Asp) and mannose-binding lectin (c.161G>A; p.Gly54Asp), putting the patient at an increased risk of infections, which was an important trigger for C3 glomerulonephritis.
|
31014550 |
2020 |
|
Malignant neoplasm of endometrium
|
0.010 |
Biomarker
|
disease |
BEFREE |
X chromosome-linked long noncoding RNA lnc-XLEC1 regulates c-Myc-dependent cell growth by collaborating with MBP-1 in endometrial cancer.
|
30698832 |
2019 |
|
Dermatitis
|
0.010 |
Biomarker
|
disease |
BEFREE |
The reduced skin inflammation in MBL<sup>-/-</sup> mice was associated with the decreased infiltration of neutrophils.
|
31260126 |
2019 |
|
Hemophilia A
|
0.010 |
Biomarker
|
disease |
BEFREE |
Investigation of the association between the inhibitor development in hemophilia A and MBL2-SNPs.
|
31141731 |
2019 |
|
Liver neoplasms
|
0.010 |
AlteredExpression
|
group |
BEFREE |
We observed that the human hepatoma cell line HuH7.5, which is routinely used for the study of hepatotropic viruses, is deficient in expression of MBL, ficolin-2 and ficolin-3.
|
30747617 |
2019 |
|
Lyme Disease
|
0.010 |
Biomarker
|
disease |
BEFREE |
The role of Mannose Binding Lectin in the immune response against Borrelia burgdorferi sensu lato.
|
30723261 |
2019 |
|
Mycoses
|
0.010 |
AlteredExpression
|
group |
BEFREE |
This review focuses on a family of fungal transcription factors (Swi4/Mbp1, APSES, Xbp1, Bqt4) derived from the lateral gene transfer of a KilA-N domain commonly found in prokaryotic and eukaryotic DNA viruses.
|
31600629 |
2019 |
|
Oral Manifestations
|
0.010 |
GeneticVariation
|
phenotype |
BEFREE |
The study evaluated the effects of MBL-2 polymorphisms with the oral manifestations of the HSV in human immunodeficiency virus (HIV)-infected patients.
|
31001794 |
2019 |
|
Periodontal Diseases
|
0.010 |
Biomarker
|
group |
BEFREE |
Influence of the treatment of periodontal disease in serum concentration of sirtuin 1 and mannose-binding lectin.
|
31749165 |
2019 |
|
Systemic Scleroderma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Furthermore, patients with SSc renal crisis harbored higher MBL levels (mean 2.7 vs. 1.5 μg/mL, p = 0.04).
|
30885245 |
2019 |
|
Sporotrichosis
|
0.010 |
Biomarker
|
disease |
BEFREE |
We investigated the association of <i>MBL</i> and <i>MASP-2</i> variants with sporotrichosis in a Chinese population and revealed one rare heterozygous mutation in a disseminated cutaneous patient without immunosuppressive conditions (<i>MASP2</i>, p.156_159dupCHNH).
|
31549610 |
2019 |
|
Erythema
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
Our data showed that MBL-deficient (MBL<sup>-/-</sup> ) mice exhibited attenuated skin damage characterized by greatly decreased erythema compared with wild-type control mice during the early stages of IMQ-induced psoriasis-like skin inflammation.
|
31260126 |
2019 |
|
T-Cell Lymphoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Implanted MBL2 T-cell lymphomas in IL-10KO mice were 50% smaller, accompanied by decreased numbers of infiltrating macrophages and reduced efficiency of M2-polarization compared with wild-type mice.
|
30277131 |
2019 |
|
Hepatic necrosis
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
After APAP treatment, MBL-deficient (MBL<sup>-/-</sup> ) mice had significantly higher mortality and aggravated hepatic necrosis as well as elevated serum lactate dehydrogenase and alanine aminotransferase levels compared to control mice.
|
30706943 |
2019 |
|
Diabetes, Autoimmune
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
We compared these characteristics of all adults with and without MBL ≤50 ng/mL: age; sex; body mass index; upper/lower respiratory tract infection; diabetes; autoimmune condition(s); atopy; other allergy; corticosteroid therapy; and subnormal serum IgG subclasses, IgA, and IgM.
|
31117958 |
2019 |
|
Severe hereditary factor VIII deficiency disease
|
0.010 |
Biomarker
|
disease |
BEFREE |
The role of variant alleles of the mannose-binding lectin in the inhibitor development in severe hemophilia A.
|
31141731 |
2019 |
|
Childhood Solid Neoplasm
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
Mannose binding lectin and prediction of risk for chemotherapy induced febrile neutropenia in patients with a solid tumor.
|
30907154 |
2019 |
|
Adult Solid Neoplasm
|
0.010 |
Biomarker
|
group |
BEFREE |
Mannose binding lectin and prediction of risk for chemotherapy induced febrile neutropenia in patients with a solid tumor.
|
30907154 |
2019 |
|
Lupus anticoagulant disorder
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
We observed significantly (a) <i>higher</i> protein levels of total C4, C4A, C4B, C3, and anticardiolipin (ACLA) IgG, (b) increased frequencies of lupus anticoagulant and males, and (c) decreased levels of complement factor H, MBL and ACLA-IgM among patients with thrombosis than those without thrombosis (<i>N</i> = 288).
|
31134052 |
2019 |
|
Skin callus
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Sodium chloride (NaCl) induced expression of a jacalin-related mannose-binding lectin (<i>JRL</i>) gene in leaves, roots, and callus cultures of <i>Populus euphratica</i> (salt-resistant poplar).
|
30769802 |
2019 |
|
Endometrial Carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
X chromosome-linked long noncoding RNA lnc-XLEC1 regulates c-Myc-dependent cell growth by collaborating with MBP-1 in endometrial cancer.
|
30698832 |
2019 |
|
skin damage
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
Our data showed that MBL-deficient (MBL<sup>-/-</sup> ) mice exhibited attenuated skin damage characterized by greatly decreased erythema compared with wild-type control mice during the early stages of IMQ-induced psoriasis-like skin inflammation.
|
31260126 |
2019 |
|
Respiratory Distress Syndrome
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
MBL2 variant-type and mannose-binding lectin deficiency are important risk factors for respiratory distress syndrome development in preterm infants.
|
31029683 |
2019 |