Adult Rhabdomyosarcoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Interestingly, IGF1 does not enhance myogenin expression in Rhabdomyosarcoma-derived RD cells.
|
10973962 |
2000 |
Adult Rhabdomyosarcoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
We showed both rhabdomyosarcoma and rhabdomyosarcomatous areas of the urothelial carcinoma were positive for myogenin, negative for cytokeratin and chromogranin stains.
|
21762516 |
2011 |
Adult Rhabdomyosarcoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Furthermore, the regulatory-gene analyses indicated that these 2 sublines represented 2 distinct differentiation stages of myoblasts, and that MyoD1 and myogenin could serve as the lineage marker and the differentiation marker, respectively, of human rhabdomyosarcoma.
|
1313401 |
1992 |
Adult Rhabdomyosarcoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
CARM1 activates myogenin gene via PCAF in the early differentiation of TPA-induced rhabdomyosarcoma-derived cells.
|
20213728 |
2010 |
Adult Rhabdomyosarcoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
It is one of the pediatric small round blue cell tumors, characterized by strong membrane expression of CD99 in a chain-mail pattern and negativity for lymphoid (CD45), rhabdomyosarcoma (myogenin, desmin, actin) and neuroblastoma (neurofilament protein) markers.
|
16720851 |
2006 |
Adult Rhabdomyosarcoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
By using cryosections of tumor specimens and immunohistochemistry, in the present study we show that strong expression of myogenin in rhabdomyosarcoma is associated with alveolar histology (P = <0.0001, Fisher's exact test).
|
10666368 |
2000 |
Adult Rhabdomyosarcoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Immunohistochemical analysis with a panel of antibodies including antibodies against myogenin and alpha-inhibin is very important to diagnose the rhabdomyosarcoma and to grade the SLCT accurately.
|
16979522 |
2006 |
Adult Rhabdomyosarcoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
MEK inhibition induces MYOG and remodels super-enhancers in RAS-driven rhabdomyosarcoma.
|
29973406 |
2018 |
Adult Rhabdomyosarcoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
The authors conclude that mRNA of the fetal type AChR but not myogenin is a highly specific and sensitive target for the PCR-based diagnosis of RMS.
|
9836066 |
1998 |
Adult Rhabdomyosarcoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Strategies to increase myogenin expression and block IL-4 could simultaneously reduce growth and migration, and enhance terminal differentiation of rhabdomyosarcoma, thus contributing to the control of tumor growth and metastatic spread.
|
19372547 |
2009 |
Adult Rhabdomyosarcoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
To assess the value of myogenin staining and molecular testing in the diagnosis of rhabdomyosarcoma, the authors examined 109 rhabdomyosarcoma samples (45 ARMS samples and 64 ERMS samples).
|
15536621 |
2004 |
Adult Rhabdomyosarcoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Overexpression of the chimera led to continuous expression of MYOD and MYOG-two myogenic markers that are overexpressed in rhabdomyosarcoma cells.
|
24089019 |
2013 |
Adult Rhabdomyosarcoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
In this retrospective analysis, diffuse immunohistochemical reactivity for myogenin in RMS correlates with decreased RFI and OS, independent of histologic subtype, translocation status, tumor site, or stage.
|
18708938 |
2008 |
Adult Rhabdomyosarcoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Amongst the transcripts differentially expressed in the RD cells, MYOD and MYOG (2 fold, p<0.05), and six MYOD downstream targets were up-regulated in RD but not C2C12 cells.
|
23717650 |
2013 |