|
Anemia, Sickle Cell
|
0.010 |
Biomarker
|
disease |
BEFREE |
Brain-derived neurotrophic factor (BDNF) is a nerve growth factor associated with neuronal survival, synaptic plasticity, elevated transcranial Doppler (TCD) velocities and increased risk of stroke in patients with SCD.
|
31736231 |
2020 |
|
Constipation
|
0.010 |
AlteredExpression
|
phenotype |
BEFREE |
TRPV1, GDNF, and NGF mRNA levels were significantly increased in those with IBS-constipation compared to those in controls (all <i>P</i> < 0.05).
|
31623029 |
2020 |
|
Mucocutaneous Lymph Node Syndrome
|
0.010 |
Biomarker
|
disease |
BEFREE |
Furthermore, serum nerve growth factor (NGF) was significantly elevated in LCWE-injected mice, similar to children with KD vasculitis, associated with increased neural remodeling of the myocardium.
|
31758701 |
2020 |
|
Vasculitis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Furthermore, serum nerve growth factor (NGF) was significantly elevated in LCWE-injected mice, similar to children with KD vasculitis, associated with increased neural remodeling of the myocardium.
|
31758701 |
2020 |
|
Cutaneous hypersensitivity
|
0.010 |
Biomarker
|
disease |
BEFREE |
MC-derived tumor necrosis factor (TNF) induces nerve growth factor (NGF) and participates in nerve fiber elongation in skin hypersensitivity.
|
31837249 |
2020 |
|
Anaplasia
|
0.010 |
Biomarker
|
disease |
BEFREE |
NGF alone promoted cell dedifferentiation and redifferentiation mainly towards neurons rather than towards glial cells, related to TrkA and PI3K/Akt signals.
|
30578789 |
2019 |
|
Tooth Attrition
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Tooth wear in 4-week rats was associated with reduced NGF expression and significantly decreased CGRP axons within affected odontoblast regions.
|
30099752 |
2019 |
|
Bone Marrow Diseases
|
0.010 |
Biomarker
|
group |
BEFREE |
Sciatic nerves in diabetic mice showed increased histopathology score, increased silver staining for the nerves-indicating myelopathy- and a decrease in immunostaining for nerve growth factor.
|
30785087 |
2019 |
|
Cartilage Diseases
|
0.010 |
Biomarker
|
group |
BEFREE |
NGF in osteochondral channels and osteoclast densities in subchondral bone were higher in the symptomatic chondropathy group than in the asymptomatic chondropathy group (P < 0.01 and P = 0.02, respectively), as were synovitis scores (P < 0.01).
|
30663865 |
2019 |
|
Allergic Conjunctivitis
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Evidence showed that local and systemic NGF levels increase in patients with allergic conjunctivitis, including allergic rhinoconjuncivitis, vernal keratoconjunctivitis and atopic keratoconjunctivitis.
|
31145195 |
2019 |
|
Coronary Arteriosclerosis
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
In adult rats, lentivirus-mediated short-hairpin RNA targeted at reducing NGF gene expression (NGF-shRNA) or a transient receptor potential vanilloid 1 (TRPV1) antagonist (capsazepine) was injected intrathecally before myocardial ischaemia-reperfusion.
|
31383364 |
2019 |
|
Diabetes Mellitus, Insulin-Dependent
|
0.010 |
Biomarker
|
disease |
BEFREE |
The aim of this investigation was twofold: (1) to determine if sensory neuropathy affects the bone marrow in a mouse model of type 1 diabetes, with consequences for stem cell liberation after tissue injury; and (2) to verify if a single systemic injection of the NGF gene exerts long-term beneficial effects on these phenomena.
|
31016359 |
2019 |
|
External exotoses
|
0.010 |
Biomarker
|
disease |
BEFREE |
However, NGF could activate more proliferation and differentiation genes in the process of chondrogenesis of MSCs, whereas TGF-β1 caused osteophyte formation by activating THBS1 and THBS2.
|
31066473 |
2019 |
|
Fibrosarcoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Nerve growth factor (NGF) has an anti-tumor effects through perivascular innervation of neovessels in HT1080 fibrosarcoma and HepG2 hepatitis tumor in nude mice.
|
31178329 |
2019 |
|
Glycogen storage disease type II
|
0.010 |
Biomarker
|
disease |
BEFREE |
Immunohistochemical localization of NGF, BDNF, and their receptors in a normal and AMD-like rat retina.
|
30871541 |
2019 |
|
Sensorineural Hearing Loss (disorder)
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
The closure rates of tympanic membrane perforations treated with bFGF were reported to be comparable to those following conventional tympanoplasty.For sensorineural hearing loss after blast exposure, treatment with neurotrophic factors, such as nerve growth factor (NGF) or neurotrophin-3, antioxidants, and Atoh1 induction have recently been applied, and some of them were considered for clinical application.
|
31348022 |
2019 |
|
hemangiopericytoma
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
The 2016 central nervous system (CNS) World Health Organisation (WHO) Update has merged the entities of meningeal solitary fibrous tumor (SFT) and hemangiopericytoma (HPC) into a single entity based on the presence of the nerve growth factor 1A (NGFI-A) binding protein 2 (NAB2)- signal transducer and activator of transcription 6 (STAT6) gene fusion in these tumors.
|
30233017 |
2019 |
|
Hepatitis
|
0.010 |
Biomarker
|
group |
BEFREE |
Nerve growth factor (NGF) has an anti-tumor effects through perivascular innervation of neovessels in HT1080 fibrosarcoma and HepG2 hepatitis tumor in nude mice.
|
31178329 |
2019 |
|
Hepatitis A
|
0.010 |
Biomarker
|
disease |
BEFREE |
Nerve growth factor (NGF) has an anti-tumor effects through perivascular innervation of neovessels in HT1080 fibrosarcoma and HepG2 hepatitis tumor in nude mice.
|
31178329 |
2019 |
|
Fibroid Tumor
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Are selective markers for the neuronal differentiation such as microtubule-associated protein 2 (MAP-2) and synaptophysin (SYP) as well as the nerve growth factor (NGF) expressed by fibroids, myometrium and eutopic endometrium?
|
31732726 |
2019 |
|
Macular Holes
|
0.010 |
Biomarker
|
disease |
BEFREE |
Internal limiting membrane insertion technique combined with nerve growth factor injection for large macular hole.
|
31823798 |
2019 |
|
prostatitis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Upregulation of TRPV1 in spinal dorsal root ganglion by activating NGF-TrkA pathway contributes to pelvic organ cross-sensitisation in rats with experimental autoimmune prostatitis.
|
31074030 |
2019 |
|
Retinopathy of Prematurity
|
0.010 |
Biomarker
|
disease |
BEFREE |
Topical application of NGF enhanced while intraocular injections of anti-NGF neutralizing antibody reduced pathological retinal vascularization in mice subjected to the ROP model.
|
30680928 |
2019 |
|
Sciatica
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
To discuss the current knowledge on the impact of commonly used biologic agents (i.e., anti-tumor necrosis factor-alpha [anti-TNF-α] and anti-nerve growth factor [anti-NGF]) in the management of low back pain with or without sciatica.
|
30576566 |
2019 |
|
West Syndrome
|
0.010 |
Biomarker
|
disease |
BEFREE |
We examined cerebrospinal fluid (CSF) concentrations for neurotrophins, nerve growth factor (β-NGF) and insulin-like growth factor (IGF-1) in children with infantile spasms between 1997 and 2010.
|
30503720 |
2019 |