Coronary Artery Disease
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
The synthesis of available evidence supports the fact that eNOS G894T andT-786C are associated with CAD.
|
20861627 |
2010 |
Coronary Artery Disease
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
The aim of this study was to investigate the role of endothelial nitric oxide synthase (eNOS) gene intron 4 a/b variable number of tandem repeats (VNTR) polymorphism and other risk factors in the development of CAD in subjects living in Southern Turkey.
|
15748612 |
2005 |
Coronary Artery Disease
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
The T allele of the missense Glu(298)Asp endothelial nitric oxide synthase gene polymorphism is associated with coronary heart disease in younger individuals with high atherosclerotic risk profile.
|
11755935 |
2002 |
Coronary Artery Disease
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
These findings suggest that the G894T polymorphism of the eNOS gene was not associated with CAD in Chilean individuals.
|
16616056 |
2006 |
Coronary Artery Disease
|
0.500 |
GeneticVariation
|
disease |
LHGDN |
In contrast to previous reports, homozygosity for the Asp298 variant of the 894G>T polymorphism in the eNOS gene was not found to be associated with risk of AMI, extent of CAD and in-hospital mortality after AMI.
|
18495009 |
2008 |
Coronary Artery Disease
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
This FSS-induced rise in SOD-2 expression in CC-genotype ECs effectively stabilizes their antiatherosclerotic phenotype and may explain not only the comparatively slow onset of CAD in homozygous carriers of the C-allele of the nos-3 gene but also define a general strategy for preventing endothelial dysfunction at the outset of atherosclerosis.
|
19696404 |
2009 |
Coronary Artery Disease
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Interestingly, a promoter variant of the NOS3 gene, the -786C variant, is insensitive to shear stress, and individuals homozygous for this single-nucleotide polymorphism (SNP) have an increased risk of developing coronary artery disease.
|
17009241 |
2006 |
Coronary Artery Disease
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Glu298Asp polymorphism of the endothelial nitric oxide synthase (eNOS) gene (NOS3) has been characterized as a risk factor of hypertension and coronary artery disease.
|
21816783 |
2011 |
Coronary Artery Disease
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
The endothelial nitric oxide synthase (eNOS) (4a/b) gene polymorphism contributes to coronary heart disease and hypertension risk.
|
12923396 |
2003 |
Coronary Artery Disease
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
The aim of this research was to discover whether the T-786C polymorphism in the promoter 5'-flanking region of the gene for endothelial nitric oxide synthase (eNOS) is associated with CAD.
|
20215811 |
2010 |
Coronary Artery Disease
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Association of endothelial nitric oxide synthase promoter region (T-786C) gene polymorphism with acute coronary syndrome and coronary heart disease.
|
18298848 |
2008 |
Coronary Artery Disease
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Recently, an endothelial nitric oxide synthase (ecNOS) gene polymorphism, the 27-bp repeat in intron 4 (ecNOS4), was reported to be related to the pathogenesis of coronary heart disease and terminal renal failure.
|
9535806 |
1998 |
Coronary Artery Disease
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
The purpose of this study was to determine the relationship between erectile dysfunction (ED), coronary artery disease (CAD), and T(-786)C and intron 4 a/b endothelial nitric oxide synthase (eNOS) polymorphisms in 419 patients with suspected or known CAD referred for coronary angiography.
|
19466514 |
2009 |
Coronary Artery Disease
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Common variants of the endothelial nitric oxide synthase gene and the risk of coronary heart disease among U.S. diabetic men.
|
16804086 |
2006 |
Coronary Artery Disease
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Endothelial nitric oxide synthase (eNOS) intron 4a/b polymorphism is associated with coronary artery disease and hypertension in various populations.
|
19574729 |
2009 |
Coronary Artery Disease
|
0.500 |
GeneticVariation
|
disease |
LHGDN |
We performed logistic regression analysis for the effect of eNOS intron 4 polymorphism and other coronary risk factors on multi-vessel CAD and endothelial function.
|
15825964 |
2005 |
Coronary Artery Disease
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Genetic etiology of coronary artery disease considering NOS 3 gene variant rs1799983.
|
25057159 |
2015 |
Coronary Artery Disease
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Intron 4 polymorphism of the endothelial nitric oxide synthase gene is associated with elevated blood pressure in type 2 diabetic patients with coronary heart disease.
|
11043380 |
2000 |
Coronary Artery Disease
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Several studies have evaluated the association between the G894T polymorphism located in an exon of endothelial nitric oxide synthase (eNOS) and the risk of premature CAD.
|
29100441 |
2017 |
Coronary Artery Disease
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
In this issue of Clinical Science, Agema and co-workers report the results of a genetic association study of eNOS (endothelial nitric oxide synthase) gene polymorphisms (-786T --> C, intron 4b --> a and Glu298 --> Asp) in patients with angiographic CAD (coronary artery disease), and/or prior MI (myocardial infarction) and a group of healthy population-based controls.
|
15283697 |
2004 |
Coronary Artery Disease
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
A missense mutation of the nitric oxide synthase (eNOS) gene (Glu298Asp) in five patients with coronary artery disease--case reports.
|
10451235 |
1999 |
Coronary Artery Disease
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Our findings, for the first time, indicate that NOS3 T allele strongly interacts with CETP B1 allele to augment the risk of CAD and T2DM in the population of Western Iran.
|
23157875 |
2012 |
Coronary Artery Disease
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
These results showed a smoking-dependent effect of the T-786C eNOS polymorphism on CAD in both Caucasian- and African-Brazilians.
|
16842798 |
2007 |
Coronary Artery Disease
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
These findings point to a role for NOS3 polymorphisms in CAD in the Chinese Han population, and may be useful for future investigations on the pathogenesis of CAD.
|
27323132 |
2016 |
Coronary Artery Disease
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
A smoking-dependent risk of coronary artery disease associated with a polymorphism of the endothelial nitric oxide synthase gene.
|
8564837 |
1996 |