|
Hypertensive disease
|
0.700 |
GeneticVariation
|
group |
BEFREE |
Association analysis revealed significant association of the ATP2B1 rs2070759 polymorphism with hypertension (P=5.3×10(-5); allelic odds ratio: 1.17 [95% CI: 1.09 to 1.26]).
|
20921432 |
2010 |
|
Hypertensive disease
|
0.700 |
GeneticVariation
|
group |
GWASCAT |
Genome-wide association study of blood pressure and hypertension.
|
19430479 |
2009 |
|
Hypertensive disease
|
0.700 |
Biomarker
|
group |
CTD_human |
Genome-wide association study of blood pressure and hypertension.
|
19430479 |
2009 |
|
Hypertensive disease
|
0.700 |
GeneticVariation
|
group |
GWASDB |
Genome-wide association study of blood pressure and hypertension.
|
19430479 |
2009 |
|
Hypertensive disease
|
0.700 |
Biomarker
|
group |
RGD |
[Effects of ANP upon ion pump activity and gene expression in aortic smooth muscle cells from spontaneously hypertensive rats].
|
20137670 |
2009 |
|
Hypertensive disease
|
0.700 |
Biomarker
|
group |
BEFREE |
For detection of polymorphisms all 22 PMCA1 exons from 44 patients with essential hypertension (based on rigorous clinical data in addition to a positive family history) and from 40 normotensives without a family history of hypertension were PCR amplified and subsequently subjected to combined single-strand conformation polymorphism (SSCP) and heteroduplex (HTX) analysis.
|
10425217 |
1999 |
|
Coronary Artery Disease
|
0.430 |
Biomarker
|
disease |
BEFREE |
Genetic factors play an important role in the cervico-cerebral large-artery atherosclerotic stenosis (LAS), and ATP2B1 gene has been associated with the process of atherosclerosis disorders, such as coronary artery disease and arterial stiffness.
|
29902063 |
2019 |
|
Coronary Artery Disease
|
0.430 |
GeneticVariation
|
disease |
GWASCAT |
Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.
|
29212778 |
2018 |
|
Coronary Artery Disease
|
0.430 |
GeneticVariation
|
disease |
GWASCAT |
Association analyses based on false discovery rate implicate new loci for coronary artery disease.
|
28714975 |
2017 |
|
Coronary Artery Disease
|
0.430 |
Biomarker
|
disease |
BEFREE |
The functions of RNF39 and ATP2B1 raise the possibility that genes involved in cardio-dysfunction may contribute to nonobstructive CAD in Caucasian women and may provide insights into novel approaches for therapy and prevention.
|
26534935 |
2016 |
|
Coronary Artery Disease
|
0.430 |
GeneticVariation
|
disease |
GWASCAT |
A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease.
|
26343387 |
2015 |
|
Coronary Artery Disease
|
0.430 |
GeneticVariation
|
disease |
BEFREE |
The ATP2B1 rs12817819 A allele is associated with increased risk for RHTN in hypertensive participants with documented CAD or suspected ischemic heart disease.
|
25385345 |
2014 |
|
Coronary Artery Disease
|
0.430 |
Biomarker
|
disease |
CTD_human |
Genome-wide association study in Han Chinese identifies four new susceptibility loci for coronary artery disease.
|
22751097 |
2012 |
|
Coronary Arteriosclerosis
|
0.310 |
Biomarker
|
disease |
BEFREE |
Genetic factors play an important role in the cervico-cerebral large-artery atherosclerotic stenosis (LAS), and ATP2B1 gene has been associated with the process of atherosclerosis disorders, such as coronary artery disease and arterial stiffness.
|
29902063 |
2019 |
|
Coronary Arteriosclerosis
|
0.310 |
Biomarker
|
disease |
CTD_human |
Genome-wide association study in Han Chinese identifies four new susceptibility loci for coronary artery disease.
|
22751097 |
2012 |
|
Cataract
|
0.300 |
Biomarker
|
disease |
CTD_human |
Changes in plasma membrane Ca2+ -ATPase expression and ATP content in lenses of hereditary cataract UPL rats.
|
15003327 |
2004 |
|
Pseudoaphakia
|
0.300 |
Biomarker
|
disease |
CTD_human |
Changes in plasma membrane Ca2+ -ATPase expression and ATP content in lenses of hereditary cataract UPL rats.
|
15003327 |
2004 |
|
Lens Opacities
|
0.300 |
Biomarker
|
phenotype |
CTD_human |
Changes in plasma membrane Ca2+ -ATPase expression and ATP content in lenses of hereditary cataract UPL rats.
|
15003327 |
2004 |
|
Coronary heart disease
|
0.110 |
Biomarker
|
disease |
BEFREE |
Genetic factors play an important role in the cervico-cerebral large-artery atherosclerotic stenosis (LAS), and ATP2B1 gene has been associated with the process of atherosclerosis disorders, such as coronary artery disease and arterial stiffness.
|
29902063 |
2019 |
|
Malignant Neoplasms
|
0.110 |
Biomarker
|
group |
BEFREE |
Together, these results suggest that ERβ promotes ccRCC cell invasion by altering the ERβ/circATP2B1/miR-204-3p/FN1 axis and that therapeutic targeting of this newly identified pathway may better prevent ccRCC progression.<b>Significance:</b> These results identify an ERβ/circATP2B1/miR-204-3p/FN1 signaling axis in RCC, suggesting ERβ and circular RNA ATP2B1 as prognostic biomarkers for this disease.<i>Cancer Res; 78(10); 2550-63.©2018 AACR</i>.
|
29490945 |
2018 |
|
Malignant Neoplasms
|
0.110 |
GeneticVariation
|
group |
GWASCAT |
Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.
|
27790247 |
2016 |
|
Coronary heart disease
|
0.110 |
GeneticVariation
|
disease |
GWASCAT |
Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.
|
27790247 |
2016 |
|
Myocardial Infarction
|
0.110 |
GeneticVariation
|
disease |
GWASCAT |
A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease.
|
26343387 |
2015 |
|
Myocardial Infarction
|
0.110 |
Biomarker
|
disease |
BEFREE |
In PROMIS, 4 of the 23 suggestive CAC loci (chr9p21, COL4A1, ATP2B1, and ABCA4) had significant associations with MI, consistent with their direction of effect on CAC.
|
23727086 |
2013 |
|
Coronary heart disease
|
0.110 |
GeneticVariation
|
disease |
GWASDB |
Genome-wide association study in Han Chinese identifies four new susceptibility loci for coronary artery disease.
|
22751097 |
2012 |