MIR383, microRNA 383, 494332

N. diseases: 65; N. variants: 0
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0152013
Disease: Adenocarcinoma of lung (disorder)
Adenocarcinoma of lung (disorder)
0.010 AlteredExpression disease BEFREE In conclusion, the results of the present study demonstrated that miR-383-5p was downregulated in LAC tissues. 28927114 2017
CUI: C0278876
Disease: Adult Medulloblastoma
Adult Medulloblastoma
0.010 AlteredExpression disease BEFREE In this study, we demonstrated significant downregulation of miR-383 in 23/29 (79%) MB samples and 7/7 (100%) MB cells lines. 23227829 2013
CUI: C0750927
Disease: Apraxia, Developmental Verbal
Apraxia, Developmental Verbal
0.010 Biomarker disease BEFREE Hence, this study aims to explore the function of miR-383-3p targeting IL1R2 on inflammatory injury of coronary artery endothelial cells (CAECs) in CAS. 29693751 2018
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
0.030 Biomarker phenotype BEFREE MicroRNA-383 is a tumor suppressor in human lung cancer, which functions to inhibit tumorigenesis of lung cancer cells both in vitro and in vivo. 27862077 2016
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
0.030 Biomarker phenotype BEFREE Also, the susceptibility of miR-383 as a tumor marker and the relationship between its aberrant expression and clinicopathological features were determined. qRT-PCR data showed that miR-383 was dysregulated during gastric tumorigenesis. 28243881 2017
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
0.030 Biomarker phenotype BEFREE The present study aimed to investigate the role of miR-383-5p in gastric carcinogenesis. 31365693 2019
CUI: C0007097
Disease: Carcinoma
Carcinoma
0.010 Biomarker group BEFREE In clinical samples, miR-383 was also found to be markedly downregulated in NSCLC carcinomas than in non-carcinoma lung tissues, and in advanced-stage carcinomas than in early-stage carcinomas. 27551765 2016
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
0.020 Biomarker disease BEFREE Both microRNA-383 and EPAS1 could serve as potential therapeutic targets in the treatment of lung cancer. 27862077 2016
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
0.020 AlteredExpression disease BEFREE The expression of miR-383 was significantly decreased, and the level of Wnt1 was significantly increased (P < 0.05) in lung cancer tissues and cells. 30426539 2018
CUI: C4721610
Disease: Carcinoma, Ovarian Epithelial
Carcinoma, Ovarian Epithelial
0.020 AlteredExpression disease BEFREE In stably miR-383-downregulated EOC cell lines, cancer proliferation, cell cycle progression, invasion and in vivo explant development were significantly suppressed. 27567588 2016
CUI: C4721610
Disease: Carcinoma, Ovarian Epithelial
Carcinoma, Ovarian Epithelial
0.020 Biomarker disease BEFREE Therefore, miR-383-5p/TRIM27 axis may be the potential target for the treatment of ovarian cancer. 30399596 2019
CUI: C0007222
Disease: Cardiovascular Diseases
Cardiovascular Diseases
0.010 Biomarker group BEFREE These findings highly indicate that miR-383-3p may be beneficial in the prevention of CAS and other cardiovascular diseases. 29693751 2018
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.020 Biomarker disease BEFREE LINC01128 expedited cells cellular process in CC by binding with miR-383-5p to release SFN. 31779593 2019
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.020 AlteredExpression disease BEFREE This study demonstrates that miR-383 could down-regulate PARP2 to protect against CC by inhibiting PI3K-AKT-MTOR signaling pathway. 29236322 2018
CUI: C0302592
Disease: Cervix carcinoma
Cervix carcinoma
0.020 Biomarker disease BEFREE LINC01128 expedited cells cellular process in CC by binding with miR-383-5p to release SFN. 31779593 2019
CUI: C0302592
Disease: Cervix carcinoma
Cervix carcinoma
0.020 AlteredExpression disease BEFREE This study demonstrates that miR-383 could down-regulate PARP2 to protect against CC by inhibiting PI3K-AKT-MTOR signaling pathway. 29236322 2018
CUI: C0278510
Disease: Childhood Medulloblastoma
Childhood Medulloblastoma
0.010 AlteredExpression disease BEFREE In this study, we demonstrated significant downregulation of miR-383 in 23/29 (79%) MB samples and 7/7 (100%) MB cells lines. 23227829 2013
Childhood Testicular Germ Cell Tumor
0.010 AlteredExpression disease BEFREE Abnormal testicular miR-383 expression may potentiate the connections between male infertility and testicular germ cell tumor. 21368870 2010
CUI: C0206698
Disease: Cholangiocarcinoma
Cholangiocarcinoma
0.010 Biomarker disease BEFREE In conclusion, miR-383 serves as a tumor-suppressive miR to regulate cholangiocarcinoma cell proliferation, migration, and invasion via directly targeting IRF1. 30145803 2018
CUI: C0699790
Disease: Colon Carcinoma
Colon Carcinoma
0.020 Biomarker disease BEFREE Transfection with a miR-383 mimic suppressed proliferation and inhibited cell migration and invasion in HT-29 and LoVo colon cancer cell lines. 29399173 2018
CUI: C0699790
Disease: Colon Carcinoma
Colon Carcinoma
0.020 AlteredExpression disease BEFREE We observed that CREPT was up-regulated but the expression of miR-383 was down regulated in both colon cancer cell lines and colon tumor tissues. 29938829 2018
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.020 AlteredExpression disease BEFREE PAX6 was upregulated in CRC tissues and was negatively correlated with miR‑383 expression. 29512711 2018
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.020 Biomarker disease BEFREE MicroRNA-383 acts as a tumor suppressor in colorectal cancer by modulating CREPT/RPRD1B expression. 29938829 2018
Conventional (Clear Cell) Renal Cell Carcinoma
0.010 AlteredExpression disease BEFREE Semi-quantitative real-time PCR was used to analyze the expression of miR-224 and miR-383 in 32 samples of ccRCC tumors (T) and in 32 matched control (C) samples. 21912701 2011
CUI: C0011884
Disease: Diabetic Retinopathy
Diabetic Retinopathy
0.020 Biomarker disease BEFREE MiR-383 was inversely correlated with AK077216 in DR patients. 31391356 2019