SCLY, selenocysteine lyase, 51540

N. diseases: 161; N. variants: 2
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.100 GeneticVariation disease BEFREE From June 2012 to July 2014, participants completed the Impact of Event Scale (IES) and Depression (DEP) and Anxiety (ANX) subscales of the Symptom CheckList-90-R (SCL-90) every 6 weeks. 28606893 2017
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.100 GeneticVariation disease BEFREE <b>Objective</b>: This study examined the construct validity of two widely-used instruments for the assessment of PTSD symptoms (Harvard Trauma Questionnaire [HTQ]; 16 items) and symptoms of anxiety and depression (Hopkins Symptom Check list-25 [HSCL-25]; 25 items) among Dutch and refugee patients with different linguistic backgrounds. 29038686 2017
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.100 GeneticVariation disease BEFREE All abbreviated forms were strongly correlated with the SCL-90-R for general psychopathology (r = 0.93-0.99), depression (r = 0.89-0.95), anxiety (r = 0.97-0.98), psychosis (r = 0.95-0.99), and obsessive-compulsive symptoms (r = 0.97). 31665694 2019
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.100 GeneticVariation disease BEFREE The results from the current study supported the use of the SCL-10 and WHO-5 as potential PROMs to capture symptom burden and quality of life within groups of people with anxiety or depression undergoing psychotherapy treatment. 29546787 2018
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.100 GeneticVariation disease BEFREE In this longitudinal study, 27 lung transplant recipients were prospectively examined for psychological distress (Symptom Checklist short version-9; SCL-K-9), health-related quality of life (EuroQOL five dimensions questionnaire; EQ-5D), depression (HADS-Depression scale), and socio-demographic and medical outcomes at two weeks, three months, six months and three years following LTx. 30961347 2019
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.100 GeneticVariation disease BEFREE A wide neuropsychiatric battery was employed including the following: symptoms checklist 90-R (SCL-90-R), Toronto alexithymia scale (TAS-20), Hamilton anxiety rating scale (HAMA), Beck depression inventory (BDI II), dissociative experiences scale (DES), traumatic experience checklist (TEC), somatoform dissociation questionnaire (SDQ-20), and temperament and character inventory-revised (TCI-R). 29092782 2018
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.100 GeneticVariation disease BEFREE Affective symptoms were measured at baseline and at four follow-ups using SCL-90 anxiety and depression subscales. 20064128 2010
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.100 GeneticVariation disease BEFREE Moreover, compared with the short-term prisoners, mindfulness training was more effective on the long-term prisoners in mindfulness level (<i>p</i> < .05), SCL-90 (<i>p</i> < .001), anxiety (<i>p</i> < .05), depression (<i>p</i> < .05), aggression (<i>p</i> < .05), total mood disturbance (<i>p</i> < .0l), and perceived stress (<i>p</i> < .0l). 31043102 2019
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.100 GeneticVariation disease BEFREE All of the subjects completed a uniform clinical evaluation that included the Unified Huntington's Disease Rating Scale-99, molecular testing to determine HD mutation status, the SCL-90-R, and the Center for Epidemiological Studies Depression Scale. 17210818 2007
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.100 GeneticVariation disease BEFREE Forty-three subjects (77%) evidenced mild depression of which 13 (23%) reported moderate-severe symptoms by the Beck Depression Inventory--a finding confirmed with Hamilton Rating Scale for Depression and the SCL-90-D scale. 2934456 1985
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.100 GeneticVariation disease BEFREE Individuals were assessed cross-sectionally for depression (PHQ-9), anxiety (GAD-7), post-traumatic stress disorder symptoms (PDS), somatic syndrome (SCL-90-R), alcohol dependence (ICD-10), functional impairment (PDS life functioning section), and self-perceived general physical health (SF-36). 31463614 2020
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.100 GeneticVariation disease BEFREE Anxiety and depression were measured using the HSCL-25, and condom use and sexual partner concurrency were assessed through self-report. 29156358 2018
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.100 GeneticVariation disease BEFREE Symptoms of anxiety and depression were assessed by the Hopkins Symptom Checklist-25 (HSCL-25), somatization was assessed by the Somatization Subscale of the Symptom-Checklist-90 (SCL-90), and the number of witnessed and experienced trauma was assessed by the Posttraumatic Diagnostic Scale (PDS/HTQ). 31088419 2019
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.100 GeneticVariation disease BEFREE Mothers reported symptoms of anxiety and depression three times during pregnancy (at 13.3 ± 1.1, 20.2 ± 1.5, and 33.8 ± 1.5 weeks of pregnancy, respectively) using the anxiety subscale of the Symptom Checklist (SCL-90), the Spielberger State and Trait Anxiety Inventory (STAI), and the Edinburgh Postnatal Depression Scale (EPDS). 29902667 2018
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.100 GeneticVariation disease BEFREE Demographics, lung function, anxiety (anxiety subscale of the 90-item symptom checklist (SCL-90-A)), depression (Beck depression inventory for primary care (BDI-PC)), exercise tolerance (six-minute walking distance test (6MWD)), and health status (Nijmegen clinical screening instrument (NCSI)) were assessed before and after a 12-week PR programme. 31434343 2019
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.100 GeneticVariation disease BEFREE Individual's completed measures of perfectionism (Frost-MPS), Emotional Inhibition (EIS), Depression (BDI-II), Anxiety (STAI-Y), Global symptoms (SCL-90-R), and interpersonal problems (IIP-32). 29621675 2018
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.100 GeneticVariation disease BEFREE Significant negative or positive correlations were observed between GH-IGF-1 concentrations and impairments on several EDI-2 subscales (drive for thinness, body dissatisfaction, interoceptive awareness, sense of ineffectiveness, interpersonal distrust, maturity fear) and on SCL-90 subitems (depression, hostility, obsessivity compulsivity, anxiety), suggesting a possible hormonal modulatory effect on specific aspects of ED psychopathology. 29179911 2018
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.100 GeneticVariation disease BEFREE Anxiety and depression were measured using the HSCL-25 and condom use and sexual partner concurrency were assessed through self-report. 29168066 2018
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.100 GeneticVariation disease BEFREE Among adolescents, those on EFV had lower scores on depression (HADS (Cohen's D: 0.3; P = 0.02) and SCL-90 (Cohen's D: 0.1; P = 0.02). 29220120 2018
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.100 GeneticVariation disease BEFREE We found differences between the eutocic and instrumental delivery groups in the SCL-90-R subscales somatisation (t = 6.98; p = 0.01), anxiety (t = 3.42; p < 0.05), depression (t = 5.20; p < 0.02) and psychoticism (t = 5.28; p < 0.01), and in the general indices global severity index (t = 5.57; p < 0.05) and positive symptoms (t = 5.21; p < 0.01). 31254963 2019
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.100 GeneticVariation disease BEFREE The primary outcome measure was severity of PTSD-symptoms (Harvard Trauma Questionnaire (HTQ)) and secondary outcome measures were depression and anxiety symptoms (Hopkins Symptom Checklist-25 (HSCL-25), Hamilton Depression and Anxiety rating scales (HAM-D, HAM-A)), somatisation (somatisation items of SCL-90 (SI-SCL-90)), quality of life (WHO-5-Well-being Index (WHO-5)) and functioning (Sheehan Disability Scale (SDS), Global Assessment of Functioning (GAF-F, GAF-S)). 30791342 2019
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.100 GeneticVariation disease BEFREE The comparison of the patient and control groups based on SCL-90-R findings demonstrated that the patient group scores in somatization, anxiety (p = 0.000), depression (p = 0.003), anger (p = 0.02), interpersonal sensitivity (p = 0.006), phobia (p = 0.001), paranoid thoughts (p = 0.012), psychosis (p = 0.031) subscales and additional subscale (p = 0.014) and general symptom index (p = 0.001) scores were higher. 30472336 2019
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.100 Biomarker disease BEFREE The effect of childhood adversity was significantly moderated by genetic vulnerability for depression in the model of both follow-up psychotic experiences (SCL-90-R) and follow-up psychotic trait liability (CAPE). 21835094 2012
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.100 Biomarker disease BEFREE Compared to the control group, the intervention group demonstrated significantly greater improvement in the Arnetz and Hasson stress score (AHSS, p = 0.019), the total Symptoms Checklist 8 score (SCL-8D, p = 0.037), the SCL-8D anxiety sub-score (p = 0.017), and on a summarized feedback score (p = 0.026), but not on the depression subscale. 28028732 2017
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.100 Biomarker disease BEFREE Statistically higher SCL-90-R scores were found in active patients for obsessive-compulsive disorder (P = 0.026), depression (P = 0.013), anxiety (P = 0.013), phobic anxiety (P = 0.002), psychoticism (P = 0.007), global severity index (GSI) (P = 0.005) and positive symptom total (PST) (P = 0.001). 30689871 2019